Protein Overview: CAP-PA

General Information:
Name(s) found:	CAP-PA / FBpp0087430 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24652386\|ref\|NP_610571.2\| CAP, isoform A [Drosophila melanogaster] [NCBI NR] gi\|21627574\|gb\|AAF58816.2\| CAP, isoform A [Drosophila melanogaster] [NCBI NR] The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6156528..6194529. It has the cytological map location 46F9-47A1. Based on sequence similarity, it is predicted to have molecular function</span>: vinculin binding. The biological processes in which it is involved are not known. 23 alleles are reported. No phenotypic data is available. It has 17 annotated transcripts and 17 annotated polypeptides. [FlyBase] >CG18408-PA translation from_gene[CG18408 rexin FBgn0033504] seq_release:3 mol_weight=267670 cds_boundaries:(2R:5,339,974..5,366,943[+]) aa_length:2376 transcript_info:[CG18408-RA seq_release:3] gene_info:[gene symbol:rexin synonyms:[CG3451 CG18409] FB [hmr_yeast5_DM3-1_pombe.fasta] (Q9V5J0) CG18408 protein [DrosMelano7227.FASTAC.txt] CG18408-PA, isoform A [Drosophila melanogaster]gi\|24652386\|ref\|NP_610571.2\| CG18408-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2R:join(6166846..6172306,6182117..6182270,6182351..6182471,6182796..6182828,6183247..6183299,6183374..6183552,6187995..6188093,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087430; name=CA [fly-100309-contam.fasta] CAP CG18408-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG18408-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:join(6166846..6172306,6182117..6182270,6182351..6182471,6182796..6182828,6183247..6183299,6183374..6183552,6187995..6188093,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087430; name=CAP-PA; parent=FBgn0033504,FBtr0088341; dbxref=FlyBase:FBpp0087430,FlyBase_Annotation_IDs:CG18408-PA,GB_protein:AAF58816.2,REFSEQ:NP_610571,GB_protein:AAF58816; MD5=2231fa90b5b2c68bc815ca6f6babc9e4; length=2376; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:join(6166846..6172306,6182117..6182270,6182351..6182471,6182796..6182828,6183247..6183299,6183374..6183552,6187995..6188093,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087430; name=CAP-PA; parent=FBgn0033504,FBtr0088341; dbxref=FlyBase:FBpp0087430,FlyBase_Annotation_IDs:CG18408-PA,GB_protein:AAF58816.2,REFSEQ:NP_610571,GB_protein:AAF58816; MD5=2231fa90b5b2c68bc815ca6f6babc9e4; length=2376; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] CAP, isoform A OS=Drosophila melanogaster GN=CAP PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2R:join(6166846..6172306,6182117..6182270,6182351..6182471,6182796..6182828,6183247..6183299,6183374..6183552,6187995..6188093,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087430; name=CAP-PA; parent=FBgn0033504,FBtr0088341; dbxref=FlyBase:FBpp0087430,FlyBase_Annotation_IDs:CG18408-PA,GB_protein:AAF58816.2,REFSEQ:NP_610571,GB_protein:AAF58816,FlyMine:FBpp0087430,modMine:FBpp0087430; MD5=2231fa90b5b2c68bc815ca6f6babc9e4; length=2376; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2R:join(10279341..10284801,10294612..10294765,10294846..10294966,10295291..10295323,10295742..10295794,10295869..10296047,10300490..10300588,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087430; name=CAP-PA; parent=FBgn0033504,FBtr0088341; dbxref=FlyBase:FBpp0087430,FlyBase_Annotation_IDs:CG18408-PA,GB_protein:AAF58816.2,REFSEQ:NP_610571,GB_protein:AAF58816,FlyMine:FBpp0087430,modMine:FBpp0087430; MD5=2231fa90b5b2c68bc815ca6f6babc9e4; length=2376; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:join(10279341..10284801,10294612..10294765,10294846..10294966,10295291..10295323,10295742..10295794,10295869..10296047,10300490..10300588,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087430; name=CAP-PA; parent=FBgn0033504,FBtr0088341; dbxref=FlyBase:FBpp0087430,FlyBase_Annotation_IDs:CG18408-PA,GB_protein:AAF58816.2,REFSEQ:NP_610571,GB_protein:AAF58816,FlyMine:FBpp0087430,modMine:FBpp0087430; MD5=2231fa90b5b2c68bc815ca6f6babc9e4; length=2376; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of A0A0B4K7L3, CAP, isoform A OS=Drosophila melanogaster GN=CAP PE=1 SV=1 [DROME.fasta.20160308] FBpp0087430 type=protein; loc=2R:join(10279341..10284801,10294612..10294765,10294846..10294966,10295291..10295323,10295742..10295794,10295869..10296047,10300490..10300588,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087430; name=CAP-PA; parent=FBgn0033504,FBtr0088341; dbxref=FlyBase:FBpp0087430,FlyBase_Annotation_IDs:CG18408-PA,GB_protein:AAF58816.2,REFSEQ:NP_610571,GB_protein:AAF58816,FlyMine:FBpp0087430,modMine:FBpp0087430; MD5=2231fa90b5b2c68bc815ca6f6babc9e4; length=2376; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:join(10279341..10284801,10294612..10294765,10294846..10294966,10295291..10295323,10295742..10295794,10295869..10296047,10300490..10300588,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087430; name=CAP-PA; parent=FBgn0033504,FBtr0088341; dbxref=FlyBase:FBpp0087430,FlyBase_Annotation_IDs:CG18408-PA,GB_protein:AAF58816.2,REFSEQ:NP_610571,GB_protein:AAF58816,UniProt/TrEMBL:A1Z867,FlyMine:FBpp0087430,modMine:FBpp0087430; MD5=2231fa90b5b2c68bc815ca6f6babc9e4; length=2376; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	2376 amino acids
Gene Ontology:
Cellular Component:	focal adhesion [ISS]
Biological Process:	NONE FOUND
Molecular Function:	vinculin binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNNRNRNRN RNRNKRNRNQ NQNQNPSQNQ NENHQQQAEG AEDREEQQDF QTQIAVAQSS  60
   61 SFVDDNGNSG SVSNGPTENS EEVTNTLEKT EKKEEIFEQP ATVIQKEADS DAEMGAKNSK 120
  121 HRKEKSDKQA SNGKSEEQVR PPPTIIRRPP GSPRQAKVIV HRIVREEDTA NGKAQSPEPP 180
  181 KAVESKEQHM EVEDSKKEKP EAQQEIETKE ERENEPSPKE LPESSHLSED AQQKHVEVEE 240
  241 NQQVYDEVDY SKDETTDNNP QQEQHDSKEP EQYVLQLEKA MEFVENAHQQ HVAAVQSYQK 300
  301 QRDTEQNAQQ QEQNEAQHLQ ESTKAHQQNI AVPQILVDPK KREEGLAQQL HHDVKEEPIL 360
  361 NNAQQQNDDT APKSPKEVTI KVQFQTEDPY SQQPPPQKPT SKVIIHQIHV ETTDEEQNAK 420
  421 PTFEEVSSTT GSLAGTLSPP PRYLVESPKN VSSGQFSNFS RNVQIQEMEL NSDFSSGEFN 480
  481 SLQSPLVCEV DSESEGSVVL GPERSPSDQQ VPSSSRVEQH EQVRQKRAQY RNALESHFMP 540
  541 QLLNPRYLDS ILEENEWRNS TASSGGSDQT GIRTPKLNET FPRSQLDFSR RHKRREEAPS 600
  601 PLKLETKLLE ESTDLESCTR LQSALSPQSE DAELVYLSSS ASSSVSDLME LELEQAAALA 660
  661 ERALVDLDTD ASRLIARPDD EMSSTSTTTA DRSETEAETE TETEREGEQS RESTPVNANP 720
  721 TLASSQSSLL SAATPTPTPT PTPADREQLA KDTNVSGGST VSFGAASPLA ATREEFVRNM 780
  781 DKVRELIEMT RREQEQGELP RSPSPPPVPP PPASVPPYSP ESSSFHLASL QLKRQESNDS 840
  841 HCSDSTTHSQ CTAINLASPP PPPTAQPPTP PLRQKPAPPP VPQPVSPPAP PTPQSEPELS 900
  901 VADSVANANA DVDADADTDT EAIKKLRLLC TEQLASMPYG EQVLEELASV AQNISDQSQN 960
  961 KMPYPMPQLP HIKELQLNAN ESKSSSAWLG LPTQSDPKLL VCLSPGQRDL VNNQTQPDDL1020
 1021 LDAHQKFVER RGYHELSKAQ VLEQDHQQQQ SEMLKTAAMM RELRKSLSPP APPVPPPPVP1080
 1081 VKSAETAAKA TAHENAKRDD ASEQKQKIAA CESSSLENKP RRAADLGAQQ SAEQRQSSST1140
 1141 TTSSHKATTE TMSSDTAKFP TLDSMESELA RMFPQHKGDI FEEQRKRFSN IEFPSHQPVS1200
 1201 QTKRYSNIET SSYESKKRME NGQVVYDVST SSHEKKEQGD PPKDQPVPPV PPPPIMSATK1260
 1261 LNGNTFIDGD VAPKNSQPSR ESGSGSGNGT YEEFRQRAKA AADAFGEQRE QQNGLDQDRV1320
 1321 FKDFDRLSQQ MHAELQSTRE KREKSASMYD LSGFTRPASG HPRLDELQQR RHAHMQELER1380
 1381 EIERSAKSRQ ERMSSVPRQM EATPPRTHEI PIELEPRSRR AESLCNLNEP PPRPHTTVGH1440
 1441 YNHPVVQDDW SRYANDLGYS ENIARPFARE VEICYQRQNQ RTPHCIRAPR LSASTNDLSS1500
 1501 SSQYSYDTFN AYGGRRTHAP MLNQAQQQQR PHYGSCYSMI ERDPNPRYIS TTSRRGVSPA1560
 1561 PPPVATPQQQ QVPPPAYDRQ QRRSSLPREL HEQQLKYILS KEEELKFEVE RLQQERRRLM1620
 1621 EEMQRAPVLP APQRRESYRP AAKLPTLSED EVFRQQMAEE WMNKVAEREE RRQHKIIRIS1680
 1681 KIEDEHDHSA VDKATISDEF LDRVKERRHK LSMPADSDWE SGAESQPQPA AQSQPESDVE1740
 1741 APPVRILEGQ AEANLRQLPR HLREFAKFST SEQLPDGAQM ERHEEQERRE EATDNAHSSA1800
 1801 TKKTSIVKTY KVSRLPPSVQ ARPSYKSNGY VSEPEPNYDS DYSTVRYRTQ NPHRVQSVSS1860
 1861 AVNVRNLNQD EKLYGTMPNP IKSAQNSYKN QPGRIENYTT GHSSVSEKEK KEWWDEVMDI1920
 1921 FNGNLEQSKL SPLYTEGNLS RALAKESGYT SDSNLVFRKK EVPVSSPLSP VEQKQAYKSL1980
 1981 QAGGEPPLLG FRKPAPEKPR DLDPNAPPIP PQPPVKGLSS YDFPYSTDTV DGSDVNIHFK2040
 2041 TPIRHEQRQN LSEEELAIRQ AEHMQKLYHE ERRRKYLQEL QDMNSRRHTD NFTPSQKSPI2100
 2101 ALNRYDDFPT DVTLKSLVGP KTVARALFNF QGQTSKELSF RKGDTIYIRR QIDANWYEGE2160
 2161 HNAMIGLLPA SYVEIVSRDG ARTPSKRPSE GQARAKYNFQ AQSGIELSLN KGELVTLTRR2220
 2221 VDGNWFEGKI ANRKGIFPCS YVEVLTDIGA EDIAARTTTV ITSQSTTNLR PNLDVLRTNI2280
 2281 NNEFNTLTQN GAQPPNGILK ETRTLHKTDA LHVDTSSEPL AYRALYKYRP QNSDELELLE2340
 2341 GDVVHVLEKC DDGWFVGTSQ RTGCFGTFPG NYVERA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..127]	deduced	N/A	No confident structure predictions are available.
2	View Details	[128..353]	deduced	N/A	No confident structure predictions are available.
3	View Details	[354..457]	deduced	N/A	No confident structure predictions are available.
4	View Details	[458..564]	deduced	N/A	No confident structure predictions are available.
5	View Details	[565..758]	deduced	N/A	No confident structure predictions are available.
6	View Details	[759..831]	deduced	N/A	No confident structure predictions are available.
7	View Details	[832..882]	deduced	N/A	No confident structure predictions are available.
8	View Details	[883..1031]	deduced	N/A	No confident structure predictions are available.
9	View Details	[1032..1242]	deduced	N/A	No confident structure predictions are available.
10	View Details	[1243..1358]	deduced	N/A	No confident structure predictions are available.
11	View Details	[1359..1448]	deduced	N/A	No confident structure predictions are available.
12	View Details	[1449..1528]	deduced	N/A	No confident structure predictions are available.
13	View Details	[1529..1733]	deduced	N/A	No confident structure predictions are available.
14	View Details	[1734..1919]	deduced	N/A	No confident structure predictions are available.
15	View Details	[1920..2110]	deduced	N/A	No confident structure predictions are available.
16	View Details	[2111..2185]	PSI-BLAST	24.522879	p47pox (neutrophil cytosolic factor 1)
17	View Details	[2186..2376]	PSI-BLAST	32.69897	Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: CAP-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: