Protein Overview: dnt-PA, FBpp0307787

General Information:
Name(s) found:	FBpp0307787 [FlyBase] dnt-PA / FBpp0080765 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|27923853\|sp\|Q9V422.2\|RYK2_DROME RecName: Full=Tyrosine-protein kinase Dnt; AltName: Full=Protein doughnut; Flags: Precursor [NCBI NR] gi\|24585175\|ref\|NP_477341.2\| doughnut on 2 [Drosophila melanogaster] [NCBI NR] gi\|22946819\|gb\|AAF53783.2\| doughnut on 2 [Drosophila melanogaster] [NCBI NR] gi\|221307663\|gb\|ACM16707.1\| FI04807p [Drosophila melanogaster] [NCBI NR] Tyrosine-protein kinase Dnt OS=Drosophila melanogaster GN=dnt PE=2 SV=2 [Swiss-Prot] type=protein; loc=2L:complement(19339165..19339276,19339355..19339651,19339770..19340934,19362659..19362839); ID=FBpp0307787; name=dnt-PB; parent=FBgn0024245,FBtr0336820; dbxref=FlyBase:FBpp0307787,FlyBase_Annotation_IDs:CG17559-PB,REFSEQ:NP_001260567,GB_protein:AGB93102; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r5.56; species=Dmel; [FlyBase] The gene doughnut on 2 is referred to in FlyBase by the symbol Dmel\dnt (CG17559, FBgn0024245). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19338676..19363224. It has the cytological map location 37D2. There is experimental evidence that it has the molecular function</span>: transmembrane receptor protein tyrosine kinase activity. There is experimental evidence that it is involved in the biological process</span>: axon guidance; signal transduction; muscle attachment; salivary gland morphogenesis. 11 alleles are reported. The phenotype of these alleles is annotated with: embryonic salivary gland. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG17559-PA translation from_gene[CG17559 dnt FBgn0024245] seq_release:3 mol_weight=64939 cds_boundaries:(2L:19,317,251..19,340,922[-]) aa_length:584 transcript_info:[CG17559-RA seq_release:3] gene_info:[gene symbol:dnt FBgn0024245 gene_boundaries:(2L: [hmr_yeast5_DM3-1_pombe.fasta] (Q9V422) Tyrosine-protein kinase Dnt precursor (EC 2.7.1.112) (Doughnut protein) [DrosMelano7227.FASTAC.txt] CG17559-PA [Drosophila melanogaster]gi\|24585175\|ref\|NP_477341.2\| CG17559-PA [Drosophila melanogaster]gi\|27923853\|sp\|Q9V422\|RYK2_DROME Tyrosine-protein kinase Dnt precursor (Doughnut protein) [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:complement(19339165..19339276,19339355..19339651,19339770..19340934,19362659..19362839); ID=FBpp0080765; name=dnt-PA; parent=FBgn0024245,FBtr0081224; dbxref=FlyBase:FBpp0080765,FlyBase_Annotation_IDs:CG17559-PA,GB_protein:AAF53783.2,R [fly-100309-contam.fasta] CG17559-PA [Drosophila melanogaster] [nr-271106-contam.fasta] doughnut on 2 CG17559-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Tyrosine-protein kinase Dnt precursor (Protein doughnut) [nr-271106-contam.fasta] type=protein; loc=2L:complement(19339165..19339276,19339355..19339651,19339770..19340934,19362659..19362839); ID=FBpp0080765; name=dnt-PA; parent=FBgn0024245,FBtr0081224; dbxref=FlyBase:FBpp0080765,FlyBase_Annotation_IDs:CG17559-PA,GB_protein:AAF53783.2,REFSEQ:NP_477341,GB_protein:AAF53783; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(19339165..19339276,19339355..19339651,19339770..19340934,19362659..19362839); ID=FBpp0080765; name=dnt-PA; parent=FBgn0024245,FBtr0081224; dbxref=FlyBase:FBpp0080765,FlyBase_Annotation_IDs:CG17559-PA,GB_protein:AAF53783.2,REFSEQ:NP_477341,GB_protein:AAF53783; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2L:complement(19339165..19339276,19339355..19339651,19339770..19340934,19362659..19362839); ID=FBpp0080765; name=dnt-PA; parent=FBgn0024245,FBtr0081224; dbxref=FlyBase:FBpp0080765,FlyBase_Annotation_IDs:CG17559-PA,GB_protein:AAF53783.2,REFSEQ:NP_477341,GB_protein:AAF53783,FlyMine:FBpp0080765,modMine:FBpp0080765; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(join(19362659..19362839,19339770..19340934,19339355..19339651,19339165..19339276)); ID=FBpp0080765; name=dnt-PA; parent=FBgn0024245,FBtr0081224; dbxref=FlyBase:FBpp0080765,FlyBase_Annotation_IDs:CG17559-PA,GB_protein:AAF53783.2,REFSEQ:NP_477341,GB_protein:AAF53783,FlyMine:FBpp0080765,modMine:FBpp0080765; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(19362659..19362839,19339770..19340934,19339355..19339651,19339165..19339276)); ID=FBpp0307787; name=dnt-PB; parent=FBgn0024245,FBtr0336820; dbxref=FlyBase:FBpp0307787,FlyBase_Annotation_IDs:CG17559-PB,REFSEQ:NP_001260567,GB_protein:AGB93102; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(19362659..19362839,19339770..19340934,19339355..19339651,19339165..19339276)); ID=FBpp0080765; name=dnt-PA; parent=FBgn0024245,FBtr0081224; dbxref=FlyBase:FBpp0080765,FlyBase_Annotation_IDs:CG17559-PA,GB_protein:AAF53783.2,REFSEQ:NP_477341,GB_protein:AAF53783,FlyMine:FBpp0080765,modMine:FBpp0080765; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:complement(join(19362659..19362839,19339770..19340934,19339355..19339651,19339165..19339276)); ID=FBpp0307787; name=dnt-PB; parent=FBgn0024245,FBtr0336820; dbxref=FlyBase:FBpp0307787,FlyBase_Annotation_IDs:CG17559-PB,REFSEQ:NP_001260567,GB_protein:AGB93102; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q9V422, Doughnut on 2, isoform B OS=Drosophila melanogaster GN=dnt PE=4 SV=1 [DROME.fasta.20160308] FBpp0080765 type=protein; loc=2L:complement(join(19362659..19362839,19339770..19340934,19339355..19339651,19339165..19339276)); ID=FBpp0080765; name=dnt-PA; parent=FBgn0024245,FBtr0081224; dbxref=FlyBase:FBpp0080765,FlyBase_Annotation_IDs:CG17559-PA,GB_protein:AAF53783.2,REFSEQ:NP_477341,GB_protein:AAF53783,FlyMine:FBpp0080765,modMine:FBpp0080765; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0307787 type=protein; loc=2L:complement(join(19362659..19362839,19339770..19340934,19339355..19339651,19339165..19339276)); ID=FBpp0307787; name=dnt-PB; parent=FBgn0024245,FBtr0336820; dbxref=FlyBase:FBpp0307787,FlyBase_Annotation_IDs:CG17559-PB,REFSEQ:NP_001260567,GB_protein:AGB93102; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(19362659..19362839,19339770..19340934,19339355..19339651,19339165..19339276)); ID=FBpp0080765; name=dnt-PA; parent=FBgn0024245,FBtr0081224; dbxref=FlyBase:FBpp0080765,FlyBase_Annotation_IDs:CG17559-PA,GB_protein:AAF53783.2,REFSEQ:NP_477341,GB_protein:AAF53783,UniProt/Swiss-Prot:Q9V422,FlyMine:FBpp0080765,modMine:FBpp0080765; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:complement(join(19362659..19362839,19339770..19340934,19339355..19339651,19339165..19339276)); ID=FBpp0307787; name=dnt-PB; parent=FBgn0024245,FBtr0336820; dbxref=FlyBase:FBpp0307787,FlyBase_Annotation_IDs:CG17559-PB,REFSEQ:NP_001260567,GB_protein:AGB93102,UniProt/Swiss-Prot:Q9V422; MD5=d0f747f8b1ec090e9d1a41494530bdb8; length=584; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	584 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [IEA] integral to membrane [ISS] plasma membrane [ISS]
Biological Process:	signal transduction [IMP] axon guidance [IMP] Wnt receptor signaling pathway [IEA] protein amino acid phosphorylation [ISS][NAS] muscle attachment [IMP] salivary gland morphogenesis [IMP]
Molecular Function:	ATP binding [IEA] protein tyrosine kinase activity [NAS] transmembrane receptor protein tyrosine kinase activity [IGI][ISS] Wnt-protein binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESVNKCGKS ASTRNCTVKM SRKMWVLSLL ALAALQLHSG SEVAAHLNVF LNPVEVMRLL  60
   61 GVSAEVYYVR EGHINNYALN FIVPVPANVK DISFTWQSLA GRGLPYSINV VSSDQEVLPR 120
  121 PAINVSHSGE IPTTIQTWSI ALKCSGLKAA EVDVTVSLEV VLNRSLNNVT HLVFRRKKIC 180
  181 LMNDSAEDLS EDVDDPQLLE TVMLPPTGLI TLVVGVSVAM GSVCLLLMIA YCVKGAANKR 240
  241 QHHQHGGQPM RTSSFQRLNT HPPCQSSMGS AAYMTPSIIA PIHGSSLPRK VPVSVEQQHP 300
  301 EELHRRISEL TVERCRVRLS SLLQEGTFGR VYRGTYNDTQ DVLVKTVAQH ASQMQVLLLL 360
  361 QEGMLLYGAS HPGILSVLGV SIEDHTTPFV LYPALNNTRN LKQFLLDPAC ARTVTTIQIV 420
  421 MMASQLSMAL DHLHSHGVVH KDIATRNCVI DDQLRVKLSD SSLSRDLFPS DYNCLGDSEN 480
  481 RPVKWMSLEA LQHKQFSEAS DSWAFGVLMW ELCTSAKQPY AEVDPFEMEH YLKDGYRLAQ 540
  541 PFNCPDELFT IMAYCWALLP AERPTFAQLQ SCLSEFYSQI TRYV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: dnt-PA, FBpp0307787

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: