Protein Overview: CPTI-PA, CPTI-PB

General Information:
Name(s) found:	CPTI-PB / FBpp0087400 [FlyBase] CPTI-PA / FBpp0087399 [FlyBase]
Description(s) found: Found 36 descriptions. SHOW ALL	The gene mitochondrial carnitine palmitoyltransferase I is referred to in FlyBase by the symbol Dmel\CPTI (CG12891, FBgn0027842). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6356978..6366073. It has the cytological map location 47A9-47A11. Based on sequence similarity, it is predicted to have molecular function</span>: carnitine O-palmitoyltransferase activity. The biological processes in which it is involved are not known. 19 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene mitochondrial carnitine palmitoyltransferase I is referred to in FlyBase by the symbol Dmel\CPTI (CG12891, FBgn0027842). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6356978..6366073. It has the cytological map location 47A9-47A11. Based on sequence similarity, it is predicted to have molecular function</span>: carnitine O-palmitoyltransferase activity. The biological processes in which it is involved are not known. 19 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	780 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [ISS]
Biological Process:	NONE FOUND
Molecular Function:	carnitine O-palmitoyltransferase activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEAHAAVAF SFAITHEGFD INYDHEVLNL VWNSGVRSWK KRLARARNGV RNGVYPAHIQ  60
   61 SLWLISAIAL GLHFAGYQAP FNLTNRILVH LPSNTINWQV TACFLAALVV WLSICFTMRY 120
  121 TLKLLLMYKG WMYESRAPGS RVSLPTMLWV AVVRVLSSWN KPGLYSFQGS LPRLPLPSVK 180
  181 DTMTRYLRSV RPLLDDENYT RMERLAKEFE QTIGKKLQWY LILKSWWSTN YVSDWWEEYV 240
  241 YLRGRSPLCV NSNFYGTDAI FMNLTDKQAA RAANVISLLL NFRRLIEHQE LQPIMVQGMI 300
  301 PLCSWQYERT FNTARVPGLE TDRIIHYRDS NHIVVLHKGC YYKMLIYYKG RILRPCELQV 360
  361 QIEEILKGKA TPVEGEEHLA ALTAWNRSKW AEARNTFFSW GVNQTSLRTI ESAAFVLSLD 420
  421 DEPFEFDLAR PELLDNFGKK LLHGNGYNRW FDKCFTVCVG TNGRVGFNAE HTWADAPVLG 480
  481 HLWEYIFGDD IYGYDETGNT KGTPAFQPPT PTRLTWDLKP CLAQIEEATI DVTKLINEVN 540
  541 LRILVHQDYG KGFMKKCRIS PDAYIQMALQ LAYYRDAGRF SLTYEASMTR LFREGRTETV 600
  601 RPCTIESSAW VKAMQNPNTT NDERVKMMQA ACDRHQLGYQ DAMCGRGIDR HLFCLYVVSK 660
  661 YLEVDSPFLN EVLSEPWRLS TSQTPHGQTP KMDLKKHPNC ISAGGGFGPV ADDGYGVSYI 720
  721 IAGENLIFFH ISAKTTCQQT DVHRFAQNIS QALSDIRSMF EQHMKDHPKP AKSLTNGKST 780
  781

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
carnitine O-acyltransferase activity	7.54616819269984	bayes_pls_golite062009
carnitine O-acetyltransferase activity	7.38318207912192	bayes_pls_golite062009
choline O-acetyltransferase activity	6.09272417016149	bayes_pls_golite062009
octanoyltransferase activity	4.52268776339565	bayes_pls_golite062009
O-octanoyltransferase activity	4.52268776339565	bayes_pls_golite062009
carnitine O-octanoyltransferase activity	4.52268776339565	bayes_pls_golite062009
S-acyltransferase activity	4.44987112475286	bayes_pls_golite062009
carnitine O-palmitoyltransferase activity	3.83467723502092	bayes_pls_golite062009
O-palmitoyltransferase activity	3.83467723502092	bayes_pls_golite062009
transferase activity, transferring acyl groups	3.7327637835604	bayes_pls_golite062009
O-acyltransferase activity	3.7101056995294	bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity	3.56004160262054	bayes_pls_golite062009
dihydrolipoyllysine-residue acetyltransferase activity	3.36143851730669	bayes_pls_golite062009
S-acetyltransferase activity	3.32990830846882	bayes_pls_golite062009
acyltransferase activity	3.08588280042054	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	3.027770031317	bayes_pls_golite062009
S-succinyltransferase activity	3.02354522717247	bayes_pls_golite062009
dihydrolipoyllysine-residue succinyltransferase activity	3.02354522717247	bayes_pls_golite062009
O-acetyltransferase activity	2.37098434941789	bayes_pls_golite062009
palmitoyltransferase activity	2.23754077046213	bayes_pls_golite062009
succinyltransferase activity	2.08404693277798	bayes_pls_golite062009
choline binding	1.59193088660278	bayes_pls_golite062009
catalytic activity	1.51562638409295	bayes_pls_golite062009
acetyltransferase activity	1.12787027896966	bayes_pls_golite062009
transferase activity	1.08341671157927	bayes_pls_golite062009
binding	0.999555841397607	bayes_pls_golite062009
pyruvate dehydrogenase activity	0.85838145786229	bayes_pls_golite062009
protein binding	0.104367069798378	bayes_pls_golite062009
amine binding	0.0679262278252373	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..76]	MSA	2.030968	View MSA. No confident structure predictions are available.
2	View Details	[77..160]	MSA	1.103973	View MSA. No confident structure predictions are available.
3	View Details	[161..780]	PSI-BLAST	1000.0	Crystal structure of the M564G mutant of murine CrAT

Protein Overview: CPTI-PA, CPTI-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: