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Protein Overview: mip120-PA

General Information:
Name(s) found: mip120-PA / FBpp0086789 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Myb-interacting protein 120 is referred to in FlyBase by the symbol Dmel\mip120 (CG6061, FBgn0033846). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9393947..9400617. It has the cytological map location 50A14. There is experimental evidence that it has the molecular function</span>: protein binding; DNA binding. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; sperm motility; oogenesis; negative regulation of transcription from RNA polymerase II promoter. 12 alleles are reported. The phenotypes of these alleles are annotated with: eye; egg chamber; spermatozoon. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 950 amino acids

    Gene Ontology:
    Cellular Component: polytene chromosome [IDA]
    Myb complex [IDA]
    chromatin [IDA]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IMP]
    eggshell chorion gene amplification [IC]
    sperm motility [IMP]
    oogenesis [IMP]
    determination of adult lifespan [IMP]
    Molecular Function: DNA binding [IDA]
    protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTSGGNLDS LDDTEPLPEL SFEDFLEPTS EKSSQHMEIE ALDSEEDNIG GEDLADPAND  60
   61 SLNTPQFKKN VVHILEDKRL NSSGLTVLKS HAIKMVTAGG TPPAKAQVTD VKILNKLKPI 120
  121 PSSTLKIGST TIATKSTPGS ITKTLGNLTQ IRTKDGQVIF VQKSVPGTQS STAVTGSPSG 180
  181 GIRRLVAPSG IQKAVLSKGV TMASTGLVKA AVPAKASTSV PGSAITLKGI QPLAGGTAKA 240
  241 STSSTTATTS PSLAQPNKIQ VVRTADGKII KINQAGPSLL VNAKQGTGTT VTPGGSAATS 300
  301 VKLSPSTGNV VLNKPVGQVV VRTETPVKTA TGSVASASAT PGKMLVQSGG KQILVSNKNI 360
  361 IKLSPNASAT SSTTHTTGGQ TPSTSSGLHA IQLPGKGGIQ YVRVLNNNKS AAGTSATASI 420
  421 PKTVQTQKIT VVRPPAATGV PATSTTTSAA AASPAAASKA NLAMGNTNKI VMRSMGGSIV 480
  481 PLPSVQTLVS KRALGAISNA SKPASAASSS ATPSASQELP RKHRLTDLNV QLKQSASVSS 540
  541 EASDSSDAGP EAKKPRYVIT MQQGSQKAAS QPVQKLINRT ANVQRVVSSS TSPSSNSTKK 600
  601 IYNYVQPTGS NGAKYMICNS GVPQSSTSAM RRGYTGYVEN KTRRPPPISP QQHRFKQMGP 660
  661 QQQSKHQQLQ AQAKQRIRQQ QLPTEQSTPI KVEPKLPTLP PGVKANVPAK PLFEVLKPPA 720
  721 TAAAAGAVDP LGGMTSRRKH CNCSKSQCLK LYCDCFANGE FCQDCTCKDC FNNLDYEVER 780
  781 ERAIRSCLDR NPSAFKPKIT APNSGDMRLH NKGCNCKRSG CLKNYCECYE AKIPCSSICK 840
  841 CVGCRNMEDR PDVDMDSLDG LMGVEGQKKD KAKNKQLNEN RANIYFTDDV IEATIMCMIS 900
  901 RIVMHEKQNV AVEDMEREVM EEMGESLTQI IAFAKEKQET SQIDESKPSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..146] MSA 2.164996 View MSA. No confident structure predictions are available.
    2 View Details [147..363] MSA 1.177995 View MSA. No confident structure predictions are available.
    3 View Details [364..568] MSA 1.169983 View MSA. No confident structure predictions are available.
    4 View Details [569..698] MSA 2.15798 View MSA. No confident structure predictions are available.
    5 View Details [699..950] FFAS03 1.27 16-heme cytochrome c HmcA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  1.46714744827479 bayes_pls_golite062009
  • catalytic activity
    		•  0.223774911842048 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle