Protein Overview: FBpp0293398

General Information:
Name(s) found:	FBpp0293398 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24583884\|ref\|NP_723742.1\| bruno-2, isoform C [Drosophila melanogaster] [NCBI NR] gi\|22946324\|gb\|AAF53180.3\| bruno-2, isoform C [Drosophila melanogaster] [NCBI NR] gi\|22946323\|gb\|AAF53181.2\| bruno-2, isoform A [Drosophila melanogaster] [NCBI NR] gi\|19921186\|ref\|NP_609559.1\| bruno-2, isoform A [Drosophila melanogaster] [NCBI NR] gi\|17862264\|gb\|AAL39609.1\| LD19052p [Drosophila melanogaster] [NCBI NR] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0293398; name=bru-2-PA; parent=FBgn0262475,FBtr0304858; dbxref=REFSEQ:NP_609559,GB_protein:AAF53181,FlyBase:FBpp0293398,FlyBase:FBpp0079934,FlyBase_Annotation_IDs:CG31761-PA,FlyBase_Annotation_IDs:CG43065-PA; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0293397; name=bru-2-PC; parent=FBgn0262475,FBtr0304857; dbxref=FlyBase:FBpp0293397,FlyBase:FBpp0079933,FlyBase_Annotation_IDs:CG31761-PC,FlyBase_Annotation_IDs:CG43065-PC,FlyMine:FBpp0293397,modMine:FBpp0293397; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r5.43; species=Dmel; [FlyBase] The gene bruno-2 is referred to in FlyBase by the symbol Dmel\bru-2 (CG31761, FBgn0043904). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12344381..12397534. It has the cytological map location 33E1-33E3. Based on sequence similarity, it is predicted to have molecular function</span>: RNA binding; mRNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of translation. 4 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] >CG31761-PA translation from_gene[CG31761 bru-2 FBgn0043904] seq_release:3 mol_weight=65215 cds_boundaries:(2L:12,340,867..12,380,894[+]) aa_length:632 transcript_info:[CG31761-RA seq_release:3] gene_info:[gene symbol:bru-2 synonyms:[CG17008 CG6319] FB [hmr_yeast5_DM3-1_pombe.fasta] >CG31761-PC translation from_gene[CG31761 bru-2 FBgn0043904] seq_release:3 mol_weight=65215 cds_boundaries:(2L:12,340,867..12,380,894[+]) aa_length:632 transcript_info:[CG31761-RC seq_release:3] gene_info:[gene symbol:bru-2 synonyms:[CG17008 CG6319] FB [hmr_yeast5_DM3-1_pombe.fasta] (Q9VK98) CG31761 protein (LD19052p) [DrosMelano7227.FASTAC.txt] CG31761-PC, isoform C [Drosophila melanogaster]gi\|22946323\|gb\|AAF53181.2\| CG31761-PA, isoform A [Drosophila melanogaster]gi\|17862264\|gb\|AAL39609.1\| LD19052p [Drosophila melanogaster]gi\|24583884\|ref\|NP_723742.1\| CG31761-PC [Drosophila melanogaster]gi\|1 [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0079933; name=bru-2-PC; parent=FBgn0043904,FBtr0080351; dbxref=GB_protein:AAF53180.3,Fl [fly-100309-contam.fasta] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0079934; name=bru-2-PA; parent=FBgn0043904,FBtr0080352; dbxref=GB_protein:AAF53181.2,Fl [fly-100309-contam.fasta] bruno-2 CG31761-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta] bruno-2 CG31761-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG31761-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] LD19052p [Drosophila melanogaster] [nr-271106-contam.fasta] CG31761-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0079933; name=bru-2-PC; parent=FBgn0043904,FBtr0080351; dbxref=GB_protein:AAF53180.3,FlyBase:FBpp0079933,FlyBase_Annotation_IDs:CG31761-PC,REFSEQ:NP_723742,GB_protein:AAF53180; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0079934; name=bru-2-PA; parent=FBgn0043904,FBtr0080352; dbxref=GB_protein:AAF53181.2,FlyBase:FBpp0079934,FlyBase_Annotation_IDs:CG31761-PA,REFSEQ:NP_609559,GB_protein:AAF53181; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0079933; name=bru-2-PC; parent=FBgn0043904,FBtr0080351; dbxref=GB_protein:AAF53180.3,FlyBase:FBpp0079933,FlyBase_Annotation_IDs:CG31761-PC,REFSEQ:NP_723742,GB_protein:AAF53180; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0079934; name=bru-2-PA; parent=FBgn0043904,FBtr0080352; dbxref=GB_protein:AAF53181.2,FlyBase:FBpp0079934,FlyBase_Annotation_IDs:CG31761-PA,REFSEQ:NP_609559,GB_protein:AAF53181; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Bruno-2, isoform A OS=Drosophila melanogaster GN=bru-2 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0293398; name=bru-2-PA; parent=FBgn0262475,FBtr0304858; dbxref=REFSEQ:NP_609559,GB_protein:AAF53181,FlyBase:FBpp0293398,FlyBase:FBpp0079934,FlyBase_Annotation_IDs:CG31761-PA,FlyBase_Annotation_IDs:CG43065-PA; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] Bruno-2, isoform A OS=Drosophila melanogaster GN=bru-2 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0293398; name=bru-2-PA; parent=FBgn0262475,FBtr0304858; dbxref=REFSEQ:NP_609559,GB_protein:AAF53181,FlyBase:FBpp0293398,FlyBase:FBpp0079934,FlyBase_Annotation_IDs:CG31761-PA,FlyBase_Annotation_IDs:CG43065-PA; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0293398; name=bru-2-PA; parent=FBgn0262475,FBtr0304858; dbxref=REFSEQ:NP_609559,GB_protein:AAF53181,FlyBase:FBpp0293398,FlyBase:FBpp0079934,FlyBase_Annotation_IDs:CG31761-PA,FlyBase_Annotation_IDs:CG43065-PA; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q0E8R3, Bruno-2, isoform A OS=Drosophila melanogaster GN=bru-2 PE=2 SV=1 [DROME.fasta.20160308] FBpp0293398 type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0293398; name=bru-2-PA; parent=FBgn0262475,FBtr0304858; dbxref=REFSEQ:NP_609559,GB_protein:AAF53181,FlyBase:FBpp0293398,FlyBase:FBpp0079934,FlyBase_Annotation_IDs:CG31761-PA,FlyBase_Annotation_IDs:CG43065-PA; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:join(12351996..12352783,12358041..12358261,12359601..12359683,12362601..12362649,12385562..12385740,12389190..12389670,12391929..12392026); ID=FBpp0293398; name=bru2-PA; parent=FBgn0262475,FBtr0304858; dbxref=REFSEQ:NP_609559,GB_protein:AAF53181,FlyBase:FBpp0293398,FlyBase:FBpp0079934,FlyBase_Annotation_IDs:CG31761-PA,FlyBase_Annotation_IDs:CG43065-PA,UniProt/TrEMBL:Q7K108; MD5=ff2a3b238114874954ae37dc189f7702; length=632; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	632 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	negative regulation of translation [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] RNA binding [UNKNOWN] mRNA binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLQSLSLHA DKLSGNSPAA AAATGAAAAT SEATAVASAA AATTMLATAP VAHVANGNNS  60
   61 NSSAGSSSNS NSSSNNHSLY SNNNLNTGNN SQQQQQQQQQ HPQILPVKYE YLENLTSSGA 120
  121 TSGAIAATTT FTGAAKSFHP YLRPTGSGSN SNNSIAALST TTAATAAKMS TTLFETLLHN 180
  181 QINSSPIALP AATAIAAISA AATAATATPG TAATAAAAAA AAPSTQLNSS INSRTSLGDQ 240
  241 GGAIVVVTPA PPVAAPPTGG PNRNQSPTRD CSVKMELMES TSPDSIKDQP DADNIKMFVG 300
  301 QIPKTWDETR LRQMFEQFGP VHTLNVLRDK VTSISRGCCF VTYYTRKAAL RAQDALHNIK 360
  361 TLDGMHHPIQ MKPADSENRN ERKLFVGMLN KKYTEADVRQ LFTGHGTIEE CTVLRDQAGQ 420
  421 SKGCAFVTFA TKQNAIGAIK ALHQSQTMEG CSAPLVVKFA DTQKEKDQKK MQQIHAFCGI 480
  481 NTPSGATAGA ATPTINAATA LIAAPPSAGR TNPSMAAALA AVPQVQQAGS AATAPTTLVP 540
  541 LNSTTALSAS LTPNLLATNA AHQGAAAAAA YLGADPAAAA HLQLYQQLHG YGLSPAHYLP 600
  601 DESKKSTKEK KKTSSSTVFP AFLCPFSDLQ FL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: FBpp0293398

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: