Protein Overview: prd-PB

General Information:
Name(s) found:	prd-PB / FBpp0079882 [FlyBase]
Description(s) found: SHOW ONLY BEST	pir\|\|A26062 paired box segmentation protein prd - fruit fly (Drosophila melanogaster) [NCBI NR] gi\|24583824\|ref\|NP_723721.1\| paired, isoform B [Drosophila melanogaster] [NCBI NR] gi\|22946299\|gb\|AAN10801.1\| paired, isoform B [Drosophila melanogaster] [NCBI NR] gi\|158160\|gb\|AAB59221.1\| segmentation protein [Drosophila melanogaster] [NCBI NR] gi\|123412\|sp\|P06601.1\|PRD_DROME RecName: Full=Segmentation protein paired [NCBI NR] Segmentation protein paired OS=Drosophila melanogaster GN=prd PE=1 SV=1 [Swiss-Prot] (P06601) Segmentation protein paired [Swiss-Prot] The gene paired is referred to in FlyBase by the symbol Dmel\prd (CG6716, FBgn0003145). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12082997..12085792. It has the cytological map location 33C3. There is experimental evidence that it has the molecular function</span>: sequence-specific DNA binding; transcription activator activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of transcription, DNA-dependent. 72 alleles are reported. The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; cuticle; abdominal ventral denticle belt; embryonic neuron; embryonic nervous system; larval abdominal segment; thoracic segment; metathoracic ventral denticle belt; male accessory gland; adult; embryonic heart; gastrula embryo; embryonic segment; external compound sense organ; syncytial blastoderm embryo; antennal segment. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG6716-PB translation from_gene[CG6716 prd FBgn0003145] seq_release:3 mol_weight=65498 cds_boundaries:(2L:12,072,188..12,074,400[-]) aa_length:613 transcript_info:[CG6716-RB seq_release:3] gene_info:[gene symbol:prd FBgn0003145 gene_boundaries:(2L:12, [hmr_yeast5_DM3-1_pombe.fasta] CG6716-PB, isoform B [Drosophila melanogaster]gi\|24583824\|ref\|NP_723721.1\| CG6716-PB [Drosophila melanogaster]gi\|85138\|pir\|\|A26062 paired box segmentation protein prd - fruit fly (Drosophila melanogaster)gi\|158160\|gb\|AAB59221.1\| segmentation protein [D [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:complement(12083314..12085088,12085463..12085529); ID=FBpp0079882; name=prd-PB; parent=FBgn0003145,FBtr0080298; dbxref=FlyBase_Annotation_IDs:CG6716-PB,FlyBase:FBpp0079882,GB_protein:AAN10801.1,REFSEQ:NP_723721,GB_protein:AAN10801; MD [fly-100309-contam.fasta] paired CG6716-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] segmentation protein [Drosophila melanogaster] [nr-271106-contam.fasta] CG6716-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] Segmentation protein paired [nr-271106-contam.fasta] type=protein; loc=2L:complement(12083314..12085088,12085463..12085529); ID=FBpp0079882; name=prd-PB; parent=FBgn0003145,FBtr0080298; dbxref=FlyBase_Annotation_IDs:CG6716-PB,FlyBase:FBpp0079882,GB_protein:AAN10801.1,REFSEQ:NP_723721,GB_protein:AAN10801; MD5=770d55839eaa7930dd53fa572847522c; length=613; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(12083314..12085088,12085463..12085529); ID=FBpp0079882; name=prd-PB; parent=FBgn0003145,FBtr0080298; dbxref=FlyBase_Annotation_IDs:CG6716-PB,FlyBase:FBpp0079882,GB_protein:AAN10801.1,REFSEQ:NP_723721,GB_protein:AAN10801; MD5=770d55839eaa7930dd53fa572847522c; length=613; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2L:complement(12083314..12085088,12085463..12085529); ID=FBpp0079882; name=prd-PB; parent=FBgn0003145,FBtr0080298; dbxref=FlyBase_Annotation_IDs:CG6716-PB,FlyBase:FBpp0079882,GB_protein:AAN10801.1,REFSEQ:NP_723721,GB_protein:AAN10801,FlyMine:FBpp0079882,modMine:FBpp0079882; MD5=770d55839eaa7930dd53fa572847522c; length=613; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(join(12085463..12085529,12083314..12085088)); ID=FBpp0079882; name=prd-PB; parent=FBgn0003145,FBtr0080298; dbxref=FlyBase_Annotation_IDs:CG6716-PB,FlyBase:FBpp0079882,GB_protein:AAN10801.1,REFSEQ:NP_723721,GB_protein:AAN10801,FlyMine:FBpp0079882,modMine:FBpp0079882; MD5=770d55839eaa7930dd53fa572847522c; length=613; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(12085463..12085529,12083314..12085088)); ID=FBpp0079882; name=prd-PB; parent=FBgn0003145,FBtr0080298; dbxref=FlyBase_Annotation_IDs:CG6716-PB,FlyBase:FBpp0079882,GB_protein:AAN10801.1,REFSEQ:NP_723721,GB_protein:AAN10801,FlyMine:FBpp0079882,modMine:FBpp0079882; MD5=770d55839eaa7930dd53fa572847522c; length=613; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0079882 type=protein; loc=2L:complement(join(12085463..12085529,12083314..12085088)); ID=FBpp0079882; name=prd-PB; parent=FBgn0003145,FBtr0080298; dbxref=FlyBase_Annotation_IDs:CG6716-PB,FlyBase:FBpp0079882,GB_protein:AAN10801.1,REFSEQ:NP_723721,GB_protein:AAN10801,FlyMine:FBpp0079882,modMine:FBpp0079882; MD5=770d55839eaa7930dd53fa572847522c; length=613; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(12085463..12085529,12083314..12085088)); ID=FBpp0079882; name=prd-PB; parent=FBgn0003145,FBtr0080298; dbxref=FlyBase_Annotation_IDs:CG6716-PB,FlyBase:FBpp0079882,GB_protein:AAN10801.1,REFSEQ:NP_723721,GB_protein:AAN10801,UniProt/Swiss-Prot:P06601,FlyMine:FBpp0079882,modMine:FBpp0079882; MD5=770d55839eaa7930dd53fa572847522c; length=613; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	613 amino acids
Gene Ontology:
Cellular Component:	transcription factor complex [ISS] nucleus [NAS]
Biological Process:	positive regulation of transcription, DNA-dependent [IDA] periodic partitioning by pair rule gene [NAS][TAS] regulation of transcription, DNA-dependent [IEA] regulation of transcription [IEA][ISS]
Molecular Function:	DNA binding [NAS] transcription factor activity [ISS] sequence-specific DNA binding [IDA] transcription activator activity [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTAFAAAM HRPFFNGYST MQDMNSGQGR VNQLGGVFIN GRPLPNNIRL KIVEMAADGI  60
   61 RPCVISRQLR VSHGCVSKIL NRYQETGSIR PGVIGGSKPR IATPEIENRI EEYKRSSPGM 120
  121 FSWEIREKLI REGVCDRSTA PSVSAISRLV RGRDAPLDND MSSASGSPAG DGTKASSSCG 180
  181 SDVSGGHHNN GKPSDEDISD CESEPGIALK RKQRRCRTTF SASQLDELER AFERTQYPDI 240
  241 YTREELAQRT NLTEARIQVW FSNRRARLRK QHTSVSGGAP GGAAASVSHV AASSSLPSVV 300
  301 SSVPSMAPLA MMPGSLDPAT VYQQQYDFYG SHANISVSAA APMASSNLSP GITTTPPHHH 360
  361 QFYNPSANTA SYIMPGENGN TTPTGNIIVS SYETQLGSVY GTETETHQTM PRNESPNESV 420
  421 SSAFGQLPPT PNSLSAVVSG AGVTSSSGAN SGADPSQSLA NASAGSEELS AALKVESVDL 480
  481 IAASQSQLYG GWSSMQALRP NAPLSPEDSL NSTSSTSQAL DVTAHQMFHP YQHTPQYASY 540
  541 PAPGHAHSHH GHPHAPHPHA HPHPQYAGAH PHYPPPSSSA HFMPQNFNAA AFPSPSKVNY 600
  601 TTMPPQPFYP SWY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.74

Protein Overview: prd-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: