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View Structure Prediction Details

Protein: CAP-PI
Organism: Drosophila melanogaster
Length: 639 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAP-PI.

Description E-value Query
Range
Subject
Range
gi|25012702 - gi|25012702|gb|AAN71445.1| RE58362p [Drosophila melanogaster]
368.0 [0..1] [639..9]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKFCSLRRS KEPAIVAPKV AKSSSLRLKD VPLNDAQLLQ VLHAQRERGP LILALSSAKN  60
   61 SVQTCRKCGT PYENRQVVEN GTTARPSYKS NGYVSEPEPN YDSDYSTVRY RTQNPHRVQS 120
  121 VSSAVNVRNL NQDEKLYGTM PNPIKSAQNS YK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [153-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQPGRIENYT TGHSSVSEKE KKEWWDEVMD IFNGNLEQSK LSPLYTEGNL SRALAKESGY  60
   61 TSDSNLVFRK KEVPVSSPLS PVEQKQAYKS LQAGGEPPLL GFRKPAPEKP RDLDPNAPPI 120
  121 PPQPPVKGLS SYDFPYSTDT VDGSDVNIHF KTPIRHEQRQ NLSEEELAIR QAEHMQKLYH 180
  181 EERRRKYLQE LQDMNSRRHT DNFTPSQKSP IALNRYDDFP TDVTLKSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [381-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGPKTVARAL FNFQGQTSKE LSFRKGDTIY IRRQIDANWY EGEHNAMIGL LPASYVEIVS  60
   61 RDGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.221849
Match: 1uecA
Description: p47pox (neutrophil cytosolic factor 1)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [445-639]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTPSKRPSEG QARAKYNFQA QSGIELSLNK GELVTLTRRV DGNWFEGKIA NRKGIFPCSY  60
   61 VEVLTDIGAE DIAARTTTVI TSQSTTNLRP NLDVLRTNIN NEFNTLTQNG AQPPNGILKE 120
  121 TRTLHKTDAL HVDTSSEPLA YRALYKYRPQ NSDELELLEG DVVHVLEKCD DGWFVGTSQR 180
  181 TGCFGTFPGN YVERA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.30103
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13376047180398 bayes_pls_golite062009
protein binding 1.03382488697656 bayes_pls_golite062009
signal transducer activity 0.69727426993974 bayes_pls_golite062009
molecular transducer activity 0.69727426993974 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle