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Protein Overview: CG11883-PB

General Information:
Name(s) found: CG11883-PB / FBpp0087375 [FlyBase]
Description(s) found:
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  • gi|7303719|gb|AAF58768.1| CG11883, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|19921980|ref|NP_610598.1| CG11883, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|17862642|gb|AAL39798.1| LD42374p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG11883 (CG11883, FBgn0033538). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6505161..6532804. It has the cytological map location 47B1. Based on sequence similarity, it is predicted to have molecular function</span>: 5'-nucleotidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: nucleotide catabolic process. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • >CG11883-PB translation from_gene[CG11883 CG11883 FBgn0033538] seq_release:3 mol_weight=78521 cds_boundaries:(2R:5,702,725..5,705,312[+]) aa_length:713 transcript_info:[CG11883-RB seq_release:3] gene_info:[gene symbol:CG11883 FBgn0033538 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003829) CG11883 gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG11883-PB, isoform B [Drosophila melanogaster]gi|17862642|gb|AAL39798.1| LD42374p [Drosophila melanogaster]gi|19921980|ref|NP_610598.1| CG11883-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(6525503..6526067,6526131..6526217,6526271..6526834,6526973..6527487,6527551..6527790,6527859..6527954,6528019..6528093); ID=FBpp0087375; name=CG11883-PB; parent=FBgn0033538,FBtr0088283; dbxref=GB_protein:AAF58768.1,FlyBase:FBpp00 [fly-100309-contam.fasta]
  • CG11883-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD42374p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(6525503..6526067,6526131..6526217,6526271..6526834,6526973..6527487,6527551..6527790,6527859..6527954,6528019..6528093); ID=FBpp0087375; name=CG11883-PB; parent=FBgn0033538,FBtr0088283; dbxref=GB_protein:AAF58768.1,FlyBase:FBpp0087375,FlyBase_Annotation_IDs:CG11883-PB,REFSEQ:NP_610598,GB_protein:AAF58768; MD5=2efe269c0210a5ae48f5e89e102cfb3a; length=713; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(6525503..6526067,6526131..6526217,6526271..6526834,6526973..6527487,6527551..6527790,6527859..6527954,6528019..6528093); ID=FBpp0087375; name=CG11883-PB; parent=FBgn0033538,FBtr0088283; dbxref=GB_protein:AAF58768.1,FlyBase:FBpp0087375,FlyBase_Annotation_IDs:CG11883-PB,REFSEQ:NP_610598,GB_protein:AAF58768; MD5=2efe269c0210a5ae48f5e89e102cfb3a; length=713; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG11883, isoform B OS=Drosophila melanogaster GN=CG11883 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(6525503..6526067,6526131..6526217,6526271..6526834,6526973..6527487,6527551..6527790,6527859..6527954,6528019..6528093); ID=FBpp0087375; name=CG11883-PB; parent=FBgn0033538,FBtr0088283; dbxref=GB_protein:AAF58768.1,FlyBase:FBpp0087375,FlyBase_Annotation_IDs:CG11883-PB,REFSEQ:NP_610598,GB_protein:AAF58768,FlyMine:FBpp0087375,modMine:FBpp0087375; MD5=2efe269c0210a5ae48f5e89e102cfb3a; length=713; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • CG11883, isoform B OS=Drosophila melanogaster GN=CG11883 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2R:join(10637998..10638562,10638626..10638712,10638766..10639329,10639468..10639982,10640046..10640285,10640354..10640449,10640514..10640588); ID=FBpp0087375; name=CG11883-PB; parent=FBgn0033538,FBtr0088283; dbxref=GB_protein:AAF58768.1,FlyBase:FBpp0087375,FlyBase_Annotation_IDs:CG11883-PB,REFSEQ:NP_610598,GB_protein:AAF58768,FlyMine:FBpp0087375,modMine:FBpp0087375; MD5=2efe269c0210a5ae48f5e89e102cfb3a; length=713; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(10637998..10638562,10638626..10638712,10638766..10639329,10639468..10639982,10640046..10640285,10640354..10640449,10640514..10640588); ID=FBpp0087375; name=CG11883-PB; parent=FBgn0033538,FBtr0088283; dbxref=GB_protein:AAF58768.1,FlyBase:FBpp0087375,FlyBase_Annotation_IDs:CG11883-PB,REFSEQ:NP_610598,GB_protein:AAF58768,FlyMine:FBpp0087375,modMine:FBpp0087375; MD5=2efe269c0210a5ae48f5e89e102cfb3a; length=713; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A8DY95, CG11883, isoform B OS=Drosophila melanogaster GN=CG11883 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0087375 type=protein; loc=2R:join(10637998..10638562,10638626..10638712,10638766..10639329,10639468..10639982,10640046..10640285,10640354..10640449,10640514..10640588); ID=FBpp0087375; name=CG11883-PB; parent=FBgn0033538,FBtr0088283; dbxref=GB_protein:AAF58768.1,FlyBase:FBpp0087375,FlyBase_Annotation_IDs:CG11883-PB,REFSEQ:NP_610598,GB_protein:AAF58768,FlyMine:FBpp0087375,modMine:FBpp0087375; MD5=2efe269c0210a5ae48f5e89e102cfb3a; length=713; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(10637998..10638562,10638626..10638712,10638766..10639329,10639468..10639982,10640046..10640285,10640354..10640449,10640514..10640588); ID=FBpp0087375; name=CG11883-PB; parent=FBgn0033538,FBtr0088283; dbxref=GB_protein:AAF58768.1,FlyBase:FBpp0087375,FlyBase_Annotation_IDs:CG11883-PB,REFSEQ:NP_610598,GB_protein:AAF58768,UniProt/TrEMBL:Q8T008,FlyMine:FBpp0087375,modMine:FBpp0087375; MD5=2efe269c0210a5ae48f5e89e102cfb3a; length=713; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 713 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nucleotide catabolic process [IEA]
    Molecular Function: 5'-nucleotidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQSSNPNFR SLDLSLGTPT PTTPTSSEIP AAPASATASL SGSTLQFGPE EPEEGSAAGG  60
   61 SQSLTPLDAR ELLTRPTRAY ASVSQPQSPR HRGSGCGSVS GSRIITHGLT GRSTSISSQL 120
  121 EKTKKLLKMT EGEDKPLTIL HYNDVYNIES MAETEPVGGA ARFATAIKSF AHLNPLVLFS 180
  181 GDAFSPSMLS TFTQGEQMIP VLNTVGTHCA VFGNHDFDHG LDVLVKLIKQ TEFPWLMSNV 240
  241 VDNETGRPLG GGKISHFILH NQISIGLIGL VEREWLETLP TIDPNEVTYI DYVEAGNKLA 300
  301 RELRNEGCDL IIALTHMRTP NDINLAEKCN GIDIILGGHD HVREVTEING KMIVKSGTDF 360
  361 QQFSVITIER DAANREHFTT DVKCFDVTAK IPEDPELKQE LSKYAKFIES KLSDVMGVFS 420
  421 VELDGRFSRV RTQETNLGNW VCDVVLAAVG ADVVILNGGT FRSDRVHPVG AFTMGDLVNV 480
  481 IPMRDPLILL EVKGKILWQA LENGVSAYPK LEGRFPQVSG ISFAFDPQAE PGKRIDPQLI 540
  541 QVGDEYLNLE QSYKLCVKSY IFMGCDGYTM FKDATVLMDD DACPELGITL QNHFKAINSR 600
  601 KCGQNTKHRQ SLVTLSRRHS LVQCLDSMDL DGPSPIRKLS VGHHNKSMDL THGNSQKMLR 660
  661 RASLDDLEQS TCDLAPQLEH RIVMIQNEEH HRQLLFKKET HIMNSTITEA EDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99] MSA 3.077994 View MSA. No confident structure predictions are available.
    2 View Details [100..612] PSI-BLAST 102.0 5'-NUCLEOTIDASE FROM E. COLI
    3 View Details [613..713] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  6.90309911517124 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.76617976580319 bayes_pls_golite062009
  • phosphatase activity
    		•  6.28072946025083 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.93537144836081 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  5.11265802430394 bayes_pls_golite062009
  • hydrolase activity
    		•  2.06280293513737 bayes_pls_golite062009
  • catalytic activity
    		•  1.39852585255405 bayes_pls_golite062009
  • binding
    		•  0.607014751804583 bayes_pls_golite062009
  • calcium-dependent protein serine/threonine phosphatase activity
    		•  0.598330833036731 bayes_pls_golite062009
  • protein kinase activity
    		•  0.55395641922978 bayes_pls_golite062009
  • signal transducer activity
    		•  0.541715460439478 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.541715460439478 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.395006104431866 bayes_pls_golite062009
  • kinase activity
    		•  0.366390322110727 bayes_pls_golite062009
  • protein binding
    		•  0.184079020957384 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.39246790349923E-4 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.72

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle