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Protein Overview: FBpp0300975, CG8...

General Information:
Name(s) found: FBpp0300975 [FlyBase]
FBpp0300974 [FlyBase]
CG8249-PA / FBpp0086445 [FlyBase]
Description(s) found:
Found 32 descriptions.
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  • type=protein; loc=2R:complement(11731723..11732516,11732809..11733117,11733189..11733651); ID=FBpp0300975; name=CG8249-PC; parent=FBgn0034045,FBtr0308818; dbxref=FlyBase:FBpp0300975,FlyBase_Annotation_IDs:CG8249-PC,REFSEQ:NP_001246350,GB_protein:AFH08104; MD5=7ef9bd763d96f0108b051e46a3796a86; length=521; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:complement(11731723..11732516,11732809..11733117,11733189..11733651); ID=FBpp0300974; name=CG8249-PB; parent=FBgn0034045,FBtr0308817; dbxref=FlyBase:FBpp0300974,FlyBase_Annotation_IDs:CG8249-PB,REFSEQ:NP_001246349,GB_protein:AFH08103; MD5=7ef9bd763d96f0108b051e46a3796a86; length=521; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8249 (CG8249, FBgn0034045). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11731595..11734865. It has the cytological map location 52C8. Based on sequence similarity, it is predicted to have molecular function</span>: glucose transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 521 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    Molecular Function: glucose transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEQHQNLNQ NGSESNGKQA RIVSGLDRLL KTPPPGEQTR AVRRQVIAVI LANVGVFSTG  60
   61 MTLAMPTATL HQLKDTTEPV HLNDSQASWF ASVNALSAPI GGLLSGFLLD RIGRKKSLIV 120
  121 LNVLIILAWI LLATPSESDQ NAFFWQLIVS RFMLGVGMGL ASAPPGVYAA EISVPKTRGS 180
  181 LILGTSISVA GGITILYGIG YCIRDDFRLI ALICCGYQLV ALLCVLPLPE SHCWLLSKKR 240
  241 VTEAKRSLNY FRGFNKSDEI THPQVLEEFQ LLQKSLQQRN TAVKESFWRN LHEPEVYKPL 300
  301 VILMSLFAFQ QLTGIFVVIV FAVQISQEAG IEIDPFMCAV LIGLARLITT CPMGYILEWW 360
  361 GRRRAGIIST LGMSVCMFLL AGHSQIEILK EVPYLPVVAI VGFIVLSTLG LYTLPFFMIS 420
  421 ELFPQKVRGP ASGLTVAVGM FISFVVLKTY PGIKEYLGMS NCFIIFGVMA LFALIFVYLA 480
  481 LPETRRRTLL EIEEQFRSGR SKSQNQADVE MKEVFVRKPE E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..521] PSI-BLAST 29.39794 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.29248638217469 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.29248638217469 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.6904339767429 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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