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Protein Overview: Asx-PA

General Information:
Name(s) found: Asx-PA / FBpp0086622 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Additional sex combs is referred to in FlyBase by the symbol Dmel\Asx (CG8787, FBgn0000142). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10391514..10399951. It has the cytological map location 51A5-51A6. It is reported to have molecular function</span>: transcription activator activity; transcription repressor activity; chromatin binding. There is experimental evidence that it is involved in the biological process</span>: syncytial blastoderm mitotic cell cycle. 39 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; organ system; embryonic tagma; adult; embryonic abdomen; thoracic segment; anatomical structure; embryonic head; embryonic thorax; embryonic segment; cuticle. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1669 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    chromatin [IDA]
    Biological Process: syncytial blastoderm mitotic cell cycle [IMP]
    sex comb development [TAS]
    chromatin silencing [NAS]
    Molecular Function: transcription activator activity [NAS]
    chromatin binding [NAS]
    transcription repressor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTITPDTTT TTSSQHQQLL IPQADQHHQP MLQQQSLLAA PPPTMIMEHV NLVDDDEKDP  60
   61 LALEQLEVSP STKHTHSLRR HLPRIIVKPI PPEKKPMAPS EEAAVSTAPA PPTRLICSRR 120
  121 IQQQQQVKAA AAAAAAAAAA AAAAAAAAQA QATSSYPSAI SPGSKAGTSQ ASTMREVLAS 180
  181 IPGFSVKPRR RSNKKLTTAA QIEQTKDGKI DLETPDSILA STNLRALLNK QTFSLLPPLY 240
  241 QYNLIQLLPS VDREASELEQ PSSSASGGSP SEAIRLSASC LNNEFFARAC LEWRERLSEG 300
  301 EFTPENQLKL KTEAEREKNK LDPWKLKHFE PFWGEKNSRG KDKDKLESDC KNQKLSASIK 360
  361 SEPKPPATSQ QKPLQQATCD NETELKFDLS TKCETTSAKT TVAVAVADKS STFPPTGSQN 420
  421 NVLNEQQRRV LKRPSSSPSQ RKQAPTTIAT INLDDDLDEL PSTSKDSKQP KMDEIVPNAS 480
  481 GNVVAAPMVD VVDHSAVEMK IKDEQQHQRQ HQPLINSTCD KIEPSECSKE MIVAMKQVDS 540
  541 KEDVDSIASA AAMPAIAAVT PHTPKPEALA PNPDVANQFV SYLQNVELAA ETKAPLDNSN 600
  601 EADITTGTNS HDFVFSDTID HAYFQEHQST INHNFFTSSS SSNTATTAAN KLEEHSDKPE 660
  661 DSPLPIASSI SGSTPASSIT STSCTSSSSS SASMSSSCSS SNSGSTTTAP TTSSSAGAPT 720
  721 APLTLAAAAE TTLANVQAML STVAKLQQQQ QELPVELNSN EMYQHVQHDW NFGDIKLSSS 780
  781 QSSGDQQRNL SHEAIDLMDV VQDADVIDDI MHNDVCHDVL GDEDEGDQEE DEDDEVVECM 840
  841 TEEQQLIDED SEAVREIVDK LQQHQQQQNQ QQHHQQLHIQ DVVQLAQHSF MPQAHSEFGN 900
  901 DIGQEMLCDA VPMSAAEMEV SSTVITNSSN SNDSSNNISL CSSTNSLTIN QMPHQASQQP 960
  961 QQNAQSNAQQ QRQILVDSNG QIIGNFLLQQ QRQQQQQQLL QQFTLQAAAA QQQQQQQQQH1020
 1021 QQQQQQQQQA TSSNSLGKTL PVALRNGTQQ FLSPNLIAQQ HQQQQQQQLE QHQQQATAQQ1080
 1081 KHQQIQQFAL QQAQLHQRQL LAQAANNNLL QQQQQQQQNV ALPTTQAKFI AKPLNIISMT1140
 1141 RPANASPTTA ATTANTASIP SAYANVVAVT GAQQQQSPPV PAPQQQTVQQ QQLANHNSNM1200
 1201 QQLPNVLTMK TLPPSGVPTT IAQQRLQPKM PTGKGRKATS NRLPPGAVNL ERSYQICQAV1260
 1261 IQNSPNRENL KAQLRPPAAI LNQHQPTTTT APAPINPVTL NVSTVAATPM SNITTATGSM1320
 1321 AAAVAAAPPQ NVLKQEELLV SGAVGAGALP AGLPPNVMGV GRPGVYKVIG PRMSGFPRKK1380
 1381 YVQRKPSPTT LIRHVFSPGP GGATATAQQL QMLQQHHQST TSPVPVQNPQ QPAPEQLIHQ1440
 1441 NGNGQYVLVH RANVGAADNQ APRASSAPPM HQNQFVTVQN PLHSINGIPM GGRGRPASVD1500
 1501 TTAGSGNVIA PPISATDALH HHHHEMQQQQ QHQQPQPLGN VGAAANIVRR NIAAGPNIAY1560
 1561 IDGSNTNSSA VALMEAGNNY IVTTNASPTA APSPINQQPQ SQPTGTQHQH PLLQLHQTGE1620
 1621 NTPPGNEATA TANNCACSLN AMVICQQCGA FCHDDCIGAA KLCVACVIR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..168] MSA 1.097993 View MSA. No confident structure predictions are available.
    2 View Details [169..271] MSA 3.109986 View MSA. No confident structure predictions are available.
    3 View Details [272..725] FFAS03 1.05 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
    4 View Details [726..807] deduced N/A No confident structure predictions are available.
    5 View Details [808..885] deduced N/A No confident structure predictions are available.
    6 View Details [886..990] deduced N/A No confident structure predictions are available.
    7 View Details [991..1243] deduced N/A No confident structure predictions are available.
    8 View Details [1244..1394] deduced N/A No confident structure predictions are available.
    9 View Details [1395..1534] deduced N/A No confident structure predictions are available.
    10 View Details [1535..1669] FFAS03 1.02 No description for 2e6sA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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