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Protein Overview: mos-PA

General Information:
Name(s) found: mos-PA / FBpp0086978 [FlyBase]
Description(s) found:
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  • gi|7303406|gb|AAF58463.1| mos [Drosophila melanogaster] [NCBI NR]
  • gi|24653187|ref|NP_610817.1| mos [Drosophila melanogaster] [NCBI NR]
  • gi|108743717|gb|ABG02167.1| IP11267p [Drosophila melanogaster] [NCBI NR]
  • The gene mos is referred to in FlyBase by the symbol Dmel\mos (CG8767, FBgn0033773). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8638988..8640441. It has the cytological map location 49C2. There is experimental evidence that it has the molecular function</span>: protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of TOR signaling pathway; protein amino acid phosphorylation. 2 alleles are reported. The phenotype of these alleles is annotated with: ovary. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG8767-PA translation from_gene[CG8767 CG8767 FBgn0033773] seq_release:3 mol_weight=40991 cds_boundaries:(2R:7,816,410..7,817,615[-]) aa_length:364 transcript_info:[CG8767-RA seq_release:3] gene_info:[gene symbol:CG8767 FBgn0033773 gene_boundaries:(2R [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V6G3) CG8767 protein [DrosMelano7227.FASTAC.txt]
  • (AE003821) CG8767 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8767-PA [Drosophila melanogaster]gi|24653187|ref|NP_610817.1| CG8767-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(8639199..8639952,8640012..8640225,8640281..8640407); ID=FBpp0086978; name=mos-PA; parent=FBgn0033773,FBtr0087865; dbxref=FlyBase:FBpp0086978,FlyBase_Annotation_IDs:CG8767-PA,GB_protein:AAF58463.1,REFSEQ:NP_610817,GB_protein [fly-100309-contam.fasta]
  • CG8767-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • IP11267p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • mos CG8767-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(8639199..8639952,8640012..8640225,8640281..8640407); ID=FBpp0086978; name=mos-PA; parent=FBgn0033773,FBtr0087865; dbxref=FlyBase:FBpp0086978,FlyBase_Annotation_IDs:CG8767-PA,GB_protein:AAF58463.1,REFSEQ:NP_610817,GB_protein:AAF58463; MD5=55e66151a73495960f1b76fc3560590c; length=364; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(8639199..8639952,8640012..8640225,8640281..8640407); ID=FBpp0086978; name=mos-PA; parent=FBgn0033773,FBtr0087865; dbxref=FlyBase:FBpp0086978,FlyBase_Annotation_IDs:CG8767-PA,GB_protein:AAF58463.1,REFSEQ:NP_610817,GB_protein:AAF58463; MD5=55e66151a73495960f1b76fc3560590c; length=364; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • IP11267p OS=Drosophila melanogaster GN=mos PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(8639199..8639952,8640012..8640225,8640281..8640407); ID=FBpp0086978; name=mos-PA; parent=FBgn0033773,FBtr0087865; dbxref=FlyBase:FBpp0086978,FlyBase_Annotation_IDs:CG8767-PA,GB_protein:AAF58463.1,REFSEQ:NP_610817,GB_protein:AAF58463,FlyMine:FBpp0086978,modMine:FBpp0086978; MD5=55e66151a73495960f1b76fc3560590c; length=364; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(12752776..12752902,12752507..12752720,12751694..12752447)); ID=FBpp0086978; name=mos-PA; parent=FBgn0033773,FBtr0087865; dbxref=FlyBase:FBpp0086978,FlyBase_Annotation_IDs:CG8767-PA,GB_protein:AAF58463.1,REFSEQ:NP_610817,GB_protein:AAF58463,FlyMine:FBpp0086978,modMine:FBpp0086978; MD5=55e66151a73495960f1b76fc3560590c; length=364; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(12752776..12752902,12752507..12752720,12751694..12752447)); ID=FBpp0086978; name=Mos-PA; parent=FBgn0033773,FBtr0087865; dbxref=FlyBase:FBpp0086978,FlyBase_Annotation_IDs:CG8767-PA,GB_protein:AAF58463.1,REFSEQ:NP_610817,GB_protein:AAF58463,FlyMine:FBpp0086978,modMine:FBpp0086978; MD5=55e66151a73495960f1b76fc3560590c; length=364; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • IP11267p OS=Drosophila melanogaster GN=Mos PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0086978 type=protein; loc=2R:complement(join(12752776..12752902,12752507..12752720,12751694..12752447)); ID=FBpp0086978; name=Mos-PA; parent=FBgn0033773,FBtr0087865; dbxref=FlyBase:FBpp0086978,FlyBase_Annotation_IDs:CG8767-PA,GB_protein:AAF58463.1,REFSEQ:NP_610817,GB_protein:AAF58463,FlyMine:FBpp0086978,modMine:FBpp0086978; MD5=55e66151a73495960f1b76fc3560590c; length=364; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(12752776..12752902,12752507..12752720,12751694..12752447)); ID=FBpp0086978; name=Mos-PA; parent=FBgn0033773,FBtr0087865; dbxref=FlyBase:FBpp0086978,FlyBase_Annotation_IDs:CG8767-PA,GB_protein:AAF58463.1,REFSEQ:NP_610817,GB_protein:AAF58463,UniProt/TrEMBL:Q1EC11,FlyMine:FBpp0086978,modMine:FBpp0086978; MD5=55e66151a73495960f1b76fc3560590c; length=364; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 364 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein amino acid phosphorylation [IGI]
    positive regulation of TOR signaling pathway [IGI]
    Molecular Function: ATP binding [IEA]
    protein kinase activity [IGI]
    protein serine/threonine kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDLLLNTPK RKQLLKDGPP VPTRCQVLGR GAYGTVFKAI YRDRSVAVKI IRAQAASTLH  60
   61 NESHLLNLEH RNIVRLLKLE SAADFGLVIM ECPRGQSLQR IVDTLALPLM HRVLITLDVV 120
  121 AALRYCHSQN VLHLDVKPTN ILVALGTKSS ITCNSSKIKV KRSYICKLCD FGSSIEMGEF 180
  181 CAWQEPSVAK GTLRYMSPEA LRSDTLTEAS DIYSLGITMW QLQARRLPYH TLDCNETIAY 240
  241 QVVKHELRPD NYHQLKILAL DSPIDCDWDL AHESTANVIC RRANTSARRN LSLDPSYTVG 300
  301 RDLKKKRHRN RLALHFDSPA PEGSACSESA YSQLYKSCWV SAPELRLSSI QLKHELEFIL 360
  361 CHST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..364] PSI-BLAST 54.522879 CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein kinase activity
    		•  4.80423821582894 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  4.62563910354252 bayes_pls_golite062009
  • kinase activity
    		•  4.49248003612191 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.22000749960953 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  3.79514095722095 bayes_pls_golite062009
  • transferase activity
    		•  3.46855149744418 bayes_pls_golite062009
  • catalytic activity
    		•  1.58699080719302 bayes_pls_golite062009
  • ATP binding
    		•  1.52245797843186 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.49413620362406 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.4569583921893 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.24912655063747 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.24864625022733 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.21461303193661 bayes_pls_golite062009
  • nucleotide binding
    		•  1.2042473055528 bayes_pls_golite062009
  • binding
    		•  0.816171432010054 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  0.72813241420523 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  0.65582668281291 bayes_pls_golite062009
  • protein binding
    		•  0.644217880248374 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.58533773607974 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle