Protein Overview: Socs44A-PA

General Information:
Name(s) found:	Socs44A-PA / FBpp0087862 [FlyBase]
Description(s) found: Found 24 descriptions. SHOW ALL	The gene Suppressor of Cytokine Signaling at 44A is referred to in FlyBase by the symbol Dmel\Socs44A (CG2160, FBgn0033266). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4015136..4016981. It has the cytological map location 44B3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of epidermal growth factor receptor signaling pathway; negative regulation of JAK-STAT cascade. 4 alleles are reported. The phenotype of these alleles is annotated with: wing vein L3. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	342 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	positive regulation of epidermal growth factor receptor signaling pathway [IGI] negative regulation of JAK-STAT cascade [IGI]
Molecular Function:	protein binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHGDQSQNQ SSQRSQALTG GGDSPRDREK EKKGWFHSLT RRKKSDSALA VTASAAVSTS  60
   61 GSQNNNNEVC VLEAADSSMA SCSNGGTGTG TLRRRRDKDK RNVFARLRRK VGQGLSSLRN 120
  121 WHSMGDCDDG GTTDATYEFL TPAICPEPTL PFTHDYLRFI RKKWLEREDA HSPNQIMYKA 180
  181 CSEMLNQVWY WGEISRRDSQ RQLSDKPTGS FLVRDSETSG SQFTLSFRIV NVTLHYRLEY 240
  241 RDNFWHFEEL KYESIVEMIE DILHRCTNDN FVCFVKVPNE MQPPFPVILK YPLSRYSNMP 300
  301 KLQDLCRRVL QRQMSREQLA QLPVPAQMLE YLSVERELVF QS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
protein binding	3.19631993182765	bayes_pls_golite062009
binding	2.48735671726158	bayes_pls_golite062009
insulin receptor binding	2.1238568876176	bayes_pls_golite062009
molecular adaptor activity	1.33740973673697	bayes_pls_golite062009
SH3/SH2 adaptor activity	1.2323381312171	bayes_pls_golite062009
growth hormone receptor binding	1.17624762106986	bayes_pls_golite062009
signal transducer activity	0.999269271132931	bayes_pls_golite062009
molecular transducer activity	0.999269271132931	bayes_pls_golite062009
insulin-like growth factor receptor binding	0.950445630788802	bayes_pls_golite062009
protein binding, bridging	0.83823250804321	bayes_pls_golite062009
receptor binding	0.460399756639525	bayes_pls_golite062009
cytoskeletal protein binding	0.116213194167522	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..342]	PSI-BLAST	59.0	No description for 2h8hA was found.

Protein Overview: Socs44A-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: