Protein Overview: RN-tre-PB

General Information:
Name(s) found:	RN-tre-PB / FBpp0086730 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7303241\|gb\|AAF58303.1\| tre oncogene-related protein, isoform B [Drosophila melanogaster] [NCBI NR] gi\|2286196\|gb\|AAC48286.1\| tre oncogene-related protein [Drosophila melanogaster] [NCBI NR] gi\|17737469\|ref\|NP_523736.1\| tre oncogene-related protein, isoform B [Drosophila melanogaster] [NCBI NR] The gene tre oncogene-related protein is referred to in FlyBase by the symbol Dmel\RN-tre (CG8085, FBgn0020620). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9872320..9878191. It has the cytological map location 50C23. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: Rab GTPase activator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of Rab GTPase activity. 6 alleles are reported. The phenotypes of these alleles are annotated with: mushroom body; Kenyon cell. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] >CG8085-PB translation from_gene[CG8085 RN-tre FBgn0020620] seq_release:3 mol_weight=53731 cds_boundaries:(2R:9,053,001..9,054,550[-]) aa_length:457 transcript_info:[CG8085-RB seq_release:3] gene_info:[gene symbol:RN-tre synonyms:[CG13351] FBgn0020620 [hmr_yeast5_DM3-1_pombe.fasta] (AE003816) RN-tre gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta] CG8085-PB, isoform B [Drosophila melanogaster]gi\|17737469\|ref\|NP_523736.1\| CG8085-PB [Drosophila melanogaster]gi\|2286196\|gb\|AAC48286.1\| tre oncogene-related protein [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2R:complement(9875789..9875942,9876003..9876388,9876448..9877129,9877190..9877341); ID=FBpp0086730; name=RN-tre-PB; parent=FBgn0020620,FBtr0087604; dbxref=GB_protein:AAF58303.1,FlyBase:FBpp0086730,FlyBase_Annotation_IDs:CG8085-PB,REFSEQ: [fly-100309-contam.fasta] CG8085-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] tre oncogene-related protein CG8085-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] tre oncogene-related protein [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:complement(9875789..9875942,9876003..9876388,9876448..9877129,9877190..9877341); ID=FBpp0086730; name=RN-tre-PB; parent=FBgn0020620,FBtr0087604; dbxref=GB_protein:AAF58303.1,FlyBase:FBpp0086730,FlyBase_Annotation_IDs:CG8085-PB,REFSEQ:NP_523736,GB_protein:AAF58303; MD5=76f6f704818876eff71e94939a2c52f2; length=457; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:complement(9875789..9875942,9876003..9876388,9876448..9877129,9877190..9877341); ID=FBpp0086730; name=RN-tre-PB; parent=FBgn0020620,FBtr0087604; dbxref=GB_protein:AAF58303.1,FlyBase:FBpp0086730,FlyBase_Annotation_IDs:CG8085-PB,REFSEQ:NP_523736,GB_protein:AAF58303; MD5=76f6f704818876eff71e94939a2c52f2; length=457; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Tre oncogene-related protein OS=Drosophila melanogaster GN=RN-tre PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2R:complement(9875789..9875942,9876003..9876388,9876448..9877129,9877190..9877341); ID=FBpp0086730; name=RN-tre-PB; parent=FBgn0020620,FBtr0087604; dbxref=GB_protein:AAF58303.1,FlyBase:FBpp0086730,FlyBase_Annotation_IDs:CG8085-PB,REFSEQ:NP_523736,GB_protein:AAF58303,FlyMine:FBpp0086730,modMine:FBpp0086730; MD5=76f6f704818876eff71e94939a2c52f2; length=457; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2R:complement(join(13989685..13989836,13988943..13989624,13988498..13988883,13988284..13988437)); ID=FBpp0086730; name=RN-tre-PB; parent=FBgn0020620,FBtr0087604; dbxref=GB_protein:AAF58303.1,FlyBase:FBpp0086730,FlyBase_Annotation_IDs:CG8085-PB,REFSEQ:NP_523736,GB_protein:AAF58303,FlyMine:FBpp0086730,modMine:FBpp0086730; MD5=76f6f704818876eff71e94939a2c52f2; length=457; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:complement(join(13989685..13989836,13988943..13989624,13988498..13988883,13988284..13988437)); ID=FBpp0086730; name=RN-tre-PB; parent=FBgn0020620,FBtr0087604; dbxref=GB_protein:AAF58303.1,FlyBase:FBpp0086730,FlyBase_Annotation_IDs:CG8085-PB,REFSEQ:NP_523736,GB_protein:AAF58303,FlyMine:FBpp0086730,modMine:FBpp0086730; MD5=76f6f704818876eff71e94939a2c52f2; length=457; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of A1Z9K4, Related to the N terminus of tre oncogene, isoform B OS=Drosophila melanogaster GN=RN-tre PE=1 SV=1 [DROME.fasta.20160308] FBpp0086730 type=protein; loc=2R:complement(join(13989685..13989836,13988943..13989624,13988498..13988883,13988284..13988437)); ID=FBpp0086730; name=RN-tre-PB; parent=FBgn0020620,FBtr0087604; dbxref=GB_protein:AAF58303.1,FlyBase:FBpp0086730,FlyBase_Annotation_IDs:CG8085-PB,REFSEQ:NP_523736,GB_protein:AAF58303,FlyMine:FBpp0086730,modMine:FBpp0086730; MD5=76f6f704818876eff71e94939a2c52f2; length=457; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:complement(join(13989685..13989836,13988943..13989624,13988498..13988883,13988284..13988437)); ID=FBpp0086730; name=RN-tre-PB; parent=FBgn0020620,FBtr0087604; dbxref=GB_protein:AAF58303.1,FlyBase:FBpp0086730,FlyBase_Annotation_IDs:CG8085-PB,REFSEQ:NP_523736,GB_protein:AAF58303,UniProt/TrEMBL:Q7KQC4,FlyMine:FBpp0086730,modMine:FBpp0086730; MD5=76f6f704818876eff71e94939a2c52f2; length=457; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	457 amino acids
Gene Ontology:
Cellular Component:	intracellular [IEA]
Biological Process:	regulation of Rab GTPase activity [IEA]
Molecular Function:	Rab GTPase activator activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDGEQQEAL VKRAEDERED IFRRYELGLD PSNVVDSWEN PTFEIYHRTD KYGFLHDSRL  60
   61 PSTRDAQEVH RNKIEMERDK KWMKMLNQWP PPQDKLHKRV YKGIPDRVRM VAWNKLLDIQ 120
  121 QSINNNAGVY LRMLQLARKY STETRQIDAD VNRQFRDNLA FRERYSVKQC SLFNVLNAYS 180
  181 IYNSELGYCQ GMACVAGVLL LYLHEEEAFW ALNTLITDQK YGMHGLFIEG FPKLTRFIDH 240
  241 HDRIMSKIMR KLHKHFTKHN VDALLYAIKW FFVVFVERVP FSLSLRVWDI FMLDGDRVIL 300
  301 SMAITILYLH KDELLRLKDM DAIIEYLQVR LHKNFGYSDD DAIQALERVM KKLKDLKLDV 360
  361 PPPAKSNEFP TRKLGDFVEA DMEKKIGRRR NDYTDAEKQV ITDVISRQEQ NAIDVQSTVS 420
  421 YETSECATGE SCVTHKSLHC LSTNPNACFK QSTYPTC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..70]	deduced	N/A	No confident structure predictions are available.
2	View Details	[71..361]	PSI-BLAST	46.522879	No description for 2qq8A was found.
3	View Details	[362..457]	deduced	N/A	No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.87

Protein Overview: RN-tre-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: