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Protein Overview: CAP-PH, CAP-PG

General Information:
Name(s) found: CAP-PG / FBpp0087429 [FlyBase]
CAP-PH / FBpp0087428 [FlyBase]
Description(s) found:
Found 35 descriptions.
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  • The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6156528..6194529. It has the cytological map location 46F9-47A1. Based on sequence similarity, it is predicted to have molecular function</span>: vinculin binding. The biological processes in which it is involved are not known. 23 alleles are reported. No phenotypic data is available. It has 17 annotated transcripts and 17 annotated polypeptides. [FlyBase]
  • The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6156528..6194529. It has the cytological map location 46F9-47A1. Based on sequence similarity, it is predicted to have molecular function</span>: vinculin binding. The biological processes in which it is involved are not known. 23 alleles are reported. No phenotypic data is available. It has 17 annotated transcripts and 17 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 500 amino acids

    Gene Ontology:
    Cellular Component: focal adhesion [ISS]
    Biological Process: NONE FOUND
    Molecular Function: vinculin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNPIKSAQN SYKNQPGRIE NYTTGHSSVS EKEKKEWWDE VMDIFNGNLE QSKLSPLYTE  60
   61 GNLSRALAKE SGYTSDSNLV FRKKEVPVSS PLSPVEQKQA YKSLQAGGEP PLLGFRKPAP 120
  121 EKPRDLDPNA PPIPPQPPVK GLSSYDFPYS TDTVDGSDVN IHFKTPIRHE QRQNLSEEEL 180
  181 AIRQAEHMQK LYHEERRRKY LQELQDMNSR RHTDNFTPSQ KSPIALNRYD DFPTDVTLKS 240
  241 LVGPKTVARA LFNFQGQTSK ELSFRKGDTI YIRRQIDANW YEGEHNAMIG LLPASYVEIV 300
  301 SRDGARTPSK RPSEGQARAK YNFQAQSGIE LSLNKGELVT LTRRVDGNWF EGKIANRKGI 360
  361 FPCSYVEVLT DIGAEDIAAR TTTVITSQST TNLRPNLDVL RTNINNEFNT LTQNGAQPPN 420
  421 GILKETRTLH KTDALHVDTS SEPLAYRALY KYRPQNSDEL ELLEGDVVHV LEKCDDGWFV 480
  481 GTSQRTGCFG TFPGNYVERA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] MSA 1.190993 View MSA. No confident structure predictions are available.
    2 View Details [136..245] PSI-BLAST 13.09691 Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
    3 View Details [246..500] PSI-BLAST 35.154902 Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • signal transducer activity
    		•  0.69727426993974 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle