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Protein Overview: Hs2st-PA

General Information:
Name(s) found: Hs2st-PA / FBpp0080826 [FlyBase]
Description(s) found:
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  • gi|7298583|gb|AAF53800.1| Hs2st [Drosophila melanogaster] [NCBI NR]
  • gi|20455495|sp|P25722.2|HS2ST_DROME RecName: Full=Heparin sulfate O-sulfotransferase [NCBI NR]
  • gi|17137518|ref|NP_477339.1| Hs2st [Drosophila melanogaster] [NCBI NR]
  • gi|16183179|gb|AAL13651.1| GH20044p [Drosophila melanogaster] [NCBI NR]
  • (P25722) Heparin sulfate O-sulfotransferase (EC 2.8.2.-) [Swiss-Prot]
  • Heparin sulfate O-sulfotransferase OS=Drosophila melanogaster GN=Hs2st PE=2 SV=2 [Swiss-Prot]
  • The gene heparan sulfate 2-O-sulfotransferase is referred to in FlyBase by the symbol Dmel\Hs2st (CG10234, FBgn0024230). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19442830..19444761. It has the cytological map location 37E1. There is experimental evidence that it has the molecular function</span>: heparan sulfate 2-O-sulfotransferase activity. There is experimental evidence that it is involved in the biological process</span>: open tracheal system development. 4 alleles are reported. The phenotypes of these alleles are annotated with: dorsal branch; embryonic tracheal system. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG10234-PA translation from_gene[CG10234 Hs2st FBgn0024230] seq_release:3 mol_weight=41273 cds_boundaries:(2L:19,421,390..19,422,702[-]) aa_length:349 transcript_info:[CG10234-RA seq_release:3] gene_info:[gene symbol:Hs2st FBgn0024230 gene_boundaries: [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003663) Hs2st gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG10234-PA [Drosophila melanogaster]gi|16183179|gb|AAL13651.1| GH20044p [Drosophila melanogaster]gi|17137518|ref|NP_477339.1| CG10234-PA [Drosophila melanogaster]gi|20455495|sp|P25722|HS2S_DROME Heparin sulfate O-sulfotransferase [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:complement(19443304..19443547,19443631..19443851,19443912..19444050,19444109..19444427,19444493..19444619); ID=FBpp0080826; name=Hs2st-PA; parent=FBgn0024230,FBtr0081288; dbxref=FlyBase:FBpp0080826,FlyBase_Annotation_IDs:CG10234-PA,GB [fly-100309-contam.fasta]
  • GH20044p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG10234-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Hs2st CG10234-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Heparin sulfate O-sulfotransferase [nr-271106-contam.fasta]
  • type=protein; loc=2L:complement(19443304..19443547,19443631..19443851,19443912..19444050,19444109..19444427,19444493..19444619); ID=FBpp0080826; name=Hs2st-PA; parent=FBgn0024230,FBtr0081288; dbxref=FlyBase:FBpp0080826,FlyBase_Annotation_IDs:CG10234-PA,GB_protein:AAF53800.1,REFSEQ:NP_477339,GB_protein:AAF53800; MD5=ec0c42733cc3ac55d197f199542d6fe4; length=349; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:complement(19443304..19443547,19443631..19443851,19443912..19444050,19444109..19444427,19444493..19444619); ID=FBpp0080826; name=Hs2st-PA; parent=FBgn0024230,FBtr0081288; dbxref=FlyBase:FBpp0080826,FlyBase_Annotation_IDs:CG10234-PA,GB_protein:AAF53800.1,REFSEQ:NP_477339,GB_protein:AAF53800; MD5=ec0c42733cc3ac55d197f199542d6fe4; length=349; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2L:complement(19443304..19443547,19443631..19443851,19443912..19444050,19444109..19444427,19444493..19444619); ID=FBpp0080826; name=Hs2st-PA; parent=FBgn0024230,FBtr0081288; dbxref=FlyBase:FBpp0080826,FlyBase_Annotation_IDs:CG10234-PA,GB_protein:AAF53800.1,REFSEQ:NP_477339,GB_protein:AAF53800,FlyMine:FBpp0080826,modMine:FBpp0080826; MD5=ec0c42733cc3ac55d197f199542d6fe4; length=349; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:complement(join(19444493..19444619,19444109..19444427,19443912..19444050,19443631..19443851,19443304..19443547)); ID=FBpp0080826; name=Hs2st-PA; parent=FBgn0024230,FBtr0081288; dbxref=FlyBase:FBpp0080826,FlyBase_Annotation_IDs:CG10234-PA,GB_protein:AAF53800.1,REFSEQ:NP_477339,GB_protein:AAF53800,FlyMine:FBpp0080826,modMine:FBpp0080826; MD5=ec0c42733cc3ac55d197f199542d6fe4; length=349; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:complement(join(19444493..19444619,19444109..19444427,19443912..19444050,19443631..19443851,19443304..19443547)); ID=FBpp0080826; name=Hs2st-PA; parent=FBgn0024230,FBtr0081288; dbxref=FlyBase:FBpp0080826,FlyBase_Annotation_IDs:CG10234-PA,GB_protein:AAF53800.1,REFSEQ:NP_477339,GB_protein:AAF53800,FlyMine:FBpp0080826,modMine:FBpp0080826; MD5=ec0c42733cc3ac55d197f199542d6fe4; length=349; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0080826 type=protein; loc=2L:complement(join(19444493..19444619,19444109..19444427,19443912..19444050,19443631..19443851,19443304..19443547)); ID=FBpp0080826; name=Hs2st-PA; parent=FBgn0024230,FBtr0081288; dbxref=FlyBase:FBpp0080826,FlyBase_Annotation_IDs:CG10234-PA,GB_protein:AAF53800.1,REFSEQ:NP_477339,GB_protein:AAF53800,FlyMine:FBpp0080826,modMine:FBpp0080826; MD5=ec0c42733cc3ac55d197f199542d6fe4; length=349; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:complement(join(19444493..19444619,19444109..19444427,19443912..19444050,19443631..19443851,19443304..19443547)); ID=FBpp0080826; name=Hs2st-PA; parent=FBgn0024230,FBtr0081288; dbxref=FlyBase:FBpp0080826,FlyBase_Annotation_IDs:CG10234-PA,GB_protein:AAF53800.1,REFSEQ:NP_477339,GB_protein:AAF53800,UniProt/Swiss-Prot:P25722,FlyMine:FBpp0080826,modMine:FBpp0080826; MD5=ec0c42733cc3ac55d197f199542d6fe4; length=349; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 349 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: signal transduction [NAS]
    carbohydrate biosynthetic process [IEA]
    open tracheal system development [IGI][IMP]
    Molecular Function: heparan sulfate 2-O-sulfotransferase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRKLLKMWI LLRPTHWLIL IALCAVTCAG YWLLWSEIRL EHAFKPLSKL GDSLSPDQHA  60
   61 SSTTDDFDFE EHLVVLYNRV PKTGSTSFVN IAYDLCKPNK FHVLHINVTA NMHVLSLPNQ 120
  121 IQFVRNVSRW HEMKPALYHG HMAFLDFSKF QIAHKPIYIN LVRKPLDRLV SYYYFLRFGD 180
  181 NYRPNLVRKK AGNKITFDEC VVQKQPDCDP KNMWLQIPFF CGHAAECWEP GSSWALDQAK 240
  241 RNLVNEYFLV GVTEQMYEFV DLLERSLPRI FHGFREHYHN SNKSHLRVTS SKLPPSESTI 300
  301 KSIQKTKIWQ MENDLYDFAL AQFEFNKKKL MQPDNKHVQK FMYEKIRPK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle