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Protein Overview: Strn-Mlck-PG

General Information:
Name(s) found: Strn-Mlck-PG / FBpp0086414 [FlyBase]
Description(s) found:
Found 13 descriptions.
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  • The gene Stretchin-Mlck is referred to in FlyBase by the symbol Dmel\Strn-Mlck (CG18255, FBgn0013988). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11834431..11873458. It has the cytological map location 52D4-52D9. There is experimental evidence that it has the molecular function</span>: myosin light chain kinase activity; calmodulin-dependent protein kinase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protein amino acid phosphorylation. 12 alleles are reported. No phenotypic data is available. It has 13 annotated transcripts and 13 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 785 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein amino acid phosphorylation [IEA][ISS][NAS]
    Molecular Function: ATP binding [IEA]
    calmodulin-dependent protein kinase activity [IDA]
    structural constituent of cytoskeleton [ISS]
    protein serine/threonine kinase activity [NAS]
    myosin light chain kinase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDYGVEAAA ASVAVEGPPE PPSGQPSVSL GPDRVAVAWC GPPYDGGCMI TGFIIEMQTI  60
   61 GDENCDEDSW QQVTRVVDSL AYTVKNLQPE RQYRFRVRAE NIHGRSAPGQ ASELVQITNT 120
  121 PQRSTSSDAS DRFGQATVSV QSGGDFKSRF EIIEELGKGR FGIVYKVQER GQPEQLLAAK 180
  181 VIKCIKSQDR QKVLEEISIM RALQHPKLLQ LAASFESPRE IVMVMEYITG GELFERVVAD 240
  241 DFTLTEMDCI LFLRQVCDGV AYMHGQSVVH LDLKPENIMC HTRTSHQIKI IDFGLAQRLD 300
  301 TKAPVRVLFG TPEFIPPEII SYEPIGFQSD MWSVGVICYV LLSGLSPFMG DTDVETFSNI 360
  361 TRADYDYDDE AFDCVSQEAK DFISQLLVHR KEDRLTAQQC LASKWLSQRP DDSLSNNKIC 420
  421 TDKLKKFIIR RKWQKTGNAI RALGRMANLS VSRRNSAIAM GVLSSPRPSI SGLGMLTTSA 480
  481 IGSGTSSQMT SLHEEEDDFS GEMPPVEKRT VLKLRDKSQC SERSDSGYSE CSNCSGAQET 540
  541 LLLSLAKSKL EAIAKASTLP TVVHDTEQPV SLELPTKGEA IMRSDFTNTI KMRKKSLEDS 600
  601 AAREKPRSKP QVKPLLCESK LKVSQLKDRF QVSPAPASAS ASASAANKPP LAYGPFKIAK 660
  661 VASVGRISRT EEPGRSGRGA PSVSGKGKSP QVRSMPSSPL PQRSATPTRL MSQRVREAAE 720
  721 RLAQQHTVAS AQRHLGNGRG TGTGNGNGNS NSNGNGNGNT AETNRESRAR RLINRFNSET 780
  781 QHITS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..132] PSI-BLAST 16.69897 No description for 2nziA was found.
    2 View Details [133..414] PSI-BLAST 62.30103 No description for 1yrpA was found.
    3 View Details [415..501] PSI-BLAST 64.045757 Twitchin, kinase domain
    4 View Details [502..684] deduced N/A No confident structure predictions are available.
    5 View Details [685..785] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle