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Protein Overview: CG8677-PA

General Information:
Name(s) found: CG8677-PA / FBpp0081006 [FlyBase]
Description(s) found:
Found 11 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8677 (CG8677, FBgn0026577). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:21221336..21234035. It has the cytological map location 39B3-39B4. Based on sequence similarity, it is predicted to have molecular function</span>: transcription repressor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription, DNA-dependent. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2759 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: negative regulation of transcription, DNA-dependent [ISS]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IEA]
    transcription repressor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASSAAAAA PTNPIPLPTD SISEECKDDD ALTSTLHTCA NDPDFAVICA FLQKFGKDLG  60
   61 LNLPNFKHLQ EWLTNNNDVP ELRDLHIKLL RKTRKTVHEK SWESALSKFC FGYSVQDAWE 120
  121 IERFGYRNSS LKVKLRIFRE LLESQFERNA KFRAHILTLN ADTLRSEPIG RDRLGHAYWL 180
  181 TQDAHCNLRI YQEHLDEEIW QVVATNRDEF VNLISRLRGN EVVLPSKDIG EADEDTSSSN 240
  241 SCHPKPPPPE QKEEEDDEEV GDEPEKTVPN LKIKLRSPEQ EDQKSKKVKP LLISQAKLSS 300
  301 SASPAPTKKR SIEDVDSSPT ASQEEQQKKH RPTLLDTKRI KKPSRYESTK DEIEEESGEE 360
  361 DEEEEDEEDS ELDEGEEEED VDSAAADIEE DDDEEDTGEP IEDPTIVVQG QGSGLDCEAI 420
  421 PYNLIGNFDY EDDLEIGEAI ADPMLHVIGQ GWGTDCLVGN GKNEASVEET STRTSEPKAT 480
  481 FFFGEPGCLK LSPMKQTSKP EAKRGIFDSL SEEKTNGESE KCIVNTPPRN GSELTKTLGD 540
  541 SEETASASAA TLEETNICQE ANVNKISDDQ IKKKESVPVA KRNIQDSTIS VIEKNEEISK 600
  601 GRTESEAIEE GVRNRTEVSV LQNNSNESDN SSIQTQDQHK VPADLNNTKK PVTEKCVLES 660
  661 GTVEDKLVIN HQQISTNALD TACDEKLSCE TESPVPNQHD SKMKSEQETA TSAKESVSES 720
  721 SPTDGEDETA KSKCLIDPYA GKTNDKGIII NKIDKAEGVI KTLLQDDPPK DISKSETNTT 780
  781 CLEINISPSA EHRISEKVQT IEPSTSQNLL FEDNGKSGEV DGKSRTSGAV EEISKTSTLL 840
  841 NRKRRLNDSQ SALRNSTSES EVHEEEPQDD DPTLDDLDVG GKRIKMRPKT TNAESRRKVE 900
  901 AQKTQIEETT SSSGEDDARI RRKCIAPHTK TKPTLEEIIE RKLKKSIEMD LPEKTTEKVM 960
  961 EMPTQLMQKT REATPPIISL SPQKKTPITK PLKKNLLTQL RQEESEEETI PRKRTNSETL1020
 1021 VPAIPASNVL CQPDERHRKR RSSEDANEAF SKESSPTEVP PSAVSEKLKR NNEQDIQEEV1080
 1081 EDPLAMSVKD SLRSAKDQSP VPEGSARRSG RRGGPAVIHS ELPQPKRTRG GARDKMQPEV1140
 1141 NAELKQESED DEKISTKIKS EAKDDPAPES PENRKKPEEK PIKEEPNEEP KPKVGRGRGP1200
 1201 RKKREVDTTN IIETNDSETP VRQSRRIAQQ KIKEEAERRK QEEVALRTMK QELKKKKKAE1260
 1261 KEADPTVLEP SGEESESEAS EAEEEARNKK KKKCPGKDGW SSDSEEQPES EEEEEEPPHY1320
 1321 ETDPGSPLFR SDHEFSPESE LEDESQVVPM KRARTVRKEN ADDLEEEDAE EACQKCGKSD1380
 1381 HPEWILLCDT PTCNKGYHCS CLSPVLFYIP EGDWHCPPCQ QEQLIAALER QLEQYDTLVA1440
 1441 QKQQERILAE EQAERERQEL EAATLAAKDE NFKSEKEEDE DDRDDMAVGK AEKVKRRRGD1500
 1501 GRINRRAAKR GTRRRRGNES DSSHRKSLGS GSRSGSGSDS SSDNSTSFSD SDDEPIYKLR1560
 1561 KRRQINVSYR LNEYDDLINS ALKKEMDEVA GAGNLGRGKD ISTIIEADKE KARRDDLPTE1620
 1621 DEVGNKEDGE KDKQKSKSSG SSPSSSEDEV PLKRSNKFKQ PPAKKKARKL TTLDVSSEED1680
 1681 HGSDEDFKTS SYSDEDTSQS ASGDSDSSLE AYRRPGRGKK QRKAARRAAR ERRKDRKFVV1740
 1741 EESDESEDED QKRRTTKSKK KKDDSDYTET ETEDDDDNEL SDNVDSADLC DDTTSESEDG1800
 1801 AWNPSSKKKK TVAAKKSNSS GGIARKSPKL KKLATQAEKK VKRLEYSDDD ISESDLEEDD1860
 1861 DDDEEDEEGV PLSGKGSGKQ PRSQPLKPTA SSTLTGKGKG KGKAKKKKQV SSEEEDGAAS1920
 1921 DDRTRTRGRR YAYIEDDDDS SDGGIKPGVH RPDTPPEERQ KFIQRQEEIK RMLAEKNAEG1980
 1981 AKIAATPRLT PLKSGVTASE KRTPGKAASG DSLSTVPLSV IRQAKVLDID YLQRKGETIG2040
 2041 DLDDVDESEL DDAELPDDLP EDMEDAIARM VEEEEQFSAE VAARELPGAE EVLRTTPSKS2100
 2101 KQTSRVMPES PAQNSAPSTS GLQEPHRKRL PMPTMHPPLL RHQFPISAGP SHSPASLVPP2160
 2161 HAAQGMHPML QRHLSQTVPP PQAMHLLQNA LSAPLGQPLG CGNYGSGPNS AQHLPLVMSM2220
 2221 PSAAAAAAHL MQSAVASATA RPVETASGNP ASDPKPRGRR KKVTPLRDQL QKQQTAAAVT2280
 2281 AATSSTTPGS APSEKVKAQP LFKPHEDAAP SAPASQASVI TRMPSLLPPA HGRNHGPPSG2340
 2341 LYPSSADLAR FYGQVANQQP IPAVPGSRSP SSTSGPPRHL LRPQMPPGLP PPHASLRPTY2400
 2401 GPPPPLRGSG PPTSTPSTTT NSRPAYLHGA EHHGGPSGPP MGGVFSSGPP PARHATPHLN2460
 2461 PYRAPPIYGN PNYSPRLGGA PGTGSMRPGA VDYVAGPRGY SPYGYYPPPP PLSTPSAHAA2520
 2521 TSSVIVSAPH TLTPTNHSVP TLTHGKTPPQ QTPTQSSGPP PAAAPPPTIT SETSSHKPPL2580
 2581 ASVITSKKLT TLEAYPIRKS PIAVVADVSG PAEPTRSPAP IAEEDSGSAH DTRAPSSATG2640
 2641 TAVVGEFSGL LKSQRELCVT TNIQQQWATA LVNLTSCHHS NGCGTLWNPP DVHLEAETLG2700
 2701 RHIVLVARLH GSWGRVNWSW SRSRVNWSGS RSRVNWSWSW SRSRVNWSGR RSGKVLDGR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle