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View Structure Prediction Details

Protein: CAP-PH, CAP-PG
Organism: Drosophila melanogaster
Length: 500 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAP-PH, CAP-PG.

Description E-value Query
Range
Subject
Range
gi|220950558 - gi|220950558|gb|ACL87822.1| CAP-PE [synthetic construct]
CAP-PI - The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protei...
307.0 [0..1] [500..140]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNPIKSAQN SYKNQPGRIE NYTTGHSSVS EKEKKEWWDE VMDIFNGNLE QSKLSPLYTE  60
   61 GNLSRALAKE SGYTSDSNLV FRKKEVPVSS PLSPVEQKQA YKSLQAGGEP PLLGFRKPAP 120
  121 EKPRDLDPNA PPIPP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPPVKGLSSY DFPYSTDTVD GSDVNIHFKT PIRHEQRQNL SEEELAIRQA EHMQKLYHEE  60
   61 RRRKYLQELQ DMNSRRHTDN FTPSQKSPIA LNRYDDFPTD VTLKSLVGPK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.09691
Match: 1oplA
Description: Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [246-500]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVARALFNFQ GQTSKELSFR KGDTIYIRRQ IDANWYEGEH NAMIGLLPAS YVEIVSRDGA  60
   61 RTPSKRPSEG QARAKYNFQA QSGIELSLNK GELVTLTRRV DGNWFEGKIA NRKGIFPCSY 120
  121 VEVLTDIGAE DIAARTTTVI TSQSTTNLRP NLDVLRTNIN NEFNTLTQNG AQPPNGILKE 180
  181 TRTLHKTDAL HVDTSSEPLA YRALYKYRPQ NSDELELLEG DVVHVLEKCD DGWFVGTSQR 240
  241 TGCFGTFPGN YVERA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.154902
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
signal transducer activity 0.69727426993974 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle