Protein Overview: Tor-PA

General Information:
Name(s) found:	Tor-PA / FBpp0080003 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|74869525\|sp\|Q9VK45.1\|TOR_DROME RecName: Full=Target of rapamycin [NCBI NR] gi\|7297995\|gb\|AAF53237.1\| target of rapamycin [Drosophila melanogaster] [NCBI NR] gi\|17864562\|ref\|NP_524891.1\| target of rapamycin [Drosophila melanogaster] [NCBI NR] Target of rapamycin OS=Drosophila melanogaster GN=Tor PE=1 SV=1 [Swiss-Prot] The gene Target of rapamycin is referred to in FlyBase by the symbol Dmel\Tor (CG5092, FBgn0021796). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:13004786..13013201. It has the cytological map location 34A4. There is experimental evidence that it has the molecular function</span>: protein self-association. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus; determination of adult lifespan; positive regulation of cell size; regulation of cell growth; gonad development; multicellular organism growth; endocytic recycling; autophagy; positive regulation of ribosome biogenesis. 29 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; cytoplasmic part; embryonic/larval fat body; portion of tissue; vacuole; peripheral nervous system; salivary gland imaginal ring; intracellular membrane-bounded organelle; nervous system; cell cycle; multi-cell-component structure; external compound sense organ; antennal segment; adult segment. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG5092-PA translation from_gene[CG5092 Tor FBgn0021796] seq_release:3 mol_weight=281037 cds_boundaries:(2L:12,993,656..13,001,799[+]) aa_length:2470 transcript_info:[CG5092-RA seq_release:3] gene_info:[gene symbol:Tor FBgn0021796 gene_boundaries:(2L:1 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VK45) CG5092 protein [DrosMelano7227.FASTAC.txt] (AE003638) CG5092 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG5092-PA [Drosophila melanogaster]gi\|17864562\|ref\|NP_524891.1\| CG5092-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(13004786..13005011,13005067..13005287,13005431..13005997,13006353..13007086,13007146..13009087,13009136..13011691,13011766..13012932); ID=FBpp0080003; name=Tor-PA; parent=FBgn0021796,FBtr0080422; dbxref=GB_protein:AAF53237.1,FlyB [fly-100309-contam.fasta] CG5092-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Target of rapamycin CG5092-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(13004786..13005011,13005067..13005287,13005431..13005997,13006353..13007086,13007146..13009087,13009136..13011691,13011766..13012932); ID=FBpp0080003; name=Tor-PA; parent=FBgn0021796,FBtr0080422; dbxref=GB_protein:AAF53237.1,FlyBase:FBpp0080003,FlyBase_Annotation_IDs:CG5092-PA,REFSEQ:NP_524891,GB_protein:AAF53237; MD5=9fef4fd2c0caba3abf87f82def4fea2e; length=2470; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(13004786..13005011,13005067..13005287,13005431..13005997,13006353..13007086,13007146..13009087,13009136..13011691,13011766..13012932); ID=FBpp0080003; name=Tor-PA; parent=FBgn0021796,FBtr0080422; dbxref=GB_protein:AAF53237.1,FlyBase:FBpp0080003,FlyBase_Annotation_IDs:CG5092-PA,REFSEQ:NP_524891,GB_protein:AAF53237; MD5=9fef4fd2c0caba3abf87f82def4fea2e; length=2470; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2L:join(13004786..13005011,13005067..13005287,13005431..13005997,13006353..13007086,13007146..13009087,13009136..13011691,13011766..13012932); ID=FBpp0080003; name=Tor-PA; parent=FBgn0021796,FBtr0080422; dbxref=GB_protein:AAF53237.1,FlyBase:FBpp0080003,FlyBase_Annotation_IDs:CG5092-PA,REFSEQ:NP_524891,GB_protein:AAF53237,FlyMine:FBpp0080003,modMine:FBpp0080003; MD5=9fef4fd2c0caba3abf87f82def4fea2e; length=2470; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:join(13004786..13005011,13005067..13005287,13005431..13005997,13006353..13007086,13007146..13009087,13009136..13011691,13011766..13012932); ID=FBpp0080003; name=Tor-PA; parent=FBgn0021796,FBtr0080422; dbxref=GB_protein:AAF53237.1,FlyBase:FBpp0080003,FlyBase_Annotation_IDs:CG5092-PA,REFSEQ:NP_524891,GB_protein:AAF53237,FlyMine:FBpp0080003,modMine:FBpp0080003; MD5=9fef4fd2c0caba3abf87f82def4fea2e; length=2470; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(13004786..13005011,13005067..13005287,13005431..13005997,13006353..13007086,13007146..13009087,13009136..13011691,13011766..13012932); ID=FBpp0080003; name=Tor-PA; parent=FBgn0021796,FBtr0080422; dbxref=GB_protein:AAF53237.1,FlyBase:FBpp0080003,FlyBase_Annotation_IDs:CG5092-PA,REFSEQ:NP_524891,GB_protein:AAF53237,FlyMine:FBpp0080003,modMine:FBpp0080003; MD5=9fef4fd2c0caba3abf87f82def4fea2e; length=2470; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0080003 type=protein; loc=2L:join(13004786..13005011,13005067..13005287,13005431..13005997,13006353..13007086,13007146..13009087,13009136..13011691,13011766..13012932); ID=FBpp0080003; name=Tor-PA; parent=FBgn0021796,FBtr0080422; dbxref=GB_protein:AAF53237.1,FlyBase:FBpp0080003,FlyBase_Annotation_IDs:CG5092-PA,REFSEQ:NP_524891,GB_protein:AAF53237,FlyMine:FBpp0080003,modMine:FBpp0080003; MD5=9fef4fd2c0caba3abf87f82def4fea2e; length=2470; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:join(13004786..13005011,13005067..13005287,13005431..13005997,13006353..13007086,13007146..13009087,13009136..13011691,13011766..13012932); ID=FBpp0080003; name=Tor-PA; parent=FBgn0021796,FBtr0080422; dbxref=GB_protein:AAF53237.1,FlyBase:FBpp0080003,FlyBase_Annotation_IDs:CG5092-PA,REFSEQ:NP_524891,GB_protein:AAF53237,UniProt/Swiss-Prot:Q9VK45,FlyMine:FBpp0080003,modMine:FBpp0080003; MD5=9fef4fd2c0caba3abf87f82def4fea2e; length=2470; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	2470 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	multicellular organism growth [IMP] detection of nutrient [TAS] determination of adult lifespan [IMP] positive regulation of organ growth [TAS] response to nutrient [TAS] response to DNA damage stimulus [IMP] growth [TAS] positive regulation of multicellular organism growth [TAS] positive regulation of ribosome biogenesis [IMP] positive regulation of cell growth [NAS][TAS] gonad development [IMP] positive regulation of cell size [IMP][TAS] regulation of cell growth [IDA] autophagy [IMP] phosphorylation [NAS] endocytic recycling [IDA]
Molecular Function:	protein kinase activity [NAS] phosphotransferase activity, alcohol group as acceptor [IEA] protein self-association [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTSVVQQF VNGLKSRNRN VQNKATQDLL FYVKTELREM SQEELAQFFD EFDHHIFTMV  60
   61 NATDINEKKG GALAMKCLIN CEGSLTARKG ISPYLNRLRD LLLINDVSVM EIAARSLVKL 120
  121 ANMPTSKGAD SFDFDIKKAF EVLRGERQEY RRHSAVFILR ELAIALPTYF YQHILTFFEV 180
  181 IFNAIFDPKP AIRESAGEAL RAALIVTAQR ESTKQSSEPQ WYRICYDEAN GSFNADLGSS 240
  241 KDQKGVTRDD RIHGGLVVFN ELFRCANATW ERRYTSLKTL FPKTQHNKFL EASSSSSMGS 300
  301 QLNTLVPRLK VPFIDKLGST QTHLGEGEHH KGVAKFASHN VLESAYAQEI LQEHYTSICD 360
  361 NVLEQRTSKS PYVQQALLQI LPRLAAFNRA VFVEKYLQTC VSHLMQILRG KEKDRTVAYI 420
  421 TIGYMAVAVQ SAIEVHLSSI MTSVKVALPS KDLTSKRKVP VDPAVFACIT LLAHAVKSEI 480
  481 ADDVKDILEQ MFYTGLSPAL TVCLRELSEN VPQLKSAITE GLIGILSQVL MNKAAILPYT 540
  541 ALPTIAIDGS LMQNGDGATT VLALKTLGTF NFEEQNMLDF VQRCADYFIV HEQQEIRLEA 600
  601 VQTCTRLLKL AVQSSESMEN SKTLSDTVSH VIERLLMVAI TDMDCNVRIR ILRSLDETFD 660
  661 GKLAQPESLN SLFITLHDEI FEIRELAMVT IGRLSSINPA YVMPKLRTTM IELITDLKYS 720
  721 GMSRNKEQSA KMLDHLVIST PRLISSYMNP ILKALVPKLH EPESNPGVIL NVLRTIGDLA 780
  781 EVNGGSDEME LWADDLLSIL LEMLGDAGSP DKRGVALWTL GQLISATGRV VTPYHKYPVL 840
  841 IDILINFLKT EQRRSIRRET IRVLGLLGAM DPYKHKMNKG LIDSQKDNVL IAYSDGKVDE 900
  901 SQDISTAELL VNMGNALDEY YPAVAIAALM RILRDPTLST RHTSVVQAVT FIFQSLGIKC 960
  961 VPYLAQVLPN LLDNVRTADN NLREFLFQQL AILVAFVKLH IISYMGDIFK LIKEFWTINT1020
 1021 PLQNTLINLI EQIAVALGCE FRDYLAELIP QILRVLQHDN SKDRMVTRRL LQALQKFGST1080
 1081 LGYYLPLILP PIVKLFDSPY VPQQVSMVAL ETINNLACQL DFTDFSSRII HPLVRVLDAE1140
 1141 PELRDQAMTT LRSLAKQLGK KYLVFVPMVQ RTLNKHRIVD PEYEELLSKI KSCSTLADSY1200
 1201 GAGESELRPS RFKNNEPFVT DRNSNNKNLQ VTTNELRTAW QVTRRVSKDD WVEWLKRLSI1260
 1261 GLLKESPSHA LRACRSLAQE YDTLLRDLFN AAFISCWTEL SPDLKNELTQ SLIQALQVTD1320
 1321 MPEITQTILN LAEFMEHCDR DPIPIETKLL GTRAMACRAY AKALRYKEEE FLLREDSQVF1380
 1381 ESLILINNKL QQREAAEGLL TRYRNAANEL NVQGRWYEKL HNWDEALEHY ERNLKTDSSD1440
 1441 LEARLGHMRC LEALGDWSEL SNVTKHEWEN FGTEAKSRAG PLAAVAAWGL QDWEAMREYV1500
 1501 RCIPEDTQDG SYYRAVLAVH HDDFETAQRL IDETRDLLDT ELTSMAGESY ERAYGAMVCV1560
 1561 QMLAELEEVI QYKLIPERRE PLKTMWWKRL QGGQRLVEDW RRIIQVHSLV VKPHEDIHTW1620
 1621 LKYASLCRKS GSLHLSHKTL VMLLGTDPKL NPNQPLPCNQ PQVTYAYTKY MAANNQLQEA1680
 1681 YEQLTHFVST YSQELSCLPP EALKQQDQRL MARCYLRMAT WQNKLQDSIR PDAIQGALEC1740
 1741 FEKATSYDPN WYKAWHLWAY MNFKVVQAQK SALDKQQPPG ASMGMTMGSG LDSDLMIIQR1800
 1801 YAVPAVQGFF RSISLIKGNS LQDTLRLLTL WFDYGNHAEV YEALLSGMKL IEINTWLQVI1860
 1861 PQLIARIDTH RQLVGQLIHQ LLMDIGKNHP QALVYPLTVA SKSASLARRN AAFKILDSMR1920
 1921 KHSPTLVEQA VMCSEELIRV AILWHEQWHE GLEEASRLYF GDRNVKGMFE ILEPLHAMLE1980
 1981 RGPQTLKETS FSQAYGRELT EAYEWSQRYK TSAVVMDLDR AWDIYYHVFQ KISRQLPQLT2040
 2041 SLELPYVSPK LMTCKDLELA VPGSYNPGQE LIRISIIKTN LQVITSKQRP RKLCIRGSNG2100
 2101 KDYMYLLKGH EDLRQDERVM QLFSLVNTLL LDDPDTFRRN LAIQRYAVIP LSTNSGLIGW2160
 2161 VPHCDTLHTL IRDYRDKKKV PLNQEHRTML NFAPDYDHLT LMQKVEVFEH ALGQTQGDDL2220
 2221 AKLLWLKSPS SELWFERRNN YTRSLAVMSM VGYILGLGDR HPSNLMLDRM SGKILHIDFG2280
 2281 DCFEVAMTRE KFPEKIPFRL TRMLIKAMEV TGIEGTYRRT CESVMLVLRR NKDSLMAVLE2340
 2341 AFVYDPLLNW RLLDVDKKGN DAVAGAGAPG GRGGSGMQDS LSNSVEDSLP MAKSKPYDPT2400
 2401 LQQGGLHNNV ADETNSKASQ VIKRVKCKLT GTDFQTEKSV NEQSQVELLI QQATNNENLC2460
 2461 QCYIGWCPFW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.76

Protein Overview: Tor-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: