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Protein Overview: fus-PE, fus-PD, ...

General Information:
Name(s) found: fus-PE / FBpp0086479 [FlyBase]
fus-PD / FBpp0086477 [FlyBase]
fus-PF / FBpp0086476 [FlyBase]
Description(s) found:
Found 49 descriptions.
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  • The gene fusilli is referred to in FlyBase by the symbol Dmel\fus (CG8205, FBgn0023441). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11544823..11564198. It has the cytological map location 52B3-52B5. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: epidermal growth factor receptor signaling pathway. 34 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
  • The gene fusilli is referred to in FlyBase by the symbol Dmel\fus (CG8205, FBgn0023441). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11544823..11564198. It has the cytological map location 52B3-52B5. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: epidermal growth factor receptor signaling pathway. 34 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
  • The gene fusilli is referred to in FlyBase by the symbol Dmel\fus (CG8205, FBgn0023441). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11544823..11564198. It has the cytological map location 52B3-52B5. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: epidermal growth factor receptor signaling pathway. 34 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 967 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: epidermal growth factor receptor signaling pathway [IGI]
    Molecular Function: nucleic acid binding [IEA]
    mRNA binding [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVPEHVVSL YIATCGQNGS GLGSDEKEII LLVFVLLEVS TGQIVGTKQI LVRPDGYFIK  60
   61 DRTISSSSDN SSVTNNTASS PPLAIGDANN GSGSTSGNGN SLENGSELIL PIAEAQAAGK 120
  121 PLSEAIEEFD AYLRSLSLHD TEIKLVTDGQ LPLRQCLHRE ASAKDVELPA YYNRFSDLRK 180
  181 EFLRYKSGDL ARALVPVKDV KKMLQAPTLP MPQSIAEMLG ELNISSVEDN DFYIRESRDM 240
  241 VTVIQTLLQA GHKFAANELV NLVLEPGICS IDDEVDGNCI VRARGLPWQS SDQDIAKFFR 300
  301 GLNVAKGGVA LCLSPLGRRN GEALIRFVCQ EHRDMALKRH KHHIGTRYIE VYRASGEDFL 360
  361 AIAGGASNEA QAFLSKGAQV IIRMRGLPYD ATAKQVLDFF TTGDTPPCHV LDGNEGVLFV 420
  421 KKPDGRATGD AFVLFANETD APKALGRHRE SIGQRYIELF RSTTAEVQQV LNRSMDPKNY 480
  481 ESGGGHSQPP LIAQLPTMQL PLLPQVGAHS LSHSLGASPA NLCPPVPPPA LPLPTQHLIT 540
  541 SGTTKNCIRL RGLPYEAMVE HILHFLDDFA KHIIYQGVHM VINAQGQPSG EAFIQMDLEE 600
  601 SARLCAQRRH NHYMMFGKKY RYIEVFQCSG DDMNMVLNGG LASPVAQPPP PHLGHAHKQQ 660
  661 SLLAATTGMF SSAGQSPTTV AAGTAQSPLG GTHTHTHPHS HAHAHATGHA HAAAAAAHHG 720
  721 LSASSAMLPG LSAAASASGL ASFMSAGQQS AAAAAHSAAS LQNAAVALAP QGYALNPFSL 780
  781 PPPGSAAAAA ASTPALLAQQ QAQFIAQQSL LVRQQAAAAA LAAEQQQQQQ QQQQLYASAM 840
  841 LQQHPLYLQQ QQQQQQLYAS AMLQQGQPQF VLMQRPSAAY LPPFPLSYMS AAGAASGVGV 900
  901 APGAAVAGAA AAASPSASNS SLSQSMKRSY ENAFQQEAAG AAAAASAAKR ALTRQPSSVY 960
  961 SYYNSGI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..188] PSI-BLAST 8.522879 Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP
    2 View Details [189..256] PSI-BLAST 28.69897 No description for 2dhsA was found.
    3 View Details [257..508] PSI-BLAST 55.154902 Nuclear ribonucleoprotein A1 (RNP A1, UP1)
    4 View Details [509..727] FFAS03 3.88 Nuclear ribonucleoprotein A1 (RNP A1, UP1)
    5 View Details [728..865] PSI-BLAST 7.0 Sec24
    6 View Details [866..967] PSI-BLAST 15.30103 poly(A) binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.722279828632226 bayes_pls_golite062009
  • hydrolase activity
    		•  0.29272620969648 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.24934115119652 bayes_pls_golite062009
  • nuclease activity
    		•  0.239989310123501 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.950788308762215 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.29562225149076 bayes_pls_golite062009
    4
    Term Confidence Notes
  • binding
    		•  0.787118623292657 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.0269483316710413 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.26

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle