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View Structure Prediction Details

Protein: CAP-PC
Organism: Drosophila melanogaster
Length: 824 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAP-PC.

Description E-value Query
Range
Subject
Range
gi|14669818 - gi|14669818|dbj|BAB62019.1| DCAPL3 [Drosophila melanogaster]
350.0 [0..1] [824..1]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQEHTQSTT GTAMFAPKFK ARAPPGSGVW TPYGSSGDLN QSGATSATPP PPPPPSLPVW  60
   61 TPQPSPVLSG RKEFRPVRFE SPTLPRRYTA QQQQKTTTTI PPWSSAENGE GGPPPTAPAS 120
  121 LNSVNSNSDY AETDCS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [137-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHFGPVAPSA SVSDKIRTFE RSSSNSELQR PFVRRQLSDA SRPAYRPNEV IYKVKHEYMS  60
   61 EPETGSDRPR KMAQLGRRQY DGIGPVTNDG MPIILRSEVK EPHQHEWYKR LYQTIHKQKN 120
  121 GDDFVIRYKC PRARPSYKSN GYVSEPEPNY DSDYSTVRYR TQNPHRVQSV SSAVNVRNLN 180
  181 QDEKLYGTMP NPIKSAQN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [335-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYKNQPGRIE NYTTGHSSVS EKEKKEWWDE VMDIFNGNLE QSKLSPLYTE GNLSRALAKE  60
   61 SGYTSDSNLV FRKKEVPVSS PLSPVEQKQA YKSLQAGGEP PLLGFRKPAP EKPRDLDPNA 120
  121 PPIPPQPPVK GLSSYDFPYS TDTVDGSDVN IHFKT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [490-752]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIRHEQRQNL SEEELAIRQA EHMQKLYHEE RRRKYLQELQ DMNSRRHTDN FTPSQKSPIA  60
   61 LNRYDDFPTD VTLKSLVGPK TVARALFNFQ GQTSKELSFR KGDTIYIRRQ IDANWYEGEH 120
  121 NAMIGLLPAS YVEIVSRDGA RTPSKRPSEG QARAKYNFQA QSGIELSLNK GELVTLTRRV 180
  181 DGNWFEGKIA NRKGIFPCSY VEVLTDIGAE DIAARTTTVI TSQSTTNLRP NLDVLRTNIN 240
  241 NEFNTLTQNG AQPPNGILKE TRT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1oplA
Description: Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13376047180398 bayes_pls_golite062009
protein binding 1.03382488697656 bayes_pls_golite062009
signal transducer activity 0.69727426993974 bayes_pls_golite062009
molecular transducer activity 0.69727426993974 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [753-824]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHKTDALHVD TSSEPLAYRA LYKYRPQNSD ELELLEGDVV HVLEKCDDGW FVGTSQRTGC  60
   61 FGTFPGNYVE RA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle