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Protein Overview: CG8399-PA

General Information:
Name(s) found: CG8399-PA / FBpp0086349 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8399 (CG8399, FBgn0034067). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11905244..11912139. It has the cytological map location 52D14. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: dopamine beta-monooxygenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: histidine catabolic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 647 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: histidine catabolic process [IEA]
    Molecular Function: dopamine beta-monooxygenase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMQALTMRSW LATLVTALLA VAIWPDPGQS LPQGAPETVC DTMLPFHSGG SVLPQNSVSP  60
   61 FSVETSSSTL GQGQTLRVDL TGVPAGLSFG GYMIQARNRN PPHQIIGQFG PARDGTIKLM 120
  121 NCENSVNNSA THSNAGPKQQ VILEWQSPVD FLGQVVFNAT IAQSYNEFWV GVPSQPVQIV 180
  181 RRDLSAAPPL PTQSPSAPAG TTRAPYVPPS YVAPNNVVAV SSDPIYNGCG QSKNCFGFPD 240
  241 GCVATKSCTS ITVVTVRGDV FEFEIQSGKG TNAAYVAVGL SDDAKMGDDL TTECVPENGR 300
  301 VNLYSSLTSA SPYSAVRSNV NQNSARLLDA SIVDGVIYCR VQRDAVTNVQ GRTFDLRNGK 360
  361 YHLLVASGSS LKENSVGYHD IGRLPSAQPI NLAEVQDLSG SSRLLIQLHG AFMIAAWIGT 420
  421 TSLGIIFARY FKQTWVGSQS CGTDQWFAWH RLLMVTTWSL TVAAYVLIWV ELKQAVWHAH 480
  481 SIIGLITVIL CFIQPIGALF RPGPNDKKRP YFNWGHWLGG NLAHILGIVT IFFSVKLPKA 540
  541 ELPEWMDWIL VSFVVVHVLV HLIFSIGGMA SERHLSQRAN TFQMGDMSHH QQHAMRNGMS 600
  601 MERKMDAPYA GMRKGLLGVY GVVLILFVTV LILLVVLAPI EQFLGKS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] FFAS03 1.05 CD1, alpha-3 domain; CD1, alpha-1 and alpha-2 domains
    2 View Details [204..380] PSI-BLAST 13.09691 Cytochrome domain of cellobiose dehydrogenase
    3 View Details [381..647] PSI-BLAST 39.30103 Mitochondrial cytochrome b subunit, C-terminal domain; Mitochondrial cytochrome b subunit, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.804544680433615 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • catalytic activity
    		•  0.292921973619001 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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