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Protein Overview: dare-PA

General Information:
Name(s) found: dare-PA / FBpp0087272 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene defective in the avoidance of repellents is referred to in FlyBase by the symbol Dmel\dare (CG12390, FBgn0015582). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7178490..7180676. It has the cytological map location 47F1. Based on sequence similarity, it is predicted to have molecular function</span>: electron carrier activity; NADPH-adrenodoxin reductase activity. There is experimental evidence that it is involved in the biological process</span>: olfactory behavior; steroid biosynthetic process; metamorphosis; molting cycle, chitin-based cuticle; pupariation. 12 alleles are reported. The phenotypes of these alleles are annotated with: thoracico-abdominal ganglion; fan shaped body; optic lobe; embryonic/larval anterior spiracle; antennal lobe; egg chamber; ellipsoid body; mouth hooks. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 466 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISS][NAS]
    mitochondrion [IDA][NAS]
    Biological Process: pupariation [IMP]
    cholesterol catabolic process [ISS]
    molting cycle, chitin-based cuticle [IMP][NAS]
    courtship behavior [NAS]
    phototaxis [NAS]
    steroid biosynthetic process [IDA][IEP][NAS]
    metamorphosis [IMP]
    olfactory behavior [IMP][NAS]
    pheromone metabolic process [NAS]
    Molecular Function: electron carrier activity [ISS][NAS]
    binding [IEA]
    ferredoxin-NADP+ reductase activity [NAS]
    NADPH-adrenodoxin reductase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGINCLNIFR RGLHTSSARL QVIQSTTPTK RICIVGAGPA GFYAAQLILK QLDNCVVDVV  60
   61 EKLPVPFGLV RFGVAPDHPE VKNVINTFTK TAEHPRLRYF GNISLGTDVS LRELRDRYHA 120
  121 VLLTYGADQD RQLELENEQL DNVISARKFV AWYNGLPGAE NLAPDLSGRD VTIVGQGNVA 180
  181 VDVARMLLSP LDALKTTDTT EYALEALSCS QVERVHLVGR RGPLQAAFTI KELREMLKLP 240
  241 NVDTRWRTED FSGIDMQLDK LQRPRKRLTE LMLKSLKEQG RISGSKQFLP IFLRAPKAIA 300
  301 PGEMEFSVTE LQQEAAVPTS STERLPSHLI LRSIGYKSSC VDTGINFDTR RGRVHNINGR 360
  361 ILKDDATGEV DPGLYVAGWL GTGPTGVIVT TMNGAFAVAK TICDDINTNA LDTSSVKPGY 420
  421 DADGKRVVTW DGWQRINDFE SAAGKAKGKP REKIVSIEEM LRVAGV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..466] PSI-BLAST 67.0 Adrenodoxin reductase of mitochondrial p450 systems

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NADPH-adrenodoxin reductase activity
    		•  5.80270482091908 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  4.45434904225178 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.10828870968712 bayes_pls_golite062009
  • antioxidant activity
    		•  1.49429830917872 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  1.39990343076756 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  1.29733355244701 bayes_pls_golite062009
  • catalytic activity
    		•  1.13824203225664 bayes_pls_golite062009
  • thioredoxin-disulfide reductase activity
    		•  0.844975371289313 bayes_pls_golite062009
  • binding
    		•  0.794954996246594 bayes_pls_golite062009
  • dihydrolipoyl dehydrogenase activity
    		•  0.68737141906442 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors
    		•  0.379282693663222 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  0.31095562417378 bayes_pls_golite062009
  • oxygen-dependent protoporphyrinogen oxidase activity
    		•  0.0706880697754912 bayes_pls_golite062009
  • protein binding
    		•  0.0171008177759692 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle