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Protein Overview: Gadd45-PA

General Information:
Name(s) found: Gadd45-PA / FBpp0088120 [FlyBase]
Description(s) found:
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  • gi|7304244|gb|AAF59278.1| Gadd45 [Drosophila melanogaster] [NCBI NR]
  • gi|242118024|gb|ACS78061.1| FI09246p [Drosophila melanogaster] [NCBI NR]
  • gi|20129739|ref|NP_610264.1| Gadd45 [Drosophila melanogaster] [NCBI NR]
  • The gene Gadd45 is referred to in FlyBase by the symbol Dmel\Gadd45 (CG11086, FBgn0033153). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3136668..3138160. It has the cytological map location 43A2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: JNK cascade. 3 alleles are reported. The phenotypes of these alleles are annotated with: chorion; follicle cell; egg chamber; dorsal appendage; nurse cell. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG11086-PA translation from_gene[CG11086 CG11086 FBgn0033153] seq_release:3 mol_weight=18097 cds_boundaries:(2R:2,310,323..2,310,811[+]) aa_length:163 transcript_info:[CG11086-RA seq_release:3] gene_info:[gene symbol:CG11086 FBgn0033153 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V4J2) CG11086 protein [DrosMelano7227.FASTAC.txt]
  • (AE003842) CG11086 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG11086-PA [Drosophila melanogaster]gi|20129739|ref|NP_610264.1| CG11086-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:3136926..3137417; ID=FBpp0088120; name=Gadd45-PA; parent=FBgn0033153,FBtr0089049; dbxref=FlyBase:FBpp0088120,FlyBase_Annotation_IDs:CG11086-PA,GB_protein:AAF59278.1,REFSEQ:NP_610264,GB_protein:AAF59278; MD5=80de190acc4f22b96eb100cf1bd [fly-100309-contam.fasta]
  • CG11086-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Gadd45 CG11086-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:3136926..3137417; ID=FBpp0088120; name=Gadd45-PA; parent=FBgn0033153,FBtr0089049; dbxref=FlyBase:FBpp0088120,FlyBase_Annotation_IDs:CG11086-PA,GB_protein:AAF59278.1,REFSEQ:NP_610264,GB_protein:AAF59278; MD5=80de190acc4f22b96eb100cf1bde2bc7; length=163; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:3136926..3137417; ID=FBpp0088120; name=Gadd45-PA; parent=FBgn0033153,FBtr0089049; dbxref=FlyBase:FBpp0088120,FlyBase_Annotation_IDs:CG11086-PA,GB_protein:AAF59278.1,REFSEQ:NP_610264,GB_protein:AAF59278; MD5=80de190acc4f22b96eb100cf1bde2bc7; length=163; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • FI09246p OS=Drosophila melanogaster GN=Gadd45 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:3136926..3137417; ID=FBpp0088120; name=Gadd45-PA; parent=FBgn0033153,FBtr0089049; dbxref=FlyBase:FBpp0088120,FlyBase_Annotation_IDs:CG11086-PA,GB_protein:AAF59278.1,REFSEQ:NP_610264,GB_protein:AAF59278,FlyMine:FBpp0088120,modMine:FBpp0088120; MD5=80de190acc4f22b96eb100cf1bde2bc7; length=163; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:7249421..7249912; ID=FBpp0088120; name=Gadd45-PA; parent=FBgn0033153,FBtr0089049; dbxref=FlyBase:FBpp0088120,FlyBase_Annotation_IDs:CG11086-PA,GB_protein:AAF59278.1,REFSEQ:NP_610264,GB_protein:AAF59278,FlyMine:FBpp0088120,modMine:FBpp0088120; MD5=80de190acc4f22b96eb100cf1bde2bc7; length=163; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:7249421..7249912; ID=FBpp0088120; name=Gadd45-PA; parent=FBgn0033153,FBtr0089049; dbxref=FlyBase:FBpp0088120,FlyBase_Annotation_IDs:CG11086-PA,GB_protein:AAF59278.1,REFSEQ:NP_610264,GB_protein:AAF59278,FlyMine:FBpp0088120,modMine:FBpp0088120; MD5=80de190acc4f22b96eb100cf1bde2bc7; length=163; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0088120 type=protein; loc=2R:7249421..7249912; ID=FBpp0088120; name=Gadd45-PA; parent=FBgn0033153,FBtr0089049; dbxref=FlyBase:FBpp0088120,FlyBase_Annotation_IDs:CG11086-PA,GB_protein:AAF59278.1,REFSEQ:NP_610264,GB_protein:AAF59278,FlyMine:FBpp0088120,modMine:FBpp0088120; MD5=80de190acc4f22b96eb100cf1bde2bc7; length=163; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:7249421..7249912; ID=FBpp0088120; name=Gadd45-PA; parent=FBgn0033153,FBtr0089049; dbxref=FlyBase:FBpp0088120,FlyBase_Annotation_IDs:CG11086-PA,GB_protein:AAF59278.1,REFSEQ:NP_610264,GB_protein:AAF59278,UniProt/TrEMBL:A1Z6W5,FlyMine:FBpp0088120,modMine:FBpp0088120; MD5=80de190acc4f22b96eb100cf1bde2bc7; length=163; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 163 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: JNK cascade [IGI]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVEENCSMH HLERELDLEL EIDMAMECAP IGRTIKSALL RAQSEARVIV GLSAAINVLS  60
   61 KSPEGSLFCL MAQPKDGDSA THMHEVLLEA FCYENDIYVI KVDDATKLSR ILGQDSVESC 120
  121 CLVQKVWADA PEEQLTKAEN QLVDYCEAHW DAPQQPIVQL PAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..163] PSI-BLAST 10.0 Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.34187530323842 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.75603194702351 bayes_pls_golite062009
  • protein binding
    		•  0.381324299701367 bayes_pls_golite062009
  • RNA binding
    		•  0.359317669023596 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle