YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: Pfk-PB

General Information:
Name(s) found: Pfk-PB / FBpp0087508 [FlyBase]
Description(s) found:
Found 22 descriptions.
SHOW ALL
  • The gene Phosphofructokinase is referred to in FlyBase by the symbol Dmel\Pfk (CG4001, FBgn0003071). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5997245..6004696. It has the cytological map location 46E8-46F1. There is experimental evidence that it has the molecular function</span>: 6-phosphofructokinase activity. There is experimental evidence that it is involved in the biological process</span>: glycolysis. 10 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 788 amino acids

    Gene Ontology:
    Cellular Component: 6-phosphofructokinase complex [IC][IEA]
    Biological Process: glycolysis [IMP][NAS]
    Molecular Function: 6-phosphofructokinase activity [IMP][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSEINQRFL ARGSQKDKGL AVFTSGGDSQ GMNAAVRACV RMAIYLGCKV YFIREGYQGM  60
   61 VDGGDCIQEA NWASVSSIIH RGGTIIGSAR CQDFRERQGR LKAANNLIQR GITNLVVIGG 120
  121 DGSLTGANLF RQEWSSLLDE LVKNKTITTE QQEKFNVLHI VGLVGSIDND FCGTDMTIGT 180
  181 DTALHRIIEA IDAISSTAYS HQRTFIMEVM GRHCGYLALV GGLACEADFI FIPEMPPKVD 240
  241 WPDRLCSQLA QERSAGQRLN IVIVAEGAMD REGHPITAED VKKVIDERLK HDARITVLGH 300
  301 VQRGGNPSAF DRILACRMGA EATLALMEAT KDSVPVVISL DGNQAVRVPL MECVERTQAV 360
  361 AKAMAEKRWA DAVKLRGRSF ERNLETYKML TRLKPPKENF DADGKGIEGY RLAVMHIGAP 420
  421 ACGMNAAVRS FVRNAIYRGD VVYGINDGVE GLIAGNVREL GWSDVSGWVG QGGAYLGTKR 480
  481 TLPEGKFKEI AARLKEFKIQ GLLIIGGFES YHAAGQIADQ RDNYPQFCIP IVVIPSTISN 540
  541 NVPGTEFSLG CDTGLNEITE ICDRIRQSAQ GTKRRVFVIE TMGGYCGYLA TLAGLAGGAD 600
  601 AAYIYEEKFS IKDLQQDVYH MASKMAEGVS RGLILRNEKA SENYSTDFIY RLYSEEGKGL 660
  661 FTCRMNILGH MQQGGSPTPF DRNMGTKMAA KCVDWLAAQI KANIDANGVV NCKSPDTATL 720
  721 LGIVSRQYRF SPLVDLIAET NFDQRIPKKQ WWLRLRPLLR ILAKHDSAYE EEGMYITVEE 780
  781 ECDTDAVA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..354] PSI-BLAST 105.0 ATP-dependent phosphofructokinase
    2 View Details [355..788] PSI-BLAST 79.0 No description for 2higA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 6-phosphofructokinase activity
    		•  12.7403693686468 bayes_pls_golite062009
  • phosphofructokinase activity
    		•  11.7059647240147 bayes_pls_golite062009
  • fructose-6-phosphate binding
    		•  9.55959144901554 bayes_pls_golite062009
  • fructose binding
    		•  9.55841643584799 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  9.54757838113048 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  3.19280659830412 bayes_pls_golite062009
  • kinase activity
    		•  2.85624705588769 bayes_pls_golite062009
  • fructose-2,6-bisphosphate 2-phosphatase activity
    		•  2.7198911999025 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.67472251964197 bayes_pls_golite062009
  • sugar binding
    		•  2.21212411210899 bayes_pls_golite062009
  • monosaccharide binding
    		•  2.05358532613083 bayes_pls_golite062009
  • transferase activity
    		•  1.97789134877808 bayes_pls_golite062009
  • catalytic activity
    		•  1.89212073381079 bayes_pls_golite062009
  • protein binding
    		•  1.76136621968843 bayes_pls_golite062009
  • binding
    		•  1.57437723650762 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.97067862054315 bayes_pls_golite062009
  • hydrolase activity
    		•  0.276140444059183 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.184982121995695 bayes_pls_golite062009
  • tubulin binding
    		•  0.0889554716245424 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle