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View Structure Prediction Details

Protein: CG5522-PE, CG552...
Organism: Drosophila melanogaster
Length: 702 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5522-PE, CG552....

Description E-value Query
Range
Subject
Range
gi|125809909|ref... - GA18948-PA [Drosophila pseudoobscura], GA18948 [Drosophila pseudoobscura pseudoobscura]
gi|54636452, gi|... - gi|54636452|gb|EAL25855.1| GA18948 [Drosophila pseudoobscura pseudoobscura], gi|125809909|ref|XP_001...
412.0 [0..1] [702..1]

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Predicted Domain #1
Region A:
Residues: [1-429]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRYSEISRD LSTDNLRYSE LSRKPTTDYN GYTGQAYAAT QFKQSSPPPP PSQQQQQPTR  60
   61 VSKQRSPNTN GSAHTMACLR QEKTYKEQQM EPPSMQPQAS KTLNIKSTRR KNSIGCLNSF 120
  121 SSSPDSPGCY YTIAASAAPP SKSQSLPAHA SIKQLDAVIL SALRVPADVL ANQITLLDFP 180
  181 VFAQIQPDEL SSCAWTKKDK HVNTPNIVAF TKRFNHTSFW TVQEILNAEQ PKQRAEIITH 240
  241 FIKVAKKLHE LNNLHSLFAI ISAMQSASIY RLTKTWACLS KKDRNAFDRL SDIFSDQDNW 300
  301 ANLRSYLESL RLPCIPYLGL FLTDLIYIDL AHPHKGGLEP EQRRNKMNNI LRVISNYQQS 360
  361 NYKHLQKHEA TQKYLTSIRY IEELQNIFEE DQYKRSLNLE PASPSGPSSS SCSSKESFNV 420
  421 EVVTPALGC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.0
Match: 1xd4A
Description: Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.597587183571285 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.32323692785606 bayes_pls_golite062009
protein binding 0.29116370406325 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [430-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNLSPAKTIG SMRMASGTKF VPGHRKCRSL GTKFRSSSLP RNFAEKCQCC IVMIAPGIGT  60
   61 ISNKRCRCRR IFGKIATHNH SDGHPHHLHL ELDPSQVQPR HHLLDDSVLE HSDALSQADL 120
  121 TSLESAEGIM CDFT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [564-702]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSDCDLMSPE AAAAMHGCVR RKTVQKEGRK PAVASWQRYW LQIWANSLVY FPPKSFKGSE  60
   61 RNDFKREPCK VCPLDGWYAH VSDNTKHKNT FELCHRTLGT VYRFRTDSPQ MTHLWSNAIC 120
  121 KLATMRVPKP LPTNLMSFE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.69897
Match: 2dtcA
Description: No description for 2dtcA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle