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Protein Overview: FBpp0311691, FBp...

General Information:
Name(s) found: FBpp0311691 [FlyBase]
FBpp0305165 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • type=protein; loc=2R:join(12755817..12755896,12755996..12756584); ID=FBpp0311691; name=Ef1beta-PC; parent=FBgn0028737,FBtr0345627; dbxref=FlyBase:FBpp0311691,FlyBase_Annotation_IDs:CG6341-PC; MD5=db65b931eba2f027cda91e367d763098; length=222; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:join(12755817..12755896,12755996..12756584); ID=FBpp0305165; name=Ef1beta-PB; parent=FBgn0028737,FBtr0332947; dbxref=REFSEQ:NP_524808,GB_protein:AAF57941,FlyBase:FBpp0305165,FlyBase_Annotation_IDs:CG6341-PB; MD5=db65b931eba2f027cda91e367d763098; length=222; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 222 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    cytosol [ISS][NAS]
    eukaryotic translation elongation factor 1 complex [IEA][ISS][NAS]
    Biological Process: translational elongation [IEA][ISS][NAS]
    Molecular Function: translation elongation factor activity [IEA][ISS][NAS]
    translation release factor activity [ISS]
    guanyl-nucleotide exchange factor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFGDVTTPQ GLKELNAFLA DNSYISGYTP SKADLSVFDA LGKAPSADNV NVARWYRHIA  60
   61 SFEAAERAAW SGTPLPQLAG GKPTVAAAAK PAADDDDDVD LFGSDDEEDE EAERIKQERV 120
  121 AAYAAKKSKK PALIAKSSVL LDVKPWDDET DMKEMENNVR TIEMDGLLWG ASKLVPVGYG 180
  181 INKLQIMCVI EDDKVSIDLL QEKIEEFEDF VQSVDIAAFN KI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..91] PSI-BLAST 11.522879 Class delta GST
    2 View Details [92..222] PSI-BLAST 39.0 SOLUTION STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR DOMAIN FROM HUMAN ELONGATION FACTOR-ONE BETA, NMR, 20 STRUCTURES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  1.65945313523198 bayes_pls_golite062009
  • binding
    		•  1.45526122320486 bayes_pls_golite062009
  • transferase activity
    		•  1.05573069897577 bayes_pls_golite062009
  • catalytic activity
    		•  0.963623964325467 bayes_pls_golite062009
  • receptor binding
    		•  0.490857233487879 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.46030380837916 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  0.44372379417457 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.385619646192102 bayes_pls_golite062009
  • RNA binding
    		•  0.382017633056715 bayes_pls_golite062009
  • peptide binding
    		•  0.22963019108532 bayes_pls_golite062009
  • glutathione transferase activity
    		•  0.20688408808374 bayes_pls_golite062009
  • DNA binding
    		•  0.175092771820973 bayes_pls_golite062009
    2
    Term Confidence Notes
  • translation elongation factor activity
    		•  12.3173391557088 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  7.81664120156021 bayes_pls_golite062009
  • translation regulator activity
    		•  7.77673515271111 bayes_pls_golite062009
  • binding
    		•  2.83703195704118 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.61354904861592 bayes_pls_golite062009
  • actin binding
    		•  1.90340345597574 bayes_pls_golite062009
  • protein binding
    		•  1.74079757896683 bayes_pls_golite062009
  • signal transducer activity
    		•  1.65423237700268 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.65423237700268 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.63487486759233 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.669814437561164 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.651746786837234 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.555069882515023 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.260738180200771 bayes_pls_golite062009
  • actin monomer binding
    		•  0.2298282502586 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle