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Protein Overview: CG12926-PA

General Information:
Name(s) found: CG12926-PA / FBpp0087586 [FlyBase]
Description(s) found:
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  • gi|7303866|gb|AAF58912.1| CG12926 [Drosophila melanogaster] [NCBI NR]
  • gi|24652156|ref|NP_610510.2| CG12926 [Drosophila melanogaster] [NCBI NR]
  • gi|201065569|gb|ACH92194.1| FI02944p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG12926 (CG12926, FBgn0033437). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5495633..5497792. It has the cytological map location 45F6. Based on sequence similarity, it is predicted to have molecular function</span>: vitamin E binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transport. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG12926-PA translation from_gene[CG12926 CG12926 FBgn0033437] seq_release:3 mol_weight=35494 cds_boundaries:(2R:4,668,984..4,670,041[-]) aa_length:313 transcript_info:[CG12926-RA seq_release:3] gene_info:[gene symbol:CG12926 FBgn0033437 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V5A5) CG12926 protein [DrosMelano7227.FASTAC.txt]
  • (AE003832) CG12926 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG12926-PA [Drosophila melanogaster]gi|24652156|ref|NP_610510.2| CG12926-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(5495854..5496108,5496170..5496542,5496601..5496914); ID=FBpp0087586; name=CG12926-PA; parent=FBgn0033437,FBtr0088502; dbxref=FlyBase:FBpp0087586,FlyBase_Annotation_IDs:CG12926-PA,GB_protein:AAF58912.1,REFSEQ:NP_610510,GB_pr [fly-100309-contam.fasta]
  • CG12926-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(5495854..5496108,5496170..5496542,5496601..5496914); ID=FBpp0087586; name=CG12926-PA; parent=FBgn0033437,FBtr0088502; dbxref=FlyBase:FBpp0087586,FlyBase_Annotation_IDs:CG12926-PA,GB_protein:AAF58912.1,REFSEQ:NP_610510,GB_protein:AAF58912; MD5=b9538c4040a20d2ffe9c4e1586c72d7b; length=313; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(5495854..5496108,5496170..5496542,5496601..5496914); ID=FBpp0087586; name=CG12926-PA; parent=FBgn0033437,FBtr0088502; dbxref=FlyBase:FBpp0087586,FlyBase_Annotation_IDs:CG12926-PA,GB_protein:AAF58912.1,REFSEQ:NP_610510,GB_protein:AAF58912; MD5=b9538c4040a20d2ffe9c4e1586c72d7b; length=313; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG12926 OS=Drosophila melanogaster GN=CG12926 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(5495854..5496108,5496170..5496542,5496601..5496914); ID=FBpp0087586; name=CG12926-PA; parent=FBgn0033437,FBtr0088502; dbxref=FlyBase:FBpp0087586,FlyBase_Annotation_IDs:CG12926-PA,GB_protein:AAF58912.1,REFSEQ:NP_610510,GB_protein:AAF58912,FlyMine:FBpp0087586,modMine:FBpp0087586; MD5=b9538c4040a20d2ffe9c4e1586c72d7b; length=313; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(9609096..9609409,9608665..9609037,9608349..9608603)); ID=FBpp0087586; name=CG12926-PA; parent=FBgn0033437,FBtr0088502; dbxref=FlyBase:FBpp0087586,FlyBase_Annotation_IDs:CG12926-PA,GB_protein:AAF58912.1,REFSEQ:NP_610510,GB_protein:AAF58912,FlyMine:FBpp0087586,modMine:FBpp0087586; MD5=b9538c4040a20d2ffe9c4e1586c72d7b; length=313; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(9609096..9609409,9608665..9609037,9608349..9608603)); ID=FBpp0087586; name=CG12926-PA; parent=FBgn0033437,FBtr0088502; dbxref=FlyBase:FBpp0087586,FlyBase_Annotation_IDs:CG12926-PA,GB_protein:AAF58912.1,REFSEQ:NP_610510,GB_protein:AAF58912,FlyMine:FBpp0087586,modMine:FBpp0087586; MD5=b9538c4040a20d2ffe9c4e1586c72d7b; length=313; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0087586 type=protein; loc=2R:complement(join(9609096..9609409,9608665..9609037,9608349..9608603)); ID=FBpp0087586; name=CG12926-PA; parent=FBgn0033437,FBtr0088502; dbxref=FlyBase:FBpp0087586,FlyBase_Annotation_IDs:CG12926-PA,GB_protein:AAF58912.1,REFSEQ:NP_610510,GB_protein:AAF58912,FlyMine:FBpp0087586,modMine:FBpp0087586; MD5=b9538c4040a20d2ffe9c4e1586c72d7b; length=313; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(9609096..9609409,9608665..9609037,9608349..9608603)); ID=FBpp0087586; name=CG12926-PA; parent=FBgn0033437,FBtr0088502; dbxref=FlyBase:FBpp0087586,FlyBase_Annotation_IDs:CG12926-PA,GB_protein:AAF58912.1,REFSEQ:NP_610510,GB_protein:AAF58912,UniProt/TrEMBL:A1Z7X8,FlyMine:FBpp0087586,modMine:FBpp0087586; MD5=b9538c4040a20d2ffe9c4e1586c72d7b; length=313; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 313 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: transport [IEA]
    Molecular Function: vitamin E binding [ISS]
    transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEAYSNSIR SLSPELAKKA HDELGEIPDR IDEDIETLRT WISKQPHLKA RQDAQFLVAF  60
   61 LRGCKYSLEK TKLKLDNFYA MRGAVPELYK NRIVGEKQLS ILDTGCLLRL PQPLQADGPR 120
  121 IHISRYGQYD SKKYSIAEVV QVNTMLGEIQ IREDDNAMIS GFVEIIDMKG VGAGHLFQFD 180
  181 AVLVKKLAVL GDKAYPYRPK GFHFVNAPSS AEKFMSIAKS LMSEKIRKRF HIHSKLDSLY 240
  241 KYVPKECLPA EYGGSNGTIQ DVVSTWRTKL LAYKPFFEEE ASYGTNEKLR RGQPVSAESL 300
  301 FGIEGSFRKL DID

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..313] PSI-BLAST 49.39794 The Molecular Basis of Vitamin E Retention: Structure of Human Alpha-Tocopherol Transfer Protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • vitamin E binding
    		•  3.58949389323234 bayes_pls_golite062009
  • binding
    		•  1.48494259967762 bayes_pls_golite062009
  • vitamin binding
    		•  1.00539404172882 bayes_pls_golite062009
  • phosphatidylinositol transporter activity
    		•  0.754580529725379 bayes_pls_golite062009
  • retinal binding
    		•  0.646905718502968 bayes_pls_golite062009
  • phospholipid transporter activity
    		•  0.48474525678945 bayes_pls_golite062009
  • protein binding
    		•  0.408110742195811 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle