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Protein Overview: drl-PA

General Information:
Name(s) found: drl-PA / FBpp0080736 [FlyBase]
Description(s) found:
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  • gi|984566|gb|AAA75347.1| derailed receptor protein tyrosine kinase [NCBI NR]
  • gi|7298558|gb|AAF53776.1| derailed [Drosophila melanogaster] [NCBI NR]
  • gi|27923851|sp|Q27324.1|RYK1_DROME RecName: Full=Tyrosine-protein kinase Drl; AltName: Full=Protein derailed; Flags: Precursor [NCBI NR]
  • pir||S58885 derailed receptor protein tyrosine kinase - fruit fly (Drosophila melanogaster) [NCBI NR]
  • gi|17137162|ref|NP_477139.1| derailed [Drosophila melanogaster] [NCBI NR]
  • gi|15292015|gb|AAK93276.1| LD35237p [Drosophila melanogaster] [NCBI NR]
  • gi|1040976|gb|AAA79949.1| receptor tyrosine kinase [NCBI NR]
  • Tyrosine-protein kinase Drl OS=Drosophila melanogaster GN=drl PE=2 SV=1 [Swiss-Prot]
  • The gene derailed is referred to in FlyBase by the symbol Dmel\drl (CG17348, FBgn0015380). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19190346..19208615. It has the cytological map location 37C7. There is experimental evidence that it has the molecular function</span>: Wnt-protein binding. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; axon guidance; learning or memory; memory; haltere development; Wnt receptor signaling pathway; signal transduction; muscle attachment; salivary gland morphogenesis. 35 alleles are reported. The phenotypes of these alleles are annotated with 51 unique terms, many of which group under: abdominal transverse muscle; hypodermal muscle of larval abdomen; organ system; nervous system; multi-cell-component structure; adult segment; embryonic nervous system; adult brain; larval abdominal segment 5; commissure. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG17348-PA translation from_gene[CG17348 drl FBgn0015380] seq_release:3 mol_weight=68313 cds_boundaries:(2L:19,168,812..19,185,817[+]) aa_length:610 transcript_info:[CG17348-RA seq_release:3] gene_info:[gene symbol:drl synonyms:[CG10758] FBgn0015380 g [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q27324) Tyrosine-protein kinase Drl precursor (EC 2.7.1.112) (Derailed protein) [DrosMelano7227.FASTAC.txt]
  • (AE003662) drl gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG17348-PA [Drosophila melanogaster]gi|15292015|gb|AAK93276.1| LD35237p [Drosophila melanogaster]gi|17137162|ref|NP_477139.1| CG17348-PA [Drosophila melanogaster]gi|2133649|pir||S58885 derailed receptor protein tyrosine kinase - fruit fly (Drosophila [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:join(19190729..19190834,19205721..19207038,19207205..19207501,19207626..19207737); ID=FBpp0080736; name=drl-PA; parent=FBgn0015380,FBtr0081195; dbxref=GB_protein:AAF53776.1,FlyBase:FBpp0080736,FlyBase_Annotation_IDs:CG17348-PA,REFSEQ: [fly-100309-contam.fasta]
  • derailed receptor protein tyrosine kinase [nr-271106-contam.fasta]
  • Tyrosine-protein kinase Drl precursor (Protein derailed) [nr-271106-contam.fasta]
  • LD35237p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • derailed CG17348-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG17348-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • receptor tyrosine kinase [nr-271106-contam.fasta]
  • type=protein; loc=2L:join(19190729..19190834,19205721..19207038,19207205..19207501,19207626..19207737); ID=FBpp0080736; name=drl-PA; parent=FBgn0015380,FBtr0081195; dbxref=GB_protein:AAF53776.1,FlyBase:FBpp0080736,FlyBase_Annotation_IDs:CG17348-PA,REFSEQ:NP_477139,GB_protein:AAF53776; MD5=c6930b2d58c7370712e91242040e16d2; length=610; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:join(19190729..19190834,19205721..19207038,19207205..19207501,19207626..19207737); ID=FBpp0080736; name=drl-PA; parent=FBgn0015380,FBtr0081195; dbxref=GB_protein:AAF53776.1,FlyBase:FBpp0080736,FlyBase_Annotation_IDs:CG17348-PA,REFSEQ:NP_477139,GB_protein:AAF53776; MD5=c6930b2d58c7370712e91242040e16d2; length=610; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Tyrosine-protein kinase Drl OS=Drosophila melanogaster GN=drl PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:join(19190729..19190834,19205721..19207038,19207205..19207501,19207626..19207737); ID=FBpp0080736; name=drl-PA; parent=FBgn0015380,FBtr0081195; dbxref=GB_protein:AAF53776.1,FlyBase:FBpp0080736,FlyBase_Annotation_IDs:CG17348-PA,REFSEQ:NP_477139,GB_protein:AAF53776,FlyMine:FBpp0080736,modMine:FBpp0080736; MD5=c6930b2d58c7370712e91242040e16d2; length=610; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:join(19190729..19190834,19205721..19207038,19207205..19207501,19207626..19207737); ID=FBpp0080736; name=drl-PA; parent=FBgn0015380,FBtr0081195; dbxref=GB_protein:AAF53776.1,FlyBase:FBpp0080736,FlyBase_Annotation_IDs:CG17348-PA,REFSEQ:NP_477139,GB_protein:AAF53776,FlyMine:FBpp0080736,modMine:FBpp0080736; MD5=c6930b2d58c7370712e91242040e16d2; length=610; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(19190729..19190834,19205721..19207038,19207205..19207501,19207626..19207737); ID=FBpp0080736; name=drl-PA; parent=FBgn0015380,FBtr0081195; dbxref=GB_protein:AAF53776.1,FlyBase:FBpp0080736,FlyBase_Annotation_IDs:CG17348-PA,REFSEQ:NP_477139,GB_protein:AAF53776,FlyMine:FBpp0080736,modMine:FBpp0080736; MD5=c6930b2d58c7370712e91242040e16d2; length=610; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0080736 type=protein; loc=2L:join(19190729..19190834,19205721..19207038,19207205..19207501,19207626..19207737); ID=FBpp0080736; name=drl-PA; parent=FBgn0015380,FBtr0081195; dbxref=GB_protein:AAF53776.1,FlyBase:FBpp0080736,FlyBase_Annotation_IDs:CG17348-PA,REFSEQ:NP_477139,GB_protein:AAF53776,FlyMine:FBpp0080736,modMine:FBpp0080736; MD5=c6930b2d58c7370712e91242040e16d2; length=610; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:join(19190729..19190834,19205721..19207038,19207205..19207501,19207626..19207737); ID=FBpp0080736; name=drl-PA; parent=FBgn0015380,FBtr0081195; dbxref=GB_protein:AAF53776.1,FlyBase:FBpp0080736,FlyBase_Annotation_IDs:CG17348-PA,REFSEQ:NP_477139,GB_protein:AAF53776,UniProt/Swiss-Prot:Q27324,FlyMine:FBpp0080736,modMine:FBpp0080736; MD5=c6930b2d58c7370712e91242040e16d2; length=610; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 610 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IEA]
    plasma membrane [ISS]
    Biological Process: signal transduction [IMP]
    haltere development [IGI]
    axon guidance [IMP]
    Wnt receptor signaling pathway [IGI][IPI]
    olfactory learning [IMP][TAS]
    axon midline choice point recognition [TAS]
    protein amino acid phosphorylation [IEA][NAS]
    memory [IMP]
    muscle attachment [IMP]
    learning or memory [IMP]
    salivary gland morphogenesis [IMP]
    Molecular Function: ATP binding [IEA]
    protein tyrosine kinase activity [NAS]
    transmembrane receptor protein tyrosine kinase activity [IEA][ISS][NAS]
    Wnt-protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPNLLTIGL LLTLIASGQA HLNIFLNLHE VLRLIGVSAE LYYVREGAIN DYALNFAVPV  60
   61 PANISDVTFT WQSLVDHPLP YSINIATSDT EVLPRPILNI SRIGDVPVEP QTWGIALKCS 120
  121 GTRNAEVTVT INVEVILDRA TNNNTNLIFK RKKICLREEQ DSAHEEYDDD DLDLLQTARK 180
  181 GHGGDIHYVD RNDEHVVANG HQAPEKQRPV VTESPVGRGN SGGSKRDFDP MLRENLVPPA 240
  241 SGLVTLIVGG ILALVLVSTL ILIAYCAKGP SKRHPSNGVH LIKTSSFQRL PTISSTAHNS 300
  301 IYVCPSTITP TYATLTRPFR EYEHEPEEFN RRLQELTVQK CRVRLSCLVQ EGNFGRIYRG 360
  361 TYNDCQEVLV KTVAQHASQL QVNLLLQESM MLYEASHPNV LSVLGISIED YATPFVLYAA 420
  421 TGSVRNLKSF LQDPSYARSV TTIQTVLMGS QLAMAMEHLH NHGVIHKDIA ARNCVIDDQL 480
  481 RVKLTDSALS RDLFPGDYNS LGDGEYRPIK WLSLEALQKS HYNEGSDVWS FGVLMWEMCT 540
  541 LGKLPYAEID PYEMEHYLKD GYRLAQPFNC PDELFTIMAY CWASMPAERP SFSQLQICLS 600
  601 EFHTQITRYV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle