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Protein Overview: CG12896-PA

General Information:
Name(s) found: CG12896-PA / FBpp0087406 [FlyBase]
Description(s) found:
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  • gi|24652436|ref|NP_610584.2| CG12896 [Drosophila melanogaster] [NCBI NR]
  • gi|21627530|gb|AAF58796.2| CG12896 [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG12896 (CG12896, FBgn0033521). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6314385..6315418. It has the cytological map location 47A7. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: oxidoreductase activity; antioxidant activity. There is experimental evidence that it is involved in the biological process</span>: mesoderm development. No alleles are reported. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG12896-PA translation from_gene[CG12896 CG12896 FBgn0033521] seq_release:3 mol_weight=24757 cds_boundaries:(2R:5,487,605..5,488,452[-]) aa_length:220 transcript_info:[CG12896-RA seq_release:3] gene_info:[gene symbol:CG12896 FBgn0033521 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V5L0) CG12896 protein [DrosMelano7227.FASTAC.txt]
  • CG12896-PA [Drosophila melanogaster]gi|24652436|ref|NP_610584.2| CG12896-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(6314474..6314602,6314666..6314741,6314805..6315179,6315242..6315324); ID=FBpp0087406; name=CG12896-PA; parent=FBgn0033521,FBtr0088315; dbxref=FlyBase:FBpp0087406,FlyBase_Annotation_IDs:CG12896-PA,GB_protein:AAF58796.2,REFSE [fly-100309-contam.fasta]
  • CG12896-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(6314474..6314602,6314666..6314741,6314805..6315179,6315242..6315324); ID=FBpp0087406; name=CG12896-PA; parent=FBgn0033521,FBtr0088315; dbxref=FlyBase:FBpp0087406,FlyBase_Annotation_IDs:CG12896-PA,GB_protein:AAF58796.2,REFSEQ:NP_610584,GB_protein:AAF58796; MD5=8f425a76474af42c4b534d5ec856679e; length=220; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(6314474..6314602,6314666..6314741,6314805..6315179,6315242..6315324); ID=FBpp0087406; name=CG12896-PA; parent=FBgn0033521,FBtr0088315; dbxref=FlyBase:FBpp0087406,FlyBase_Annotation_IDs:CG12896-PA,GB_protein:AAF58796.2,REFSEQ:NP_610584,GB_protein:AAF58796; MD5=8f425a76474af42c4b534d5ec856679e; length=220; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG12896 OS=Drosophila melanogaster GN=CG12896-RA PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(6314474..6314602,6314666..6314741,6314805..6315179,6315242..6315324); ID=FBpp0087406; name=CG12896-PA; parent=FBgn0033521,FBtr0088315; dbxref=FlyBase:FBpp0087406,FlyBase_Annotation_IDs:CG12896-PA,GB_protein:AAF58796.2,REFSEQ:NP_610584,GB_protein:AAF58796,FlyMine:FBpp0087406,modMine:FBpp0087406; MD5=8f425a76474af42c4b534d5ec856679e; length=220; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(10427737..10427819,10427300..10427674,10427161..10427236,10426969..10427097)); ID=FBpp0087406; name=CG12896-PA; parent=FBgn0033521,FBtr0088315; dbxref=FlyBase:FBpp0087406,FlyBase_Annotation_IDs:CG12896-PA,GB_protein:AAF58796.2,REFSEQ:NP_610584,GB_protein:AAF58796,FlyMine:FBpp0087406,modMine:FBpp0087406; MD5=8f425a76474af42c4b534d5ec856679e; length=220; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(10427737..10427819,10427300..10427674,10427161..10427236,10426969..10427097)); ID=FBpp0087406; name=CG12896-PA; parent=FBgn0033521,FBtr0088315; dbxref=FlyBase:FBpp0087406,FlyBase_Annotation_IDs:CG12896-PA,GB_protein:AAF58796.2,REFSEQ:NP_610584,GB_protein:AAF58796,FlyMine:FBpp0087406,modMine:FBpp0087406; MD5=8f425a76474af42c4b534d5ec856679e; length=220; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0087406 type=protein; loc=2R:complement(join(10427737..10427819,10427300..10427674,10427161..10427236,10426969..10427097)); ID=FBpp0087406; name=CG12896-PA; parent=FBgn0033521,FBtr0088315; dbxref=FlyBase:FBpp0087406,FlyBase_Annotation_IDs:CG12896-PA,GB_protein:AAF58796.2,REFSEQ:NP_610584,GB_protein:AAF58796,FlyMine:FBpp0087406,modMine:FBpp0087406; MD5=8f425a76474af42c4b534d5ec856679e; length=220; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(10427737..10427819,10427300..10427674,10427161..10427236,10426969..10427097)); ID=FBpp0087406; name=CG12896-PA; parent=FBgn0033521,FBtr0088315; dbxref=FlyBase:FBpp0087406,FlyBase_Annotation_IDs:CG12896-PA,GB_protein:AAF58796.2,REFSEQ:NP_610584,GB_protein:AAF58796,UniProt/TrEMBL:A1Z893,FlyMine:FBpp0087406,modMine:FBpp0087406; MD5=8f425a76474af42c4b534d5ec856679e; length=220; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 220 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: mesoderm development [IEP]
    cell redox homeostasis [IEA]
    Molecular Function: antioxidant activity [IEA]
    oxidoreductase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLGQTVPNF EADTTKGPIK FHEWQGNSWV VLFSHPADFT PVCTTELGRI AVHQPEFAKR  60
   61 NTKCLAHSVD ALNSHVDWVN DIKSYCLDIP GDFPYPIIAD PTRDLAVTLG MLDEEQKKDP 120
  121 EVGKTIRALF IISPDHKVRL SMFYPMSTGR NVDEILRTID SLQLTDRLKV VATPANWTPG 180
  181 TKVMILPSVT DDEAHKLFPK GFDKVSMPSG VNYVRTTENY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..220] PSI-BLAST 54.045757 HorF6 peroxidase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • alkyl hydroperoxide reductase activity
    		•  4.29610283853788 bayes_pls_golite062009
  • antioxidant activity
    		•  3.8464796631544 bayes_pls_golite062009
  • peroxidase activity
    		•  3.43831566988273 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  3.43831566988273 bayes_pls_golite062009
  • selenium binding
    		•  2.92496040718744 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  2.56524997297011 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.30799114442278 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  2.23310780102446 bayes_pls_golite062009
  • peroxiredoxin activity
    		•  2.12777217096121 bayes_pls_golite062009
  • thioredoxin peroxidase activity
    		•  1.96134566495756 bayes_pls_golite062009
  • protein disulfide oxidoreductase activity
    		•  1.47769936616412 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  1.32811008894503 bayes_pls_golite062009
  • transferase activity
    		•  1.26687471229876 bayes_pls_golite062009
  • binding
    		•  1.25802922431343 bayes_pls_golite062009
  • protein binding
    		•  1.18479617596618 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.11518182894524 bayes_pls_golite062009
  • signal transducer activity
    		•  1.11518182894524 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • peptide binding
    		•  0.374493676068876 bayes_pls_golite062009
    		• 0.359224524631956 bayes_pls_golite062009
  • NADH dehydrogenase activity
    		•  0.23291471505999 bayes_pls_golite062009
  • copper ion binding
    		•  0.178842772364502 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  0.16328723676608 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  0.0434052164026002 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle