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Protein Overview: CG1675-PA

General Information:
Name(s) found: CG1675-PA / FBpp0087463 [FlyBase]
Description(s) found:
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  • gi|7303836|gb|AAF58883.1| CG1675 [Drosophila melanogaster] [NCBI NR]
  • gi|41058129|gb|AAR99114.1| RE34459p [Drosophila melanogaster] [NCBI NR]
  • gi|24652235|ref|NP_610528.1| CG1675 [Drosophila melanogaster] [NCBI NR]
  • Alpha N-terminal protein methyltransferase 1 OS=Drosophila melanogaster GN=Ntmt PE=2 SV=1 [Swiss-Prot]
  • This gene is referred to in FlyBase by the symbol Dmel\CG1675 (CG1675, FBgn0033457). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5753154..5754039. It has the cytological map location 46B4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: methyltransferase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG1675-PA translation from_gene[CG1675 CG1675 FBgn0033457] seq_release:3 mol_weight=30602 cds_boundaries:(2R:4,926,337..4,927,164[+]) aa_length:276 transcript_info:[CG1675-RA seq_release:3] gene_info:[gene symbol:CG1675 FBgn0033457 gene_boundaries:(2R [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V5C9) CG1675 protein [DrosMelano7227.FASTAC.txt]
  • (AE003831) CG1675 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG1675-PA [Drosophila melanogaster]gi|24652235|ref|NP_610528.1| CG1675-PA [Drosophila melanogaster]gi|41058129|gb|AAR99114.1| RE34459p [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:5753209..5754039; ID=FBpp0087463; name=CG1675-PA; parent=FBgn0033457,FBtr0088375; dbxref=GB_protein:AAF58883.1,FlyBase:FBpp0087463,FlyBase_Annotation_IDs:CG1675-PA,REFSEQ:NP_610528,GB_protein:AAF58883; MD5=90078753dddfa5bc5b0bd71bd4ab [fly-100309-contam.fasta]
  • CG1675-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE34459p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:5753209..5754039; ID=FBpp0087463; name=CG1675-PA; parent=FBgn0033457,FBtr0088375; dbxref=GB_protein:AAF58883.1,FlyBase:FBpp0087463,FlyBase_Annotation_IDs:CG1675-PA,REFSEQ:NP_610528,GB_protein:AAF58883; MD5=90078753dddfa5bc5b0bd71bd4ab0c98; length=276; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:5753209..5754039; ID=FBpp0087463; name=CG1675-PA; parent=FBgn0033457,FBtr0088375; dbxref=GB_protein:AAF58883.1,FlyBase:FBpp0087463,FlyBase_Annotation_IDs:CG1675-PA,REFSEQ:NP_610528,GB_protein:AAF58883; MD5=90078753dddfa5bc5b0bd71bd4ab0c98; length=276; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Alpha N-terminal protein methyltransferase 1 OS=Drosophila melanogaster GN=CG1675 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:5753209..5754039; ID=FBpp0087463; name=Ntmt-PA; parent=FBgn0033457,FBtr0088375; dbxref=GB_protein:AAF58883.1,FlyBase:FBpp0087463,FlyBase_Annotation_IDs:CG1675-PA,REFSEQ:NP_610528,GB_protein:AAF58883,FlyMine:FBpp0087463,modMine:FBpp0087463; MD5=90078753dddfa5bc5b0bd71bd4ab0c98; length=276; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:9865704..9866534; ID=FBpp0087463; name=Ntmt-PA; parent=FBgn0033457,FBtr0088375; dbxref=GB_protein:AAF58883.1,FlyBase:FBpp0087463,FlyBase_Annotation_IDs:CG1675-PA,REFSEQ:NP_610528,GB_protein:AAF58883,FlyMine:FBpp0087463,modMine:FBpp0087463; MD5=90078753dddfa5bc5b0bd71bd4ab0c98; length=276; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:9865704..9866534; ID=FBpp0087463; name=Ntmt-PA; parent=FBgn0033457,FBtr0088375; dbxref=GB_protein:AAF58883.1,FlyBase:FBpp0087463,FlyBase_Annotation_IDs:CG1675-PA,REFSEQ:NP_610528,GB_protein:AAF58883,FlyMine:FBpp0087463,modMine:FBpp0087463; MD5=90078753dddfa5bc5b0bd71bd4ab0c98; length=276; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Alpha N-terminal protein methyltransferase 1 OS=Drosophila melanogaster GN=Ntmt PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0087463 type=protein; loc=2R:9865704..9866534; ID=FBpp0087463; name=Ntmt-PA; parent=FBgn0033457,FBtr0088375; dbxref=GB_protein:AAF58883.1,FlyBase:FBpp0087463,FlyBase_Annotation_IDs:CG1675-PA,REFSEQ:NP_610528,GB_protein:AAF58883,FlyMine:FBpp0087463,modMine:FBpp0087463; MD5=90078753dddfa5bc5b0bd71bd4ab0c98; length=276; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:9865704..9866534; ID=FBpp0087463; name=Ntmt-PA; parent=FBgn0033457,FBtr0088375; dbxref=GB_protein:AAF58883.1,FlyBase:FBpp0087463,FlyBase_Annotation_IDs:CG1675-PA,REFSEQ:NP_610528,GB_protein:AAF58883,UniProt/Swiss-Prot:Q6NN40,FlyMine:FBpp0087463,modMine:FBpp0087463; MD5=90078753dddfa5bc5b0bd71bd4ab0c98; length=276; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 276 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: methyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTTLEEQLS DKLQMMDETT DKVQGSSKQK DDSSIAASSD AKTASPSSSD SSTKVAAPES  60
   61 EFYNKAQKYW SEVPATVNGM LGGLGYISAI DIQGSNVFLR EIRVPGNRLA LDCGAGIGRV 120
  121 TRNLLIPRFS CVDLVEQDPA FADKAREYCT SEDGSRGKVG QIYNVGLQKF TPTQQYDLVW 180
  181 TQWVLGHLTD RDLVSFFRRI KQGLAPGAFL CLKENVSSSK KTVEDRNDSS VTRPLDSYEH 240
  241 FLKEAGFRIV RKVKQQNFPK GLFPVYMIAC KPVSKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..276] PSI-BLAST 36.39794 Crystal Structure of Human methyltransferase AD-003 in complex with S-adenosyl-L-homocysteine

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methyltransferase activity
    		•  3.57681394097837 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  3.49392219433935 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.39429041855776 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.07428840534971 bayes_pls_golite062009
  • transferase activity
    		•  2.926540904444 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  2.5924681776558 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  1.76571145896453 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  1.57269280784007 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  0.94499223839747 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  0.794703281700029 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  0.716476158062361 bayes_pls_golite062009
  • DNA binding
    		•  0.71058003448013 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.698509190696763 bayes_pls_golite062009
  • binding
    		•  0.383237930789959 bayes_pls_golite062009
  • rRNA (guanine) methyltransferase activity
    		•  0.0854264678700428 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  0.0408000230099101 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle