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Protein Overview: CG8777-PA

General Information:
Name(s) found: CG8777-PA / FBpp0087646 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8777 (CG8777, FBgn0033376). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4986075..4990661. It has the cytological map location 45A3-45A4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: nuclear-transcribed mRNA catabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1233 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nuclear-transcribed mRNA catabolic process [IMP]
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAVKESKAL IKDIRETIKL GKHAEAIPKC QRLLKSEPEN AMGYLLLGAA YQNIDKAEAA  60
   61 KNLRQCIKCT DGPAPAALLG LANCAPSNEL PEIYDQLADL QPEQSLNYWE KLFNLASDSN 120
  121 VAPFCFTVLK KRVQDTENGN FTKIQEYLGR IWVSNDFEIA PEDTQLYKTT MEALLQNSEP 180
  181 SARSVVYKRY LKWLYKKQDY ETCVRHACNM TESHPKDVYG FEWICKTYCE HHEQSEIVSW 240
  241 QQELRHPIQV YAEQLLELNP NSNLALLVKA LDLFAEGQVV ASRQLALQAQ KSQPAYKVTL 300
  301 ELLARIHMEL GAYKLALQLW QEIGQENDAY ALCLSHEKGV SKLREAVTIL QTLENSEGNI 360
  361 KSLARCYFKL GELHLLKDLP LDDLTKAEFV LSPSEALQEI ADCKTFEAYL LCGKLHMALK 420
  421 NYSDALNYVL KATRLRPHFA ECFDYLGKLY PLATGDFSRA RKCYEKCISL NPLAEEAVDA 480
  481 LSFIYQEQGE EELNETLLLN TLSHLGSNES IRLQYKLGLH FSHVKKWDSA IQCFRIAIKN 540
  541 DSRCISYWES LGDAYAGRGS YNSAIRVFQK ILELSPENNY ALLQIASVKT TIRMYTESIE 600
  601 DYDTLLQRNP TYLPGLRGAA EAHIGIANSL KSQNLYGRSK AHFQLALEHL QSAFLQREAQ 660
  661 GMVWLWRLSA NIFVQTAQLP HSLANLDVAG NLAKREEPIA YLSRKDLLQL AQRFYLCALK 720
  721 LKQNTYLWYE LSLASYYSAI LIPEDANGHL ETATKACKMA IKECSNRWQN WNLLGVINMN 780
  781 SENENLPLAQ HCFIQAVVLE KKCYTAWTNL GVLYIKLNEV RLANEAFTRA QQSSPVYANA 840
  841 WIGQAMVAEL IGDREEAFDL FRHCQQFDYH PEAALGFAHW VCEMLSTPGS FDKPRIKHAI 900
  901 EHMYADVLAL DAINWYVQNE ETDATPASLS FQGFLYARKN LYRQAIEAFT RACKLCEPGA 960
  961 DRDKLYTNLG YLYLKIDQPE QAAHALNTVA HATFKPIIGL AQAYYLAGQL QESYSIYNSV1020
 1021 LGNVVDHGDD KAATILVAMA SMIYDFQGEA DTKTLLYQCV LLKEVPIQAL FSALALGILH1080
 1081 RDNALIHTIL TELNAYAFKK EYCADISYLT AHYILINEGA RRALCYLQTR IRMFPNSRSL1140
 1141 RSVVLKFLLD YFSDDQSYRL ATSNMGRITL TLGHTKQQNS ILASEEALTT IYASQAVSAV1200
 1201 DKTCSMKLLQ RAILLSPTDQ RARQLLSAII ANS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..488] PSI-BLAST 29.69897 No description for 2gw1A was found.
    2 View Details [489..692] PSI-BLAST 47.69897 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
    3 View Details [693..922] PSI-BLAST 11.69897 FKBP51, C-terminal domain; FKBP51, N-terminal domains
    4 View Details [923..1046] FFAS03 4.97 No description for 2dbaA was found.
    5 View Details [1047..1233] PSI-BLAST 3.39794 Protein farnesyltransferase alpha-subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.787280988128024 bayes_pls_golite062009
  • protein binding
    		•  0.212989569759479 bayes_pls_golite062009
  • hydrolase activity
    		•  0.142615944899055 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle