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Protein Overview: skf-PB

General Information:
Name(s) found: skf-PB / FBpp0113061 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • The gene skiff is referred to in FlyBase by the symbol Dmel\skf (CG30021, FBgn0050021). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7113962..7120056. It has the cytological map location 47E1. Based on sequence similarity, it is predicted to have molecular function</span>: guanylate kinase activity. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 556 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [ISS]
    Biological Process: NONE FOUND
    Molecular Function: protein binding [IEA]
    guanylate kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEAVMASDI NWDPALSKLI STLKESENLS NDQEIDFLKA LLESKELNAL VNVHTKVAKV  60
   61 GRDDRLAPVL STSAQVLYEV LEQLSQHCHL NDDCKEAFHL LQDSHLQHLL FAHDAIAQKD 120
  121 FYPHLPEAPV EMDEDEETIK IVQLVKSNEP LTGAQSTEPI VGATIKTDEE SGKIIIARIM 180
  181 HGGAADRSGL IHVGDEVIEV NNINVEGKTP GDVLTILQNS EGTITFKLVP ADNKGAQRES 240
  241 KVRVRAHFDY NPDVDPYIPC KEAGLAFQRG DVLHIVAQDD AYWWQARKEH ERSARAGLIP 300
  301 SRALQERRIL HDRTQKNGTD LDSKQNDDFD REQIATYEEV AKLYPRPGVF RPIVLIGAPG 360
  361 VGRNELRRRL IARDPEKFRS PVPYTTRPMR TGEVAGREYI FVAREKMDAD IEAGKFVEHG 420
  421 EYKGHLYGTS AESVKSIVNA GCVCVLSPHY QAIKTLRTAQ LKPFLIHVKP PELDILKATR 480
  481 TEARAKSTFD EANARSFTDE EFEDMIKSAE RIDFLYGHFF DVELVNGELV NAFEQLVQNV 540
  541 QRLENEPVWA PSMWVQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..64] PSI-BLAST 3.30103 2.1 Angstrom crystal structure of the PALS-1-L27N and PATJ L27 heterodimer complex
    2 View Details [65..236] PSI-BLAST 24.39794 solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
    3 View Details [237..556] PSI-BLAST 45.09691 Psd-95; Guanylate kinase-like domain of Psd-95

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.18270433521719 bayes_pls_golite062009
  • binding
    		•  2.4093171025758 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  1.9239399157391 bayes_pls_golite062009
  • PDZ domain binding
    		•  1.88298566187849 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.84086757311516 bayes_pls_golite062009
  • guanylate kinase activity
    		•  1.80396483614769 bayes_pls_golite062009
  • protein binding
    		•  1.15557714383339 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.683298345987 bayes_pls_golite062009
  • catalytic activity
    		•  0.304516551414824 bayes_pls_golite062009
  • structural molecule activity
    		•  0.248599616863115 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle