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Protein Overview: CG8232-PA

General Information:
Name(s) found: CG8232-PA / FBpp0087735 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8232 (CG8232, FBgn0033352). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4815679..4820608. It has the cytological map location 44F8-44F9. Based on sequence similarity, it is predicted to have molecular function</span>: poly(A)-specific ribonuclease activity. There is experimental evidence that it is involved in the biological process</span>: nuclear-transcribed mRNA poly(A) tail shortening. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1241 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: nuclear-transcribed mRNA poly(A) tail shortening [IGI]
    ubiquitin-dependent protein catabolic process [IEA]
    Molecular Function: poly(A)-specific ribonuclease activity [ISS]
    nucleic acid binding [IEA]
    ubiquitin thiolesterase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYVYCGTDP IGASEDILSV YDAGSAPGNG HFSPSFNGFN IGTTDPEYVE LVPVLADGGE  60
   61 HFGVSSVAFD DYEELLWMGN QGGHVTSYYT NSMQKYTSFQ VHATDIVRDI STLDSGVLAL 120
  121 TQTSLRHQIR RGLPKFTFKS NNMKEMVSML QLSPHRLVMA GLQDELIDFD LRTLKETRIE 180
  181 HVGAGGCTVL RKNSRYLFAG DQLGTVTLRD LNSLSVQHTI KTHTNILSDF SVQGNLLISC 240
  241 GYSGRQNNLA IDRFLMVYDL RMLRLIAPIQ VMIDPQMLKF LPSLTSQLAV VSSYGQVQLV 300
  301 DTVELSEPRV SMYQINTNGS QCLSFDISSS SQAMAFGDQS GHINMIAAVQ TPQPQFNLYS 360
  361 RSTEFADVVP QLPMVSITDT NFPLSSVMLP HLTTGTQWFS DWPEELLRYR YHRPKTIDPE 420
  421 VLSNMKMQGP IGYSPNPRTA RRNQIPYVIE QGGVCSPNGN GTAAATKAEN GVKIIPRRYR 480
  481 KVELKYTKLG TQDFDFDQHN QTCFAGLEAT LPNSYCNAML QILYFTDALR VKLLEHSCIK 540
  541 EFCLSCELGF LFNMLDKSTA SSPCQASNFL RSFRTVPEAS ALGLILTDRS SNVNLISLIQ 600
  601 NWNRFILHQM HYEIFDSSKN ASTYSGSVQT STNAENAGSS ETSGSSDLYD SISDENSKED 660
  661 DRERSKINAE TDISKIFGTK QICINRCIKC QEEKIKESIL LACNLSYPNH IKDSDQYFNF 720
  721 GTILKRSLSS EKSIQAFCER CKKFSPTNQS VKVTSLPQIL SINCGLNNEK DITFLKRQLN 780
  781 RCSEKTTVDA AASLSTSKPC RYGANCSRSD CHFMHPDRKS PSHTSQPNAV NNSPNGRQKS 840
  841 WFPLTFTMGI NDQGEVQVQT QSDASSGKSE QEEETEKPPT KGLDNNRMYA LHAVVCQVDD 900
  901 GTQKNLVSLI NVQRPYHTMK LAESADDPQS QWYIFNDFSI SPVSPQESVW FTLDWKVPCI 960
  961 LFYRHVEDDS ESASTTSSTV TESEETIPSE SSSGSPTNLS NPFLEEIVSP MLGNLSADAT1020
 1021 LQPLQSDEMP QSGDLVAMDA EFVTLNPEEN EIRPDGKTAT IKPCHMSVAR ISCIRGQGPA1080
 1081 EGVPFMDDYI STQEKVVDYL TQFSGIKPGD LDANFSKKRL TALKYSYQKL KYLVDVGVIF1140
 1141 VGHGLKNDFR VINIYVPSEQ IIDTVHLFHM PHHRMVSLRF LAWHFLGTKI QSETHDSIED1200
 1201 ARTTLQLYKH YLKLQEEKKF ANALKNLYER GKQLQWKVPE D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..142] PSI-BLAST 65.522879 No description for 2ovpB was found.
    2 View Details [143..539] PSI-BLAST 5.39794 Crystal structure of HIV-1 Tat derived nonapeptides Tat(1-9) bound to the active site of Dipeptidyl peptidase IV (CD26)
    3 View Details [540..868] PSI-BLAST 50.69897 No description for 2hd5A was found.
    4 View Details [869..1026] FFAS03 3.98 Crystal structure of HAUSP
    5 View Details [1027..1241] PSI-BLAST 41.0 human ISG20


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle