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View Structure Prediction Details

Protein: CAP-PI
Organism: Drosophila melanogaster
Length: 639 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAP-PI.

Description E-value Query
Range
Subject
Range
gi|25012702 - gi|25012702|gb|AAN71445.1| RE58362p [Drosophila melanogaster]
368.0 [0..1] [639..9]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKFCSLRRS KEPAIVAPKV AKSSSLRLKD VPLNDAQLLQ VLHAQRERGP LILALSSAKN  60
   61 SVQTCRKCGT PYENRQVVEN GTTARPSYKS NGYVSEPEPN YDSDYSTVRY RTQNPHRVQS 120
  121 VSSAVNVRNL NQDEKLYGTM PNPIKSAQNS YK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [153-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQPGRIENYT TGHSSVSEKE KKEWWDEVMD IFNGNLEQSK LSPLYTEGNL SRALAKESGY  60
   61 TSDSNLVFRK KEVPVSSPLS PVEQKQAYKS LQAGGEPPLL GFRKPAPEKP RDLDPNAPPI 120
  121 PPQPPVKGLS SYDFPYSTDT VDGSDVNIHF KTPIRHEQRQ NLSEEELAIR QAEHMQKLYH 180
  181 EERRRKYLQE LQDMNSRRHT DNFTPSQKSP IALNRYDDFP TDVTLKSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [381-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGPKTVARAL FNFQGQTSKE LSFRKGDTIY IRRQIDANWY EGEHNAMIGL LPASYVEIVS  60
   61 RDGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.221849
Match: 1uecA
Description: p47pox (neutrophil cytosolic factor 1)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [445-639]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTPSKRPSEG QARAKYNFQA QSGIELSLNK GELVTLTRRV DGNWFEGKIA NRKGIFPCSY  60
   61 VEVLTDIGAE DIAARTTTVI TSQSTTNLRP NLDVLRTNIN NEFNTLTQNG AQPPNGILKE 120
  121 TRTLHKTDAL HVDTSSEPLA YRALYKYRPQ NSDELELLEG DVVHVLEKCD DGWFVGTSQR 180
  181 TGCFGTFPGN YVERA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.30103
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.13376047180398 bayes_pls_golite062009
protein binding 1.03382488697656 bayes_pls_golite062009
signal transducer activity 0.69727426993974 bayes_pls_golite062009
molecular transducer activity 0.69727426993974 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle