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Protein Overview: Pbp49-PA, Pbp49-PB

General Information:
Name(s) found: Pbp49-PB / FBpp0289883 [FlyBase]
Pbp49-PA / FBpp0289882 [FlyBase]
Description(s) found:
Found 33 descriptions.
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  • The gene PSEA-binding protein 49kD is referred to in FlyBase by the symbol Dmel\Pbp49 (CG42515, FBgn0260398). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4016859..4018837. It has the cytological map location 44B3. There is experimental evidence that it has the molecular function</span>: bent DNA binding; protein binding; sequence-specific DNA binding; DNA binding. There is experimental evidence that it is involved in the biological process</span>: snRNA transcription from RNA polymerase III promoter; snRNA transcription from RNA polymerase II promoter; protein-DNA complex assembly. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene PSEA-binding protein 49kD is referred to in FlyBase by the symbol Dmel\Pbp49 (CG42515, FBgn0260398). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4016859..4018837. It has the cytological map location 44B3. There is experimental evidence that it has the molecular function</span>: bent DNA binding; protein binding; sequence-specific DNA binding; DNA binding. There is experimental evidence that it is involved in the biological process</span>: snRNA transcription from RNA polymerase III promoter; snRNA transcription from RNA polymerase II promoter; protein-DNA complex assembly. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 377 amino acids

    Gene Ontology:
    Cellular Component: snRNA-activating protein complex [IDA][IPI][ISS]
    Biological Process: protein-DNA complex assembly [IDA]
    snRNA transcription from RNA polymerase II promoter [IDA]
    snRNA transcription from RNA polymerase III promoter [IDA]
    Molecular Function: DNA binding [IDA]
    protein binding [IPI]
    sequence-specific DNA binding [IDA]
    bent DNA binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTTYITTNP ALSLRDFLAD YQKKISGTAD EVPFFLQKNP VLVDVSESCS LDLIESPDDS  60
   61 SIAVFQPAAD KCRPTFSPPQ ENQHVPSTFT ALSQHKDKSR KCPFGRTQYS HKLNPTPTDS 120
  121 PNLHIDACGE LELTVRLYRP PRAYHRGFKV EIPVFAEEFV CLGSNYLTEL RDKISCVCNG 180
  181 KRFVDISDDP DAPLPSIDTN PGYFFINDTF YNDQRNPDNP DYSKTVLQWA ARANGVNGET 240
  241 LKVESMEGKR FIDLTVSPGS PLHYLHHGNC EHLFVISQVE VLTPLSKRPD RSLYPYPHAF 300
  301 STFNRRTCYM CGIRSYSFIV NQSRRQLHDP SYLCRRCFLS FFYVDGVKLG QFKAYRMYDH 360
  361 VELEGEEEDI KQQNLPS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..199] MSA 3.032963 View MSA. No confident structure predictions are available.
    2 View Details [200..294] deduced N/A No confident structure predictions are available.
    3 View Details [295..377] MSA 2.033981 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle