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Protein Overview: CAP-PI

General Information:
Name(s) found: CAP-PI / FBpp0087427 [FlyBase]
Description(s) found:
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  • gi|24652384|ref|NP_610570.1| CAP, isoform I [Drosophila melanogaster] [NCBI NR]
  • gi|21627573|gb|AAF58813.2| CAP, isoform I [Drosophila melanogaster] [NCBI NR]
  • The gene CAP is referred to in FlyBase by the symbol Dmel\CAP (CG18408, FBgn0033504). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6156528..6194529. It has the cytological map location 46F9-47A1. Based on sequence similarity, it is predicted to have molecular function</span>: vinculin binding. The biological processes in which it is involved are not known. 23 alleles are reported. No phenotypic data is available. It has 17 annotated transcripts and 17 annotated polypeptides. [FlyBase]
  • >CG18408-PI translation from_gene[CG18408 rexin FBgn0033504] seq_release:3 mol_weight=72032 cds_boundaries:(2R:5,329,681..5,366,943[+]) aa_length:639 transcript_info:[CG18408-RI seq_release:3] gene_info:[gene symbol:rexin synonyms:[CG3451 CG18409] FBgn [hmr_yeast5_DM3-1_pombe.fasta]
  • (AAF58813) CG18408-PI [DrosMelano7227.FASTAC.txt]
  • CG18408-PI, isoform I [Drosophila melanogaster]gi|24652384|ref|NP_610570.1| CG18408-PI [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(6156553..6156621,6156767..6156867,6156927..6157006,6182117..6182270,6182351..6182471,6182796..6182828,6183247..6183299,6183374..6183552,6187995..6188093,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650. [fly-100309-contam.fasta]
  • CAP CG18408-PI, isoform I [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG18408-PI, isoform I [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(6156553..6156621,6156767..6156867,6156927..6157006,6182117..6182270,6182351..6182471,6182796..6182828,6183247..6183299,6183374..6183552,6187995..6188093,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087427; name=CAP-PI; parent=FBgn0033504,FBtr0088338; dbxref=FlyBase:FBpp0087427,FlyBase_Annotation_IDs:CG18408-PI,GB_protein:AAF58813.2,REFSEQ:NP_610570,GB_protein:AAF58813; MD5=84758f73addebd1cc458056a69c2d733; length=639; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(6156553..6156621,6156767..6156867,6156927..6157006,6182117..6182270,6182351..6182471,6182796..6182828,6183247..6183299,6183374..6183552,6187995..6188093,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087427; name=CAP-PI; parent=FBgn0033504,FBtr0088338; dbxref=FlyBase:FBpp0087427,FlyBase_Annotation_IDs:CG18408-PI,GB_protein:AAF58813.2,REFSEQ:NP_610570,GB_protein:AAF58813; MD5=84758f73addebd1cc458056a69c2d733; length=639; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CAP, isoform I OS=Drosophila melanogaster GN=CAP PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(6156553..6156621,6156767..6156867,6156927..6157006,6182117..6182270,6182351..6182471,6182796..6182828,6183247..6183299,6183374..6183552,6187995..6188093,6192129..6192435,6192493..6192607,6192977..6193183,6193243..6193475,6193650..6193818); ID=FBpp0087427; name=CAP-PI; parent=FBgn0033504,FBtr0088338; dbxref=FlyBase:FBpp0087427,FlyBase_Annotation_IDs:CG18408-PI,GB_protein:AAF58813.2,REFSEQ:NP_610570,GB_protein:AAF58813,FlyMine:FBpp0087427,modMine:FBpp0087427; MD5=84758f73addebd1cc458056a69c2d733; length=639; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • CAP, isoform I OS=Drosophila melanogaster GN=CAP PE=4 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2R:join(10269048..10269116,10269262..10269362,10269422..10269501,10294612..10294765,10294846..10294966,10295291..10295323,10295742..10295794,10295869..10296047,10300490..10300588,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087427; name=CAP-PI; parent=FBgn0033504,FBtr0088338; dbxref=FlyBase:FBpp0087427,FlyBase_Annotation_IDs:CG18408-PI,GB_protein:AAF58813.2,REFSEQ:NP_610570,GB_protein:AAF58813,FlyMine:FBpp0087427,modMine:FBpp0087427; MD5=84758f73addebd1cc458056a69c2d733; length=639; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(10269048..10269116,10269262..10269362,10269422..10269501,10294612..10294765,10294846..10294966,10295291..10295323,10295742..10295794,10295869..10296047,10300490..10300588,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087427; name=CAP-PI; parent=FBgn0033504,FBtr0088338; dbxref=FlyBase:FBpp0087427,FlyBase_Annotation_IDs:CG18408-PI,GB_protein:AAF58813.2,REFSEQ:NP_610570,GB_protein:AAF58813,FlyMine:FBpp0087427,modMine:FBpp0087427; MD5=84758f73addebd1cc458056a69c2d733; length=639; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A0A0B4K7L3, CAP, isoform I OS=Drosophila melanogaster GN=CAP PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0087427 type=protein; loc=2R:join(10269048..10269116,10269262..10269362,10269422..10269501,10294612..10294765,10294846..10294966,10295291..10295323,10295742..10295794,10295869..10296047,10300490..10300588,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087427; name=CAP-PI; parent=FBgn0033504,FBtr0088338; dbxref=FlyBase:FBpp0087427,FlyBase_Annotation_IDs:CG18408-PI,GB_protein:AAF58813.2,REFSEQ:NP_610570,GB_protein:AAF58813,FlyMine:FBpp0087427,modMine:FBpp0087427; MD5=84758f73addebd1cc458056a69c2d733; length=639; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(10269048..10269116,10269262..10269362,10269422..10269501,10294612..10294765,10294846..10294966,10295291..10295323,10295742..10295794,10295869..10296047,10300490..10300588,10304624..10304930,10304988..10305102,10305472..10305678,10305738..10305970,10306145..10306313); ID=FBpp0087427; name=CAP-PI; parent=FBgn0033504,FBtr0088338; dbxref=FlyBase:FBpp0087427,FlyBase_Annotation_IDs:CG18408-PI,GB_protein:AAF58813.2,REFSEQ:NP_610570,GB_protein:AAF58813,UniProt/TrEMBL:A1Z866,FlyMine:FBpp0087427,modMine:FBpp0087427; MD5=84758f73addebd1cc458056a69c2d733; length=639; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 639 amino acids

    Gene Ontology:
    Cellular Component: focal adhesion [ISS]
    Biological Process: NONE FOUND
    Molecular Function: vinculin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKFCSLRRS KEPAIVAPKV AKSSSLRLKD VPLNDAQLLQ VLHAQRERGP LILALSSAKN  60
   61 SVQTCRKCGT PYENRQVVEN GTTARPSYKS NGYVSEPEPN YDSDYSTVRY RTQNPHRVQS 120
  121 VSSAVNVRNL NQDEKLYGTM PNPIKSAQNS YKNQPGRIEN YTTGHSSVSE KEKKEWWDEV 180
  181 MDIFNGNLEQ SKLSPLYTEG NLSRALAKES GYTSDSNLVF RKKEVPVSSP LSPVEQKQAY 240
  241 KSLQAGGEPP LLGFRKPAPE KPRDLDPNAP PIPPQPPVKG LSSYDFPYST DTVDGSDVNI 300
  301 HFKTPIRHEQ RQNLSEEELA IRQAEHMQKL YHEERRRKYL QELQDMNSRR HTDNFTPSQK 360
  361 SPIALNRYDD FPTDVTLKSL VGPKTVARAL FNFQGQTSKE LSFRKGDTIY IRRQIDANWY 420
  421 EGEHNAMIGL LPASYVEIVS RDGARTPSKR PSEGQARAKY NFQAQSGIEL SLNKGELVTL 480
  481 TRRVDGNWFE GKIANRKGIF PCSYVEVLTD IGAEDIAART TTVITSQSTT NLRPNLDVLR 540
  541 TNINNEFNTL TQNGAQPPNG ILKETRTLHK TDALHVDTSS EPLAYRALYK YRPQNSDELE 600
  601 LLEGDVVHVL EKCDDGWFVG TSQRTGCFGT FPGNYVERA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] MSA 5.190996 View MSA. No confident structure predictions are available.
    2 View Details [153..380] deduced N/A No confident structure predictions are available.
    3 View Details [381..444] PSI-BLAST 16.221849 p47pox (neutrophil cytosolic factor 1)
    4 View Details [445..639] PSI-BLAST 24.30103 Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.13376047180398 bayes_pls_golite062009
  • protein binding
    		•  1.03382488697656 bayes_pls_golite062009
  • signal transducer activity
    		•  0.69727426993974 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.69727426993974 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle