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Protein Overview: Pmm45A-PA

General Information:
Name(s) found: Pmm45A-PA / FBpp0087711 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Phosphomannomutase 45A is referred to in FlyBase by the symbol Dmel\Pmm45A (CG8073, FBgn0033377). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4994647..4997228. It has the cytological map location 45A6-45A7. Based on sequence similarity, it is predicted to have molecular function</span>: phosphomannomutase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate metabolic process. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 623 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: carbohydrate metabolic process [IEA]
    Molecular Function: magnesium ion binding [IEA]
    phosphomannomutase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCQSGGQMLC EIKNMALSGD PELDGEIRKW IRWDKCASTA CQIMDAVRAK DWDTLRKRLC  60
   61 TRISFGTAGL RACMRAGFDS MNELVVIQTA QGLCEYIKEQ YPDPADWSGR GIVFGYDGRY 120
  121 NSHRFAELSA IVFLNNDFKV WLFKRYVATP MVPFAILRLQ CLAGVMVTAS HNPKEDNGYK 180
  181 VYWTNGAQII PPHDEGIQES ILNNLEPKGS SWDDSAMCSN TMLEDPYDIV VPPYFDILKK 240
  241 QLPCTSLEAN GRCSLSFTYT AMHGVGYAFV KQAFARINLK PFISVCEQQE PDPEFPTTPM 300
  301 PNPEEGKTSL DLSIKTAKAN SSQIILANDP DADRLAVAEV REDGSYKLFS GNEVGALLGW 360
  361 WSLELHKMRE PDCDVSNCVM IASTVSSKIL RAMAEREGFQ FFETLTGFKW MGNKAIELQQ 420
  421 AGKTVLFAFE EAIGFMVGTT VLDKDGVSAA GHLATMACYL RCKLCMTLQE KLRDIYETYG 480
  481 FHTTVSSYVI CRCPPVIEQI FERLRTWDEG KADTYPTSIL NGEYEIENVR DLTTGFDSST 540
  541 GDKKATLPTS SSSQMITFTF KNGLVVTLRT SGTEPKMKYY AEMCGKPDEK NWAKLTNTMN 600
  601 TMVEAIVEEF YEPSKNGLQR RKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..623] PSI-BLAST 118.0 Phosphoglucomutase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • intramolecular transferase activity, phosphotransferases
    		•  2.81013216982616 bayes_pls_golite062009
  • phosphoglucomutase activity
    		•  2.69310705391365 bayes_pls_golite062009
  • isomerase activity
    		•  2.10512181960585 bayes_pls_golite062009
  • catalytic activity
    		•  1.90838528948382 bayes_pls_golite062009
  • binding
    		•  1.61980820714401 bayes_pls_golite062009
  • intramolecular transferase activity
    		•  1.30184724715376 bayes_pls_golite062009
  • phosphomannomutase activity
    		•  0.96914970670646 bayes_pls_golite062009
  • protein binding
    		•  0.259532204752794 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle