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Protein Overview: FBpp0303862, FBp...

General Information:
Name(s) found: FBpp0303863 [FlyBase]
FBpp0303862 [FlyBase]
FBpp0303861 [FlyBase]
twe-PA / FBpp0080412 [FlyBase]
Description(s) found:
Found 46 descriptions.
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  • type=protein; loc=2L:complement(16260225..16261505); ID=FBpp0303863; name=twe-PD; parent=FBgn0002673,FBtr0331446; dbxref=FlyBase:FBpp0303863,FlyBase_Annotation_IDs:CG4965-PD,REFSEQ:NP_001260493,GB_protein:AGB93028; MD5=3ec6736681a22b5d32d2e1d6577a7687; length=426; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2L:complement(16260225..16261505); ID=FBpp0303862; name=twe-PC; parent=FBgn0002673,FBtr0331445; dbxref=FlyBase:FBpp0303862,FlyBase_Annotation_IDs:CG4965-PC,REFSEQ:NP_001260492,GB_protein:AGB93027; MD5=3ec6736681a22b5d32d2e1d6577a7687; length=426; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2L:complement(16260225..16261505); ID=FBpp0303861; name=twe-PB; parent=FBgn0002673,FBtr0331444; dbxref=FlyBase:FBpp0303861,FlyBase_Annotation_IDs:CG4965-PB,REFSEQ:NP_001260491,GB_protein:AGB93026; MD5=3ec6736681a22b5d32d2e1d6577a7687; length=426; release=r5.56; species=Dmel; [FlyBase]
  • The gene twine is referred to in FlyBase by the symbol Dmel\twe (CG4965, FBgn0002673). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:16259416..16261875. It has the cytological map location 35F1. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of meiotic cell cycle; spindle assembly involved in male meiosis; pole cell formation; regulation of syncytial blastoderm mitotic cell cycle; meiotic nuclear envelope disassembly; embryonic development; male meiosis; cellularization; spindle assembly involved in female meiosis; spermatogenesis. 16 alleles are reported. The phenotypes of these alleles are annotated with: yolk; trichogen cell; oocyte; spindle; tormogen cell; spermatocyte; oocyte nucleus. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 426 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: embryonic development [IMP]
    male meiosis [IMP]
    spermatogenesis [IMP][TAS]
    protein amino acid dephosphorylation [IEA][ISS][NAS]
    spindle assembly involved in male meiosis [IMP]
    pole cell formation [IMP]
    spindle assembly involved in female meiosis [IMP]
    regulation of syncytial blastoderm mitotic cell cycle [IMP]
    cellularization [IMP]
    meiotic G2/MI transition [NAS][TAS]
    regulation of meiotic cell cycle [IMP]
    M phase of mitotic cell cycle [IEA]
    meiotic nuclear envelope disassembly [IMP]
    Molecular Function: protein tyrosine phosphatase activity [IEA][ISS][NAS]
    protein tyrosine/serine/threonine phosphatase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASKRLMLDV EEEDDESGAC GQENFDPHDA DMEYQAKRRK SAVQETPLQW MLKRHIPAST  60
   61 TVLSPITELS QNMNGARLDG TPKSTQRIPA NRTLNNFNSL SSRTLGSFSS SCSSYESGNS 120
  121 LDDEYMDMFE MESAENHNLE LPDDLEVLLS GQLKSESNLE EMSNKKGSLR RCLSMYPSEQ 180
  181 PEEAVQEPDQ ETNMPMKKMQ RKTLSMNDAE IMRALGDEPE LIGDLSKPCT LPCLATGIRH 240
  241 RDLKTISSDT LARLIQGEFD EQLGSQGGYE IIDCRYPYEF LGGHIRGAKN LYTRGQIQEA 300
  301 FPTLTSNQEN RRIYVFHCEF SSERGPKLLR YLRSNDRSQH THNYPALDYP ELYILHNGYK 360
  361 EFFGLYSQLC QPSQYVPMLA PAHNDEFRYF RAKTKSWQCG EGGDSGIGGG GSRGLRKSRS 420
  421 RLLYAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle