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Protein Overview: FBpp0307137, her-PA

General Information:
Name(s) found: FBpp0307137 [FlyBase]
her-PA / FBpp0080440 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=2L:join(16677383..16678249,16678318..16678581,16678643..16678975); ID=FBpp0307137; name=her-PB; parent=FBgn0001185,FBtr0335138; dbxref=REFSEQ:NP_001260506,GB_protein:AGB93041,FlyBase:FBpp0307137,FlyBase_Annotation_IDs:CG4694-PB; MD5=ff7558c2b29ed7aa5c99b1471b6ca555; length=487; release=r5.56; species=Dmel; [FlyBase]
  • The gene hermaphrodite is referred to in FlyBase by the symbol Dmel\her (CG4694, FBgn0001185). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:16677210..16679932. It has the cytological map location 36A10. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: sex determination. 11 alleles are reported. The phenotypes of these alleles are annotated with: epiproct; male terminalia; abdominal sternite 6; male abdominal 5 muscle; female terminalia. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 487 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: sex differentiation [TAS]
    female somatic sex determination [NAS]
    sex determination [IMP]
    sex determination, primary response to X:A ratio [TAS]
    positive regulation of transcription from RNA polymerase II promoter [TAS]
    regulation of transcription from RNA polymerase II promoter [TAS]
    Molecular Function: DNA binding [TAS]
    transcription factor activity [ISS]
    zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSADRDSVE EEYGSCSAWK FRCSVDRCPY RTNRPYNLAR HEESHIGITQ SKLYGCPVCV  60
   61 YNTDKASNLK RHVSIKHPGC KKRPPEAQHK DRNAKLQCLV MGCRYETNRP YDLKRHLMVH 120
  121 NNPEKSHRTF KCSLCTYSSD RKANLKRHHE LRHSGIEEAI QTAEELRQEM LLEKQMLKEH 180
  181 KLKYQITEKQ DLKNLKLKDQ KQKVQMLRDQ QPKQRQKKEQ LLEDQSPVLN KQLEHGNIPL 240
  241 KEALVGSMKY DEESLEFVYE ELQEEEQPPI ITISNPQILH GDIRDKHVIA VNVDGQLRWF 300
  301 QSIDPPPGAP TKLELPIKST SISVQQQMDE LDDELAMSLA EEDQQDEFLV PMLSGEEPVK 360
  361 IKQSSLTDLA WSWSTPDAVH HISPKAELKK DLKAGDADTD FPDWWDDGKY TKMQKNQTFA 420
  421 KHSKKPSQEN VQRILRIIYD IYYKPFKEDR KQFEAFQIKD SWLCATRMTR MQIIKDMYSK 480
  481 QGTLSQT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle