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Protein Overview: Dbp45A-PA

General Information:
Name(s) found: Dbp45A-PA / FBpp0087645 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene DEAD box protein 45A is referred to in FlyBase by the symbol Dmel\Dbp45A (CG12759, FBgn0010220). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4975358..4977304. It has the cytological map location 45A1-45A2. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent RNA helicase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of alternative nuclear mRNA splicing, via spliceosome. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 521 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC]
    Biological Process: regulation of alternative nuclear mRNA splicing, via spliceosome [IMP]
    Molecular Function: nucleic acid binding [IEA]
    ATP binding [IEA]
    ATP-dependent RNA helicase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRKEANPFQ ILGLRPWLVK QLTKLGLKGA TPIQQKCIPA ILAGQDCIGA AKTGSGKTFA  60
   61 FALPILERLS EEPVSHFALV LTPTHELAYQ ISEQFLVAGQ AMGVRVCVVS GGTDQMVESQ 120
  121 KLMQRPHIVV AMPGRLADHL TGCDTFSFDN LKYLVVDEAD RMLNGDFDES LSIIERCLPK 180
  181 TRQNLFFSAT MKDFIKESSI FPIASDCFEW SQDSDVATVE TLDQRYLLCA DYDRDMVLIE 240
  241 ALRKYREENE NANVMIFTNT KKYCQLLSMT LKNMEIDNVC LHGFMRQKER VAALSRFKSN 300
  301 QIRTLIATDV AARGLDIPSV ELVMNHMLPR TPKEYIHRVG RTARAGRKGM SISIFRFPRD 360
  361 LELLAAIEEE INTKLTEHPI DQRMVERIFM QVNVTRRESE MQLDNNDFDE RAQNYRRKTW 420
  421 IMEGKDPDQM EALYRKKQKD KLREIRRKRK LQHAEPAASE EGKALLQDER FKSVDSARFE 480
  481 KKGKGRSRAT QEDTPTKPLK RLNKEKPVAQ KGRADVKKDK A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..375] PSI-BLAST 88.30103 No description for 2hxyA was found.
    2 View Details [376..521] PSI-BLAST 20.522879 Nucleotide excision repair enzyme UvrB


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle