Protein Overview: Tom70-PB, Tom70-...

General Information:
Name(s) found:	Tom70-PC / FBpp0079895 [FlyBase] Tom70-PB / FBpp0079894 [FlyBase] Tom70-PA / FBpp0079893 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|253314551\|gb\|ACT22579.1\| FI03495p [Drosophila melanogaster] [NCBI NR] gi\|24583797\|ref\|NP_723712.1\| translocase of outer membrane 70, isoform C [Drosophila melanogaster] [NCBI NR] gi\|24583795\|ref\|NP_723711.1\| translocase of outer membrane 70, isoform B [Drosophila melanogaster] [NCBI NR] gi\|24583793\|ref\|NP_609536.1\| translocase of outer membrane 70, isoform A [Drosophila melanogaster] [NCBI NR] gi\|22946292\|gb\|AAN10798.1\| translocase of outer membrane 70, isoform C [Drosophila melanogaster] [NCBI NR] gi\|22946291\|gb\|AAN10797.1\| translocase of outer membrane 70, isoform B [Drosophila melanogaster] [NCBI NR] gi\|22946290\|gb\|AAF53148.2\| translocase of outer membrane 70, isoform A [Drosophila melanogaster] [NCBI NR] The gene Translocase of outer membrane 70 is referred to in FlyBase by the symbol Dmel\Tom70 (CG6756, FBgn0032397). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12035995..12038543. It has the cytological map location 33B9-33B10. Based on sequence similarity, it is predicted to have molecular function</span>: P-P-bond-hydrolysis-driven protein transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protein targeting to mitochondrion. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] >CG6756-PC translation from_gene[CG6756 CG6756 FBgn0032397] seq_release:3 mol_weight=66365 cds_boundaries:(2L:12,025,145..12,027,001[-]) aa_length:589 transcript_info:[CG6756-RC seq_release:3] gene_info:[gene symbol:CG6756 FBgn0032397 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta] >CG6756-PB translation from_gene[CG6756 CG6756 FBgn0032397] seq_release:3 mol_weight=66365 cds_boundaries:(2L:12,025,145..12,027,001[-]) aa_length:589 transcript_info:[CG6756-RB seq_release:3] gene_info:[gene symbol:CG6756 FBgn0032397 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta] >CG6756-PA translation from_gene[CG6756 CG6756 FBgn0032397] seq_release:3 mol_weight=66365 cds_boundaries:(2L:12,025,145..12,027,001[-]) aa_length:589 transcript_info:[CG6756-RA seq_release:3] gene_info:[gene symbol:CG6756 FBgn0032397 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta] (Q9VKC8) CG6756 protein [DrosMelano7227.FASTAC.txt] CG6756-PC, isoform C [Drosophila melanogaster]gi\|22946291\|gb\|AAN10797.1\| CG6756-PB, isoform B [Drosophila melanogaster]gi\|22946290\|gb\|AAF53148.2\| CG6756-PA, isoform A [Drosophila melanogaster]gi\|24583797\|ref\|NP_723712.1\| CG6756-PC [Drosophila melanogas [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079893; name=Tom70-PA; parent=FBgn0032397,FBtr0080309; dbxref=FlyBase:FBpp0079893,FlyBase_Annotation_IDs:CG6756-PA,GB_protein:AAF53148.2,REFSEQ:NP_609536,GB_protein:AAF53148; [fly-100309-contam.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079894; name=Tom70-PB; parent=FBgn0032397,FBtr0080310; dbxref=FlyBase:FBpp0079894,FlyBase_Annotation_IDs:CG6756-PB,GB_protein:AAN10797.1,REFSEQ:NP_723711,GB_protein:AAN10797; [fly-100309-contam.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079895; name=Tom70-PC; parent=FBgn0032397,FBtr0080311; dbxref=FlyBase:FBpp0079895,FlyBase_Annotation_IDs:CG6756-PC,GB_protein:AAN10798.1,REFSEQ:NP_723712,GB_protein:AAN10798; [fly-100309-contam.fasta] CG6756-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta] CG6756-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] Translocase of outer membrane 70 CG6756-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta] CG6756-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Translocase of outer membrane 70 CG6756-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Translocase of outer membrane 70 CG6756-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079893; name=Tom70-PA; parent=FBgn0032397,FBtr0080309; dbxref=FlyBase:FBpp0079893,FlyBase_Annotation_IDs:CG6756-PA,GB_protein:AAF53148.2,REFSEQ:NP_609536,GB_protein:AAF53148; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079894; name=Tom70-PB; parent=FBgn0032397,FBtr0080310; dbxref=FlyBase:FBpp0079894,FlyBase_Annotation_IDs:CG6756-PB,GB_protein:AAN10797.1,REFSEQ:NP_723711,GB_protein:AAN10797; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079895; name=Tom70-PC; parent=FBgn0032397,FBtr0080311; dbxref=FlyBase:FBpp0079895,FlyBase_Annotation_IDs:CG6756-PC,GB_protein:AAN10798.1,REFSEQ:NP_723712,GB_protein:AAN10798; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079893; name=Tom70-PA; parent=FBgn0032397,FBtr0080309; dbxref=FlyBase:FBpp0079893,FlyBase_Annotation_IDs:CG6756-PA,GB_protein:AAF53148.2,REFSEQ:NP_609536,GB_protein:AAF53148; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079894; name=Tom70-PB; parent=FBgn0032397,FBtr0080310; dbxref=FlyBase:FBpp0079894,FlyBase_Annotation_IDs:CG6756-PB,GB_protein:AAN10797.1,REFSEQ:NP_723711,GB_protein:AAN10797; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079895; name=Tom70-PC; parent=FBgn0032397,FBtr0080311; dbxref=FlyBase:FBpp0079895,FlyBase_Annotation_IDs:CG6756-PC,GB_protein:AAN10798.1,REFSEQ:NP_723712,GB_protein:AAN10798; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] FI03495p OS=Drosophila melanogaster GN=Tom70 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079893; name=Tom70-PA; parent=FBgn0032397,FBtr0080309; dbxref=FlyBase:FBpp0079893,FlyBase_Annotation_IDs:CG6756-PA,GB_protein:AAF53148.2,REFSEQ:NP_609536,GB_protein:AAF53148,FlyMine:FBpp0079893,modMine:FBpp0079893; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079894; name=Tom70-PB; parent=FBgn0032397,FBtr0080310; dbxref=FlyBase:FBpp0079894,FlyBase_Annotation_IDs:CG6756-PB,GB_protein:AAN10797.1,REFSEQ:NP_723711,GB_protein:AAN10797; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(12036271..12037064,12037155..12038130); ID=FBpp0079895; name=Tom70-PC; parent=FBgn0032397,FBtr0080311; dbxref=FlyBase:FBpp0079895,FlyBase_Annotation_IDs:CG6756-PC,GB_protein:AAN10798.1,REFSEQ:NP_723712,GB_protein:AAN10798; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] FI03495p OS=Drosophila melanogaster GN=Tom70 PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079893; name=Tom70-PA; parent=FBgn0032397,FBtr0080309; dbxref=FlyBase:FBpp0079893,FlyBase_Annotation_IDs:CG6756-PA,GB_protein:AAF53148.2,REFSEQ:NP_609536,GB_protein:AAF53148,FlyMine:FBpp0079893,modMine:FBpp0079893; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079894; name=Tom70-PB; parent=FBgn0032397,FBtr0080310; dbxref=FlyBase:FBpp0079894,FlyBase_Annotation_IDs:CG6756-PB,GB_protein:AAN10797.1,REFSEQ:NP_723711,GB_protein:AAN10797; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079895; name=Tom70-PC; parent=FBgn0032397,FBtr0080311; dbxref=FlyBase:FBpp0079895,FlyBase_Annotation_IDs:CG6756-PC,GB_protein:AAN10798.1,REFSEQ:NP_723712,GB_protein:AAN10798; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079895; name=Tom70-PC; parent=FBgn0032397,FBtr0080311; dbxref=FlyBase:FBpp0079895,FlyBase_Annotation_IDs:CG6756-PC,GB_protein:AAN10798.1,REFSEQ:NP_723712,GB_protein:AAN10798; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079893; name=Tom70-PA; parent=FBgn0032397,FBtr0080309; dbxref=FlyBase:FBpp0079893,FlyBase_Annotation_IDs:CG6756-PA,GB_protein:AAF53148.2,REFSEQ:NP_609536,GB_protein:AAF53148,FlyMine:FBpp0079893,modMine:FBpp0079893; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079894; name=Tom70-PB; parent=FBgn0032397,FBtr0080310; dbxref=FlyBase:FBpp0079894,FlyBase_Annotation_IDs:CG6756-PB,GB_protein:AAN10797.1,REFSEQ:NP_723711,GB_protein:AAN10797; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0079893 type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079893; name=Tom70-PA; parent=FBgn0032397,FBtr0080309; dbxref=FlyBase:FBpp0079893,FlyBase_Annotation_IDs:CG6756-PA,GB_protein:AAF53148.2,REFSEQ:NP_609536,GB_protein:AAF53148,FlyMine:FBpp0079893,modMine:FBpp0079893; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0079894 type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079894; name=Tom70-PB; parent=FBgn0032397,FBtr0080310; dbxref=FlyBase:FBpp0079894,FlyBase_Annotation_IDs:CG6756-PB,GB_protein:AAN10797.1,REFSEQ:NP_723711,GB_protein:AAN10797; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0079895 type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079895; name=Tom70-PC; parent=FBgn0032397,FBtr0080311; dbxref=FlyBase:FBpp0079895,FlyBase_Annotation_IDs:CG6756-PC,GB_protein:AAN10798.1,REFSEQ:NP_723712,GB_protein:AAN10798; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079893; name=Tom70-PA; parent=FBgn0032397,FBtr0080309; dbxref=FlyBase:FBpp0079893,FlyBase_Annotation_IDs:CG6756-PA,GB_protein:AAF53148.2,REFSEQ:NP_609536,GB_protein:AAF53148,UniProt/TrEMBL:Q9VKC8,FlyMine:FBpp0079893,modMine:FBpp0079893; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079894; name=Tom70-PB; parent=FBgn0032397,FBtr0080310; dbxref=FlyBase:FBpp0079894,FlyBase_Annotation_IDs:CG6756-PB,GB_protein:AAN10797.1,REFSEQ:NP_723711,GB_protein:AAN10797,UniProt/TrEMBL:Q9VKC8; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:complement(join(12037155..12038130,12036271..12037064)); ID=FBpp0079895; name=Tom70-PC; parent=FBgn0032397,FBtr0080311; dbxref=FlyBase:FBpp0079895,FlyBase_Annotation_IDs:CG6756-PC,GB_protein:AAN10798.1,REFSEQ:NP_723712,GB_protein:AAN10798,UniProt/TrEMBL:Q9VKC8; MD5=e8b1482c65ac2a5ee7a6c2be549f0d73; length=589; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	589 amino acids
Gene Ontology:
Cellular Component:	mitochondrial outer membrane translocase complex [ISS]
Biological Process:	protein targeting to mitochondrion [ISS]
Molecular Function:	P-P-bond-hydrolysis-driven protein transmembrane transporter activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMTLNIGSM KLTKWQLALI LGTPLAIGLG TYAVKSWTAA SKELDGEKKR PKAKIEKQAI  60
   61 SLDGTAPDQE LERNQKSAEL GEKLSPLKEA NNYKTEGNNC YRNGKYDEAI KFYDKAIDKC 120
  121 PKEHRTDMAI FYQNRAASYE MLKKWSNVKE DCTASLEFNP RYAKAYYRRA RAHEATKDMN 180
  181 ECLDDVTATC ILEMFQNNQT IMFADRVLKE TGRLDAEKGM RNRVPVVPSA CFVNTYTRSF 240
  241 IADPLQTMKV PAPKSDAPPK GFLRAHLAFL EEKYEEIIPA CTEEIESSEA EAQYKVEALL 300
  301 MRGTFHLLCG SYVESQQDFD AIIANDYADP NLRAYAYIKR AALYIQLDQR EKGIADFAEA 360
  361 ERLNPENPDV YHQRAQILLL LEQIEPALAE FEKAVSIAPN HAIAFVQKCY AEYRLSLLAG 420
  421 DQRRLESVMH TFQNAIERFP SCVECYSLTA QVLADQQQFT QAEEYYKKAM VLAPTNPALI 480
  481 VHQAIMVLQW RGDINLAVQL LNKAIEVDPK CELAYETLGT VEVQRAQLTR AVELFEKALL 540
  541 YAKSQAELVH VYSLRNAAVA QINVTKKLGI DMNSVSAMAQ SGLMAQGVA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Tom70-PB, Tom70-...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: