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Protein Overview: FBpp0307863, kap...

General Information:
Name(s) found: FBpp0307863 [FlyBase]
kappaB-Ras-PB / FBpp0289079 [FlyBase]
kappaB-Ras-PA / FBpp0088074 [FlyBase]
Description(s) found:
Found 40 descriptions.
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  • type=protein; loc=2R:complement(3332531..3333022,3333087..3333200); ID=FBpp0307863; name=kappaB-Ras-PC; parent=FBgn0040513,FBtr0336926; dbxref=REFSEQ:NP_001260770,GB_protein:AGB93303,FlyBase:FBpp0307863,FlyBase_Annotation_IDs:CG1669-PC; MD5=38f4c0598dfbf4ed2e340a8d5f9a68c0; length=201; release=r5.56; species=Dmel; [FlyBase]
  • The gene Ã?&#142;Ã?ºB-Ras is referred to in FlyBase by the symbol Dmel\Ã?&#142;Ã?ºB-Ras (CG1669, FBgn0040513). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3331325..3333266. It has the cytological map location 43C1. There is experimental evidence that it has the molecular function</span>: protein binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of I-kappaB kinase/NF-kappaB cascade. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Ã?&#142;Ã?ºB-Ras is referred to in FlyBase by the symbol Dmel\Ã?&#142;Ã?ºB-Ras (CG1669, FBgn0040513). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3331325..3333266. It has the cytological map location 43C1. There is experimental evidence that it has the molecular function</span>: protein binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of I-kappaB kinase/NF-kappaB cascade. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 201 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of I-kappaB kinase/NF-kappaB cascade [ISS]
    Molecular Function: GTP binding [IEA][ISS]
    protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNAKIGKVG KVLVCGMKGV GKTALIEQLV YGHVNPETEL HPTIEDIYVA SVDTGRGGAR  60
   61 ETLRIYDTAG LQGEQQQLPR HYLQFPDAFV LVYDPMDPRS LDMLADIKAD IEKHKEKKEI 120
  121 PVVVLANVRA RAAPNPVEKV MDRANIWCQR ERIKHYTVNA MERPSLYEPF TTLCARLHPM 180
  181 QTKSTFPQLR QVMQNRQKSE A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..201] PSI-BLAST 44.69897 Structure of RabGDP-dissociation inhibitor in complex with prenylated YPT1 GTPase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.7440092435568 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.1290341608517 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.12882056931709 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.12279673986875 bayes_pls_golite062009
  • nucleotide binding
    		•  1.10746768649988 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.388587892299301 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.372638007722845 bayes_pls_golite062009
  • GTP binding
    		•  0.364508542344128 bayes_pls_golite062009
  • ATP binding
    		•  0.103046188112829 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.0844273923195277 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.0631983477225431 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle