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Protein Overview: CG5522-PE, CG552...

General Information:
Name(s) found: CG5522-PB / FBpp0086181 [FlyBase]
CG5522-PE / FBpp0086180 [FlyBase]
CG5522-PA / FBpp0086177 [FlyBase]
Description(s) found:
Found 44 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5522 (CG5522, FBgn0034158). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12671196..12679981. It has the cytological map location 53D8-53D9. Based on sequence similarity, it is predicted to have molecular function</span>: guanyl-nucleotide exchange factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: small GTPase mediated signal transduction. 5 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG5522 (CG5522, FBgn0034158). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12671196..12679981. It has the cytological map location 53D8-53D9. Based on sequence similarity, it is predicted to have molecular function</span>: guanyl-nucleotide exchange factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: small GTPase mediated signal transduction. 5 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG5522 (CG5522, FBgn0034158). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12671196..12679981. It has the cytological map location 53D8-53D9. Based on sequence similarity, it is predicted to have molecular function</span>: guanyl-nucleotide exchange factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: small GTPase mediated signal transduction. 5 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 702 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: small GTPase mediated signal transduction [IEA]
    Molecular Function: guanyl-nucleotide exchange factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRYSEISRD LSTDNLRYSE LSRKPTTDYN GYTGQAYAAT QFKQSSPPPP PSQQQQQPTR  60
   61 VSKQRSPNTN GSAHTMACLR QEKTYKEQQM EPPSMQPQAS KTLNIKSTRR KNSIGCLNSF 120
  121 SSSPDSPGCY YTIAASAAPP SKSQSLPAHA SIKQLDAVIL SALRVPADVL ANQITLLDFP 180
  181 VFAQIQPDEL SSCAWTKKDK HVNTPNIVAF TKRFNHTSFW TVQEILNAEQ PKQRAEIITH 240
  241 FIKVAKKLHE LNNLHSLFAI ISAMQSASIY RLTKTWACLS KKDRNAFDRL SDIFSDQDNW 300
  301 ANLRSYLESL RLPCIPYLGL FLTDLIYIDL AHPHKGGLEP EQRRNKMNNI LRVISNYQQS 360
  361 NYKHLQKHEA TQKYLTSIRY IEELQNIFEE DQYKRSLNLE PASPSGPSSS SCSSKESFNV 420
  421 EVVTPALGCL NLSPAKTIGS MRMASGTKFV PGHRKCRSLG TKFRSSSLPR NFAEKCQCCI 480
  481 VMIAPGIGTI SNKRCRCRRI FGKIATHNHS DGHPHHLHLE LDPSQVQPRH HLLDDSVLEH 540
  541 SDALSQADLT SLESAEGIMC DFTGSDCDLM SPEAAAAMHG CVRRKTVQKE GRKPAVASWQ 600
  601 RYWLQIWANS LVYFPPKSFK GSERNDFKRE PCKVCPLDGW YAHVSDNTKH KNTFELCHRT 660
  661 LGTVYRFRTD SPQMTHLWSN AICKLATMRV PKPLPTNLMS FE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..429] PSI-BLAST 67.0 Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
    2 View Details [430..563] deduced N/A No confident structure predictions are available.
    3 View Details [564..702] PSI-BLAST 23.69897 No description for 2dtcA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.597587183571285 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.32323692785606 bayes_pls_golite062009
  • protein binding
    		•  0.29116370406325 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle