Protein Overview: FBpp0310261, Smg...

General Information:
Name(s) found:	FBpp0310261 [FlyBase] Smg5-PB / FBpp0080139 [FlyBase] Smg5-PA / FBpp0080138 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7298113\|gb\|AAF53352.1\| Smg5, isoform B [Drosophila melanogaster] [NCBI NR] gi\|7298112\|gb\|AAF53351.1\| Smg5, isoform A [Drosophila melanogaster] [NCBI NR] gb\|AAF44833.1\| symbol=anon-34Ea; synonym=BG:DS08220.2; cDNA=method:''sim4'', score:''1000.0'', desc:''LD02558 LD Drosophila melanogaster embryo BlueScript Drosophila melanogaster cDNA clone, full length mRNA sequence from BDGP''; cDNA=method:''sim4'', sco [NCBI NR] gi\|30014095\|emb\|CAD89222.1\| SMG5 protein [Drosophila melanogaster] [NCBI NR] gi\|24584229\|ref\|NP_723851.1\| Smg5, isoform B [Drosophila melanogaster] [NCBI NR] gi\|20129507\|ref\|NP_609685.1\| Smg5, isoform A [Drosophila melanogaster] [NCBI NR] gi\|159884161\|gb\|ABX00759.1\| LD36341p [Drosophila melanogaster] [NCBI NR] type=protein; loc=2L:complement(13899822..13900063,13900143..13900301,13900632..13901981,13902075..13903717,13903781..13903920); ID=FBpp0310261; name=Smg5-PC; parent=FBgn0019890,FBtr0343669; dbxref=FlyBase:FBpp0310261,FlyBase_Annotation_IDs:CG8954-PC; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r5.56; species=Dmel; [FlyBase] The gene Smg5 is referred to in FlyBase by the symbol Dmel\Smg5 (CG8954, FBgn0019890). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:13899353..13904659. It has the cytological map location 34E2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. 13 alleles are reported. The phenotype of these alleles is annotated with: intersegmental nerve. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG8954-PB translation from_gene[CG8954 CG8954 FBgn0019890] seq_release:3 mol_weight=135315 cds_boundaries:(2L:13,881,977..13,886,072[-]) aa_length:1177 transcript_info:[CG8954-RB seq_release:3] gene_info:[gene symbol:CG8954 FBgn0019890 gene_boundaries [hmr_yeast5_DM3-1_pombe.fasta] >CG8954-PA translation from_gene[CG8954 CG8954 FBgn0019890] seq_release:3 mol_weight=135315 cds_boundaries:(2L:13,881,977..13,886,072[-]) aa_length:1177 transcript_info:[CG8954-RA seq_release:3] gene_info:[gene symbol:CG8954 FBgn0019890 gene_boundaries [hmr_yeast5_DM3-1_pombe.fasta] (Q9V414) ANON-34EA protein (SMG5 protein) [DrosMelano7227.FASTAC.txt] (AE003641) CG8954 gene product [alt 1] [Drosophila melanogaster] [yeastflysequest.fasta] (AE003641) CG8954 gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta] CG8954-PB, isoform B [Drosophila melanogaster]gi\|7298112\|gb\|AAF53351.1\| CG8954-PA, isoform A [Drosophila melanogaster]gi\|30014095\|emb\|CAD89222.1\| SMG5 protein [Drosophila melanogaster]gi\|7287795\|gb\|AAF44833.1\| symbol=anon-34Ea; synonym=BG:DS08220.2; cD [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:complement(13899822..13900063,13900143..13900301,13900632..13901981,13902075..13903717,13903781..13903920); ID=FBpp0080138; name=Smg5-PA; parent=FBgn0019890,FBtr0080561; dbxref=FlyBase:FBpp0080138,FlyBase_Annotation_IDs:CG8954-PA,GB_p [fly-100309-contam.fasta] type=protein; loc=2L:complement(13899822..13900063,13900143..13900301,13900632..13901981,13902075..13903717,13903781..13903920); ID=FBpp0080139; name=Smg5-PB; parent=FBgn0019890,FBtr0080562; dbxref=FlyBase:FBpp0080139,FlyBase_Annotation_IDs:CG8954-PB,GB_p [fly-100309-contam.fasta] CG8954-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] Smg5 CG8954-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Smg5 CG8954-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] SMG5 protein [Drosophila melanogaster] [nr-271106-contam.fasta] CG8954-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:complement(13899822..13900063,13900143..13900301,13900632..13901981,13902075..13903717,13903781..13903920); ID=FBpp0080138; name=Smg5-PA; parent=FBgn0019890,FBtr0080561; dbxref=FlyBase:FBpp0080138,FlyBase_Annotation_IDs:CG8954-PA,GB_protein:AAF53351.1,REFSEQ:NP_609685,GB_protein:AAF53351; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(13899822..13900063,13900143..13900301,13900632..13901981,13902075..13903717,13903781..13903920); ID=FBpp0080139; name=Smg5-PB; parent=FBgn0019890,FBtr0080562; dbxref=FlyBase:FBpp0080139,FlyBase_Annotation_IDs:CG8954-PB,GB_protein:AAF53352.1,REFSEQ:NP_723851,GB_protein:AAF53352; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(13899822..13900063,13900143..13900301,13900632..13901981,13902075..13903717,13903781..13903920); ID=FBpp0080138; name=Smg5-PA; parent=FBgn0019890,FBtr0080561; dbxref=FlyBase:FBpp0080138,FlyBase_Annotation_IDs:CG8954-PA,GB_protein:AAF53351.1,REFSEQ:NP_609685,GB_protein:AAF53351; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2L:complement(13899822..13900063,13900143..13900301,13900632..13901981,13902075..13903717,13903781..13903920); ID=FBpp0080139; name=Smg5-PB; parent=FBgn0019890,FBtr0080562; dbxref=FlyBase:FBpp0080139,FlyBase_Annotation_IDs:CG8954-PB,GB_protein:AAF53352.1,REFSEQ:NP_723851,GB_protein:AAF53352; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] LD36341p OS=Drosophila melanogaster GN=Smg5 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:complement(13899822..13900063,13900143..13900301,13900632..13901981,13902075..13903717,13903781..13903920); ID=FBpp0080138; name=Smg5-PA; parent=FBgn0019890,FBtr0080561; dbxref=FlyBase:FBpp0080138,FlyBase_Annotation_IDs:CG8954-PA,GB_protein:AAF53351.1,REFSEQ:NP_609685,GB_protein:AAF53351,FlyMine:FBpp0080138,modMine:FBpp0080138; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(13899822..13900063,13900143..13900301,13900632..13901981,13902075..13903717,13903781..13903920); ID=FBpp0080139; name=Smg5-PB; parent=FBgn0019890,FBtr0080562; dbxref=FlyBase:FBpp0080139,FlyBase_Annotation_IDs:CG8954-PB,GB_protein:AAF53352.1,REFSEQ:NP_723851,GB_protein:AAF53352; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0080138; name=Smg5-PA; parent=FBgn0019890,FBtr0080561; dbxref=FlyBase:FBpp0080138,FlyBase_Annotation_IDs:CG8954-PA,GB_protein:AAF53351.1,REFSEQ:NP_609685,GB_protein:AAF53351,FlyMine:FBpp0080138,modMine:FBpp0080138; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0080139; name=Smg5-PB; parent=FBgn0019890,FBtr0080562; dbxref=FlyBase:FBpp0080139,FlyBase_Annotation_IDs:CG8954-PB,GB_protein:AAF53352.1,REFSEQ:NP_723851,GB_protein:AAF53352; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0310261; name=Smg5-PC; parent=FBgn0019890,FBtr0343669; dbxref=GB_protein:AHN54428,REFSEQ:NP_001285914,FlyBase:FBpp0310261,FlyBase_Annotation_IDs:CG8954-PC; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0080138; name=Smg5-PA; parent=FBgn0019890,FBtr0080561; dbxref=FlyBase:FBpp0080138,FlyBase_Annotation_IDs:CG8954-PA,GB_protein:AAF53351.1,REFSEQ:NP_609685,GB_protein:AAF53351,FlyMine:FBpp0080138,modMine:FBpp0080138; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0080139; name=Smg5-PB; parent=FBgn0019890,FBtr0080562; dbxref=FlyBase:FBpp0080139,FlyBase_Annotation_IDs:CG8954-PB,GB_protein:AAF53352.1,REFSEQ:NP_723851,GB_protein:AAF53352; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0310261; name=Smg5-PC; parent=FBgn0019890,FBtr0343669; dbxref=GB_protein:AHN54428,REFSEQ:NP_001285914,FlyBase:FBpp0310261,FlyBase_Annotation_IDs:CG8954-PC; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] LD36341p OS=Drosophila melanogaster GN=Smg5 PE=1 SV=1 [DROME.fasta.20160308] FBpp0080138 type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0080138; name=Smg5-PA; parent=FBgn0019890,FBtr0080561; dbxref=FlyBase:FBpp0080138,FlyBase_Annotation_IDs:CG8954-PA,GB_protein:AAF53351.1,REFSEQ:NP_609685,GB_protein:AAF53351,FlyMine:FBpp0080138,modMine:FBpp0080138; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0080139 type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0080139; name=Smg5-PB; parent=FBgn0019890,FBtr0080562; dbxref=FlyBase:FBpp0080139,FlyBase_Annotation_IDs:CG8954-PB,GB_protein:AAF53352.1,REFSEQ:NP_723851,GB_protein:AAF53352; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0310261 type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0310261; name=Smg5-PC; parent=FBgn0019890,FBtr0343669; dbxref=GB_protein:AHN54428,REFSEQ:NP_001285914,FlyBase:FBpp0310261,FlyBase_Annotation_IDs:CG8954-PC; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0080138; name=Smg5-PA; parent=FBgn0019890,FBtr0080561; dbxref=FlyBase:FBpp0080138,FlyBase_Annotation_IDs:CG8954-PA,GB_protein:AAF53351.1,REFSEQ:NP_609685,GB_protein:AAF53351,UniProt/TrEMBL:Q9V414,FlyMine:FBpp0080138,modMine:FBpp0080138; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0080139; name=Smg5-PB; parent=FBgn0019890,FBtr0080562; dbxref=FlyBase:FBpp0080139,FlyBase_Annotation_IDs:CG8954-PB,GB_protein:AAF53352.1,REFSEQ:NP_723851,GB_protein:AAF53352,UniProt/TrEMBL:Q9V414; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:complement(join(13903781..13903920,13902075..13903717,13900632..13901981,13900143..13900301,13899822..13900063)); ID=FBpp0310261; name=Smg5-PC; parent=FBgn0019890,FBtr0343669; dbxref=GB_protein:AHN54428,REFSEQ:NP_001285914,FlyBase:FBpp0310261,FlyBase_Annotation_IDs:CG8954-PC,UniProt/TrEMBL:Q9V414; MD5=588652ae708cf34667bc200ea997d5c0; length=1177; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1177 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IMP] [NOT]gene silencing by miRNA [IMP] [NOT]RNA interference [IMP]
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVTFSSGGS SNASSECAID GGTNRCRGLE PNNGTCILSQ EVKDLYRSLY TASKQLDDAK  60
   61 RNVQSVGQLF QHEIEEKRSL LVQLCKQIIF KDYQSVGKKV REVMWRRGYY EFIAFVKKNW 120
  121 HKQCQDAATA QENMQKLERF LCAGIFNYKR LSARMEEIYD LDLKYLIDFS IISDGYISDM 180
  181 IGDTMESSHS GTHAVDKSLE AVSFALDTIH SSLLSLGDLH RYFLDFRIDS KLSISKEQVA 240
  241 KYYLEAFKLN PAIGMAQNQL GTLHYGQNHD LDSTYHYLYS LVCIIPFELS ENNLNKLFAK 300
  301 HTEYLERMDP EKLDFNIEDF FARFYLIVDI FFFDKEVPDF NALCHCVLID LRKILCSQQL 360
  361 RVPEPSIFKI VSILFFCLSK LKMINSPKVY SLHAFLVAAC SDLMDACIVS IEQTILARAQ 420
  421 DNERFQAEYE ERFQEFDTVV RKSRNEYKNW LAAVGECERK DKKLMPRPHS LKDCSSDSRD 480
  481 SQHSGEEAKT QEAADGDKIG EAVSTRSSDE AKESDLKTPL SCKSKRRGMR LRRRRRKIAQ 540
  541 SDDSSCYDSE SELDTDFYSD EEDYTDLSSN FDTDFSDIDA ADPGEPCGEE RYAAANYSKK 600
  601 ERKAGGGGGG GVGGVVYSDN EDVVIEEEKI VYPNEVERRS NSQEADSEEL LRSFEVLQLN 660
  661 FKSAEDAQSK PVAPPPVSFS EPPKKLVYRN KYTKINPNIV IDCLHNEPTI RALKMLFDWL 720
  721 RINPEILIGC YHSNPEFVHK IMKLLNYCNI DIFTRKVYFE RDLLTTANVR DSLVELFDVR 780
  781 ANVPLTEDFA FKNFDIFQST QITLDWETII RERVTPQEES ILRIFKMVDF GFFICKQKKF 840
  841 NYRFCVKTRR FTETQKKKQR EEKKGGGSRR RERRTAPKTN RTKRNEGRTR RYSDRKNGIV 900
  901 RKSYTSNEEK DTVEECRKMP RKGYLRNRNA EKAAAVITSA TGTSVAGGTS ASTTTNSVIE 960
  961 KLNLQSSSGA DEERSEAKSK KCELMGKLWL QNEVETLEEE LRDSPAHVVM SPFVVVDSKA1020
 1021 LTEYNGIVKS LVRTKKCIVL IPNAVLNELD DLKKRSENVR HVIRWLEQEF KQGNRHLRAQ1080
 1081 RDNESQPLSL LKISRKMDRD ASVFLQIAQF CNHLVANHAD PHVSELQKSV VTYLSGDNLH1140
 1141 EKNRQQQNFS YTGILDSIPV RYAQIQSFYA KFKANKK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Protein Overview: FBpp0310261, Smg...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: