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Protein Overview: Nak-PA, FBpp0309286

General Information:
Name(s) found: FBpp0309286 [FlyBase]
Nak-PA / FBpp0080729 [FlyBase]
Description(s) found:
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  • gi|22946792|gb|AAF53727.2| Numb-associated kinase, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|17137206|ref|NP_477165.1| Numb-associated kinase, isoform A [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=2L:complement(18958300..18960680,18962885..18963115,18963171..18963469,18963993..18964564,18964631..18965183,18965259..18965392,18965456..18965589,18968253..18968415); ID=FBpp0309286; name=Nak-PD; parent=FBgn0015772,FBtr0340325; dbxref=FlyBase:FBpp0309286,FlyBase_Annotation_IDs:CG10637-PD; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r5.56; species=Dmel; [FlyBase]
  • The gene Numb-associated kinase is referred to in FlyBase by the symbol Dmel\Nak (CG10637, FBgn0015772). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:18957900..18968721. It has the cytological map location 37B7. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: asymmetric cell division. 5 alleles are reported. The phenotypes of these alleles are annotated with: head sensillum; adult mesothoracic sensillum; wing sensillum. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • >CG10637-PA translation from_gene[CG10637 Nak FBgn0015772] seq_release:3 mol_weight=159670 cds_boundaries:(2L:18,936,386..18,946,498[-]) aa_length:1488 transcript_info:[CG10637-RA seq_release:3] gene_info:[gene symbol:Nak FBgn0015772 gene_boundaries:(2 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VJ30) CG10637 protein [DrosMelano7227.FASTAC.txt]
  • CG10637-PA, isoform A [Drosophila melanogaster]gi|17137206|ref|NP_477165.1| CG10637-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:complement(18958300..18960680,18962885..18963115,18963171..18963469,18963993..18964564,18964631..18965183,18965259..18965392,18965456..18965589,18968253..18968415); ID=FBpp0080729; name=Nak-PA; parent=FBgn0015772,FBtr0081187; dbxref=F [fly-100309-contam.fasta]
  • CG10637-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Numb-associated kinase CG10637-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:complement(18958300..18960680,18962885..18963115,18963171..18963469,18963993..18964564,18964631..18965183,18965259..18965392,18965456..18965589,18968253..18968415); ID=FBpp0080729; name=Nak-PA; parent=FBgn0015772,FBtr0081187; dbxref=FlyBase:FBpp0080729,FlyBase_Annotation_IDs:CG10637-PA,GB_protein:AAF53727.2,REFSEQ:NP_477165,GB_protein:AAF53727; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:complement(18958300..18960680,18962885..18963115,18963171..18963469,18963993..18964564,18964631..18965183,18965259..18965392,18965456..18965589,18968253..18968415); ID=FBpp0080729; name=Nak-PA; parent=FBgn0015772,FBtr0081187; dbxref=FlyBase:FBpp0080729,FlyBase_Annotation_IDs:CG10637-PA,GB_protein:AAF53727.2,REFSEQ:NP_477165,GB_protein:AAF53727; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Numb-associated kinase, isoform A OS=Drosophila melanogaster GN=Nak PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:complement(18958300..18960680,18962885..18963115,18963171..18963469,18963993..18964564,18964631..18965183,18965259..18965392,18965456..18965589,18968253..18968415); ID=FBpp0080729; name=Nak-PA; parent=FBgn0015772,FBtr0081187; dbxref=FlyBase:FBpp0080729,FlyBase_Annotation_IDs:CG10637-PA,GB_protein:AAF53727.2,REFSEQ:NP_477165,GB_protein:AAF53727,FlyMine:FBpp0080729,modMine:FBpp0080729; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:complement(join(18968253..18968415,18965456..18965589,18965259..18965392,18964631..18965183,18963993..18964564,18963171..18963469,18962885..18963115,18958300..18960680)); ID=FBpp0080729; name=Nak-PA; parent=FBgn0015772,FBtr0081187; dbxref=FlyBase:FBpp0080729,FlyBase_Annotation_IDs:CG10637-PA,GB_protein:AAF53727.2,REFSEQ:NP_477165,GB_protein:AAF53727,FlyMine:FBpp0080729,modMine:FBpp0080729; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:complement(join(18968253..18968415,18965456..18965589,18965259..18965392,18964631..18965183,18963993..18964564,18963171..18963469,18962885..18963115,18958300..18960680)); ID=FBpp0309286; name=Nak-PD; parent=FBgn0015772,FBtr0340325; dbxref=FlyBase:FBpp0309286,FlyBase_Annotation_IDs:CG10637-PD,GB_protein:AAN11019,REFSEQ:NP_477166; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:complement(join(18968253..18968415,18965456..18965589,18965259..18965392,18964631..18965183,18963993..18964564,18963171..18963469,18962885..18963115,18958300..18960680)); ID=FBpp0080729; name=Nak-PA; parent=FBgn0015772,FBtr0081187; dbxref=FlyBase:FBpp0080729,FlyBase_Annotation_IDs:CG10637-PA,GB_protein:AAF53727.2,REFSEQ:NP_477165,GB_protein:AAF53727,FlyMine:FBpp0080729,modMine:FBpp0080729; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2L:complement(join(18968253..18968415,18965456..18965589,18965259..18965392,18964631..18965183,18963993..18964564,18963171..18963469,18962885..18963115,18958300..18960680)); ID=FBpp0309286; name=Nak-PD; parent=FBgn0015772,FBtr0340325; dbxref=FlyBase:FBpp0309286,FlyBase_Annotation_IDs:CG10637-PD,GB_protein:AAN11019,REFSEQ:NP_477166; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Numb-associated kinase, isoform A OS=Drosophila melanogaster GN=Nak PE=1 SV=2 [DROME.fasta.20160308]
  • FBpp0080729 type=protein; loc=2L:complement(join(18968253..18968415,18965456..18965589,18965259..18965392,18964631..18965183,18963993..18964564,18963171..18963469,18962885..18963115,18958300..18960680)); ID=FBpp0080729; name=Nak-PA; parent=FBgn0015772,FBtr0081187; dbxref=FlyBase:FBpp0080729,FlyBase_Annotation_IDs:CG10637-PA,GB_protein:AAF53727.2,REFSEQ:NP_477165,GB_protein:AAF53727,FlyMine:FBpp0080729,modMine:FBpp0080729; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0309286 type=protein; loc=2L:complement(join(18968253..18968415,18965456..18965589,18965259..18965392,18964631..18965183,18963993..18964564,18963171..18963469,18962885..18963115,18958300..18960680)); ID=FBpp0309286; name=Nak-PD; parent=FBgn0015772,FBtr0340325; dbxref=FlyBase:FBpp0309286,FlyBase_Annotation_IDs:CG10637-PD,GB_protein:AAN11019,REFSEQ:NP_477166; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:complement(join(18968253..18968415,18965456..18965589,18965259..18965392,18964631..18965183,18963993..18964564,18963171..18963469,18962885..18963115,18958300..18960680)); ID=FBpp0080729; name=Nak-PA; parent=FBgn0015772,FBtr0081187; dbxref=FlyBase:FBpp0080729,FlyBase_Annotation_IDs:CG10637-PA,GB_protein:AAF53727.2,REFSEQ:NP_477165,GB_protein:AAF53727,UniProt/TrEMBL:Q9VJ30,FlyMine:FBpp0080729,modMine:FBpp0080729; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2L:complement(join(18968253..18968415,18965456..18965589,18965259..18965392,18964631..18965183,18963993..18964564,18963171..18963469,18962885..18963115,18958300..18960680)); ID=FBpp0309286; name=Nak-PD; parent=FBgn0015772,FBtr0340325; dbxref=FlyBase:FBpp0309286,FlyBase_Annotation_IDs:CG10637-PD,GB_protein:AAN11019,REFSEQ:NP_477166,UniProt/TrEMBL:Q9VJ30; MD5=e1c80a95d96e4b8846ffcf7a2af18e85; length=1488; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1488 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: asymmetric cell division [IMP][IPI]
    protein amino acid phosphorylation [ISS][NAS]
    Molecular Function: ATP binding [IEA]
    protein binding [IPI]
    protein kinase activity [NAS]
    protein serine/threonine kinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKILSKFER NENSRLENPP NSSSSSSSNE KNSFVGKVFT VGRVTVTVED VLAEGGFAMV  60
   61 FLARGNGGGS SSATKYALKR MYVNNEHDLN VAKREIQIAS NLSGHKNIIG YVDSSITPTG 120
  121 NGVCEVLLLM PYCKHHMLAM MNARLHVGFT EPEVLNIFCD IAEAVSRLHY CQTPIIHRDL 180
  181 KVENILQTDA GNFVLCDFGS ATAKTLNPQQ HGVTVVQEEI QKYTTLSYRA PEMIDLYGGK 240
  241 SITTKADIWA LGCMLYKLCF FSLPFGESTL AIQNGQFSIP DSSKYSKGMH QLIKYMLEPD 300
  301 MEKRPNIWQV CEVAFRLAGK DNPVQNLHKT PIPNFDLLVV PPFESEAKRI SAAASKAAKA 360
  361 QNVSVVEAGT SVAPRSRPKG SSSVHGGNPL GLGLPPSPSP RQNITSPQPQ PQPVVEQFQA 420
  421 NFPAMPPAVP PPPQAVTPAA PAASKLFESS GYPDPFNEPA AAVIPTEFLP AAEEPNKEEV 480
  481 PQDLNVIAGT PTKSMLTPPK PSGGGGHRRN VSDTSAFNKT FANETSQFLA PFNNNLAAMG 540
  541 DGQQTLASAA SNPGIYASST ANSAAVSISE LMKPGQTAVE KRVEAWNPFE EEQPFSQMTE 600
  601 DHIFEAEFDK IRQRGSQGSI TAKSASTTST LTPTEQIPSA VVAPVTAAPG AVPPPPIAAA 660
  661 VSPYPSQVSE DPFGSAPFSL PPGLREKASS LRKTGAKFIG VSSGGTGGGV ATPIGLVAGG 720
  721 ANTATSSNSS KWMLSPTLEV SSEEKTSLIS KLKTDSECGI PGAVGGAGEG VSGYVKLPVE 780
  781 DRNKYEKLRS KDQPTSDDSD SEASEFFQQD SDEGGGGIFR QMQMVTSNLP ETIHKIQQVA 840
  841 YHKVDKTAHL PIVKKLRDKT KKPTTAAHQA AQQLNLMAAA VAAQAEEAAK AAESDGDSIG 900
  901 SASDLRAEDD DLFDENPRQT QAKQRRPLPT EMDGISESVK TCSSSAYHAE CESVTTHEDD 960
  961 VRSRVVVKVR MRKKDRALVT ATGDPSAPSE ELSPTSSDLL HKFGDRPLLL DDELDYGSGE1020
 1021 SKSSTESPVA PILPTNPDVQ ESEEDVFALA PFKLPVGVPL KRKTKPKAKP KPSEPEMWTS1080
 1081 TPVKSAAVGD PSTNFASFPA QLTPTNNVGN SAQLDEFNEP IFNPFQENAQ NTQSGETNQC1140
 1141 DLFGLEPFPQ VIRTIEQNPQ HHQIHQFPSH NNNNNVIKVP ASVSVALPAS VPVSVSVNSS1200
 1201 APQLVTINHS IIINKTPEPP MNYNNNNNNQ TAKSSGTSSV YVNVPSFSSM STSSCSINQP1260
 1261 QSSPAAVIPV QAPLPVPVPA PVSVPAVPVP IPAVVTHLRP LLPIADNAYV QISQDRCSDF1320
 1321 TPDDEEEPVV LRDADVVADG IGIPTPAKPK KEKSNLAVRV LPGKLTQKVK GHSYKKVSAA1380
 1381 ALGSTSSLSS GSKQKHQRLQ YQSHDDDDDE QDQDENRGAG GGRNFQSNTI QNSAKTGFSN1440
 1441 MSFEDFPSDQ EMDRLSRTIP FEVVRNEKML LEAEKKFGSL KRRNNLFS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle