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Protein Overview: CAP-PC

General Information:
Name(s) found: CAP-PC / FBpp0087432 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6156528..6194529. It has the cytological map location 46F9-47A1. Based on sequence similarity, it is predicted to have molecular function</span>: vinculin binding. The biological processes in which it is involved are not known. 23 alleles are reported. No phenotypic data is available. It has 17 annotated transcripts and 17 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 824 amino acids

    Gene Ontology:
    Cellular Component: focal adhesion [ISS]
    Biological Process: NONE FOUND
    Molecular Function: vinculin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQEHTQSTT GTAMFAPKFK ARAPPGSGVW TPYGSSGDLN QSGATSATPP PPPPPSLPVW  60
   61 TPQPSPVLSG RKEFRPVRFE SPTLPRRYTA QQQQKTTTTI PPWSSAENGE GGPPPTAPAS 120
  121 LNSVNSNSDY AETDCSGHFG PVAPSASVSD KIRTFERSSS NSELQRPFVR RQLSDASRPA 180
  181 YRPNEVIYKV KHEYMSEPET GSDRPRKMAQ LGRRQYDGIG PVTNDGMPII LRSEVKEPHQ 240
  241 HEWYKRLYQT IHKQKNGDDF VIRYKCPRAR PSYKSNGYVS EPEPNYDSDY STVRYRTQNP 300
  301 HRVQSVSSAV NVRNLNQDEK LYGTMPNPIK SAQNSYKNQP GRIENYTTGH SSVSEKEKKE 360
  361 WWDEVMDIFN GNLEQSKLSP LYTEGNLSRA LAKESGYTSD SNLVFRKKEV PVSSPLSPVE 420
  421 QKQAYKSLQA GGEPPLLGFR KPAPEKPRDL DPNAPPIPPQ PPVKGLSSYD FPYSTDTVDG 480
  481 SDVNIHFKTP IRHEQRQNLS EEELAIRQAE HMQKLYHEER RRKYLQELQD MNSRRHTDNF 540
  541 TPSQKSPIAL NRYDDFPTDV TLKSLVGPKT VARALFNFQG QTSKELSFRK GDTIYIRRQI 600
  601 DANWYEGEHN AMIGLLPASY VEIVSRDGAR TPSKRPSEGQ ARAKYNFQAQ SGIELSLNKG 660
  661 ELVTLTRRVD GNWFEGKIAN RKGIFPCSYV EVLTDIGAED IAARTTTVIT SQSTTNLRPN 720
  721 LDVLRTNINN EFNTLTQNGA QPPNGILKET RTLHKTDALH VDTSSEPLAY RALYKYRPQN 780
  781 SDELELLEGD VVHVLEKCDD GWFVGTSQRT GCFGTFPGNY VERA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..136] MSA 1.211992 View MSA. No confident structure predictions are available.
    2 View Details [137..334] MSA 4.226986 View MSA. No confident structure predictions are available.
    3 View Details [335..489] deduced N/A No confident structure predictions are available.
    4 View Details [490..752] PSI-BLAST 8.69897 Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
    5 View Details [753..824] PSI-BLAST 33.69897 Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.13376047180398 bayes_pls_golite062009
  • protein binding
    		•  1.03382488697656 bayes_pls_golite062009
  • signal transducer activity
    		•  0.69727426993974 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.69727426993974 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle