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Protein Overview: E(Pc)-PA, E(Pc)-PB

General Information:
Name(s) found: E(Pc)-PB / FBpp0087239 [FlyBase]
E(Pc)-PA / FBpp0087238 [FlyBase]
Description(s) found:
Found 34 descriptions.
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  • The gene Enhancer of Polycomb is referred to in FlyBase by the symbol Dmel\E(Pc) (CG7776, FBgn0000581). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7339722..7351535. It has the cytological map location 47F13-47F14. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: chromatin organization. 14 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Enhancer of Polycomb is referred to in FlyBase by the symbol Dmel\E(Pc) (CG7776, FBgn0000581). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7339722..7351535. It has the cytological map location 47F13-47F14. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: chromatin organization. 14 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2023 amino acids

    Gene Ontology:
    Cellular Component: [NOT]polytene chromosome chromocenter [IDA]
    polytene chromosome [IDA]
    intercalary heterochromatin [NAS]
    chromatin [NAS]
    Biological Process: chromatin organization [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKLSFRARH LDPSKQMPIY LAEELPDLPE YSAINRAVPQ MPSGMEKEEE SEHHLQRAIC  60
   61 TGLIIPTPEV LQTDQPFYDA YYPPDYKMPR QMIHMQPLGL DTEVPDYDMD SADEDWLSQQ 120
  121 QRLELTELKF EQMMDRLEKS SGQTVVTLNE AKSLLNQDDE TSISVYDYWL NKRLKMQHPL 180
  181 ILTVKTESRP GASSNNPYLA FRRRTEKMQT RKNRKNDEAS YEKMLKLRRD LQRATTILEM 240
  241 VRRREETKRD HLKMTVNIFE KRVEMRDFNG AVYSELNSQY KNTRPAYNPL YTNQYSQGAA 300
  301 AVGTAGAILA ALPTGLLPGG AGAAGNANVF GSASQYLNSS NLTMDAISGS GNGNSSRKEK 360
  361 RPYKKRKHKL PRDKQQHQQQ QTQQHQQQQY LPASGGAGVS PAHHLPHHLH HLSRQQSASP 420
  421 AANDSIADSE EEDYFGAGAQ NGNKLGSESE EETPFAFRRR SSCVYLPTRQ RDGRYPWDSA 480
  481 DEDMAPSGAC SDAKYRYTLT SLNYPRPRCI GFARRRLGRG GRILLDRATT NFDDFWSQLD 540
  541 YTVMESVTVN KCRDKIKQRD PDQLCKPSSP PTVVDLVPAG KPVDGEHPVP ELIKEEPSSD 600
  601 TEKPVAATES GRESKERELE EKFENDVDDE FVASDDENVS RLGIYSSAVT LPQSCADLRQ 660
  661 KRRRLRRKKQ QLRELNAAKR LKRSSEAVAT AEDVQLEDED TKPDLRPLPR AYLQRLALIL 720
  721 GQKLKVEEDD NTEVSENVAP ELLEMNDPEQ LQPPRANHQQ HHRSNHNNNN NTVLNNNNSS 780
  781 SSNVMNKDVS ISEKINVIKQ EAEELVGGKC EDQPVASTSA AAAAARAAEA AAAAEAASST 840
  841 TTLAAPNPGP SLEEVAKTIK REMIDADDSN EPLSSIRTAA VMLSTQTSVS ELMDDEAEDD 900
  901 VNLAQLSSII RHTAVKKELE AQQHQQQVQH EQMQAARKME EDEAAPCLNQ LPDVIRLRNI 960
  961 RNSQVHARPK DLFVQAPVDE EFNADYMGGL SPTSSQRLDI CNELLSEIRR DWLHFRPKTP1020
 1021 TDELSDSQDC EVGKTCDSHA VDWTQDTPIS VELNRLGKRE AEESDSSSYF LSSGFKYRDL1080
 1081 ESDAQLLQTV QAQDYARGSS KSPNCSGSGS GSALEFNLSG GDSLNDINNL LGCDDEDDNH1140
 1141 EHMLDNILQE CAMDDPKALN QATNFWNGIL DGEAAVDEVE MADQLLDCID EKKSKVGAAD1200
 1201 TSKRAGRNRK ARLIQAPVGS SAFTVCPTAE TLKERELFFS QAPPVEVPPK EKTPAEVELP1260
 1261 EVVVKETANL PVKVEAVEKP QSEVLPVAPQ PQQLQPQAIT LPTTQLINIP AQISTQKQHQ1320
 1321 QPQVTQLLNQ FANAGPQIIA RTEYGGGAAV GDIVTITPHT GSSPLPTLTA QQQLQHQLAQ1380
 1381 AQLRNVTVQQ RQATPQNPNQ NQNPQQQLLF QMQRDPSRSL TPLQAAGAGA TGNHLIYTTS1440
 1441 CGEIVTAGAA ASASQKVTYA IQKAGVSSGG ATTASIGPNT VITLSNVKVQ NDDISSGGSG1500
 1501 NSGSSVNIIN TASGQQLAVH SIAGMQQQGQ QQVQQVTTST PLLVATPTRN NVQQQQQQLV1560
 1561 QQQPIVWRQV SGTNTAVATT AVLSTTVDSS PKAVTNQILW TSRATQKRQL NGPENTDINK1620
 1621 LLLNRKLPRK QQIQQQHQQI QLTKQQLQQL VQHEELDDLV ATSTGNSGDQ METGDGLQQQ1680
 1681 QQQQQQQQQL QKLSKVIKMS QFPLLVSDVS LQQQQSVSGQ AQQQQLKPNS AAAIAANHNY1740
 1741 SLHPASTAII TAQATPQQAN KIFLTSSNSG GGGSAGNFTI ATASELQAAA AGQKLHYKEL1800
 1801 PNSNLKLNFV SSAGTGEQTQ QVGATTVLLN KSQQQQQQQQ HQKLKTLATT GNSQTGQGDK1860
 1861 RVLYTSLLNV KPLQKNNSGQ MQMQLGPGGL QQVLRGRLNN SAIITRTLPL GTTVNSTGGA1920
 1921 VGPTTTTIRQ LVTTNANNVS SQDGNLLSAK EVGKALTVEQ VIASANNGGV VLPTSNNNNN1980
 1981 NNGSGAGGNG GPLNSGVNAT GAGGGGSTGA GVGGAGVTST INR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..196] MSA 1.043971 View MSA. No confident structure predictions are available.
    2 View Details [197..283] deduced N/A No confident structure predictions are available.
    3 View Details [284..388] PSI-BLAST 14.522879 No description for 2d9eA was found.
    4 View Details [389..607] deduced N/A No confident structure predictions are available.
    5 View Details [608..703] deduced N/A No confident structure predictions are available.
    6 View Details [704..847] deduced N/A No confident structure predictions are available.
    7 View Details [848..1045] deduced N/A No confident structure predictions are available.
    8 View Details [1046..1194] deduced N/A No confident structure predictions are available.
    9 View Details [1195..1392] PSI-BLAST 6.0 Sec24
    10 View Details [1393..1440] deduced N/A No confident structure predictions are available.
    11 View Details [1441..1668] MSA 1.237996 View MSA. No confident structure predictions are available.
    12 View Details [1669..1811] deduced N/A No confident structure predictions are available.
    13 View Details [1812..2023] MSA 1.176996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle