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Protein Overview: dUTPase-PA

General Information:
Name(s) found: dUTPase-PA / FBpp0079746 [FlyBase]
Description(s) found:
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  • gi|7297803|gb|AAF53053.1| deoxyuridine triphosphatase, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|5679098|gb|AAD46856.1|AF160916_1 BcDNA.LD08534 [Drosophila melanogaster] [NCBI NR]
  • pir||JC7565 nucleoside-triphosphatase (EC 3.6.1.15) - fruit fly (Drosophila melanogaster) [NCBI NR]
  • gi|19921126|ref|NP_609479.1| deoxyuridine triphosphatase, isoform A [Drosophila melanogaster] [NCBI NR]
  • The gene Deoxyuridine triphosphatase is referred to in FlyBase by the symbol Dmel\dUTPase (CG4584, FBgn0250837). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11011332..11012138. It has the cytological map location 32C1. There is experimental evidence that it has the molecular function</span>: dUTP diphosphatase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: dUTP metabolic process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG4584-PA translation from_gene[CG4584 BcDNA:LD08534 FBgn0027890] seq_release:3 mol_weight=19959 cds_boundaries:(2L:11,003,850..11,004,413[+]) aa_length:188 transcript_info:[CG4584-RA seq_release:3] gene_info:[gene symbol:BcDNA:LD08534 FBgn0027890 gen [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V3I1) BCDNA:LD08534 protein [DrosMelano7227.FASTAC.txt]
  • (AE003630) BcDNA:LD08534 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG4584-PA, isoform A [Drosophila melanogaster]gi|5679098|gb|AAD46856.1| BcDNA.LD08534 [Drosophila melanogaster]gi|19921126|ref|NP_609479.1| CG4584-PA [Drosophila melanogaster]gi|25392170|pir||JC7565 nucleoside-triphosphatase (EC 3.6.1.15) - fruit fly [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:11011441..11012007; ID=FBpp0079746; name=dUTPase-PA; parent=FBgn0250837,FBtr0080157; dbxref=FlyBase:FBpp0079746,FlyBase_Annotation_IDs:CG4584-PA,GB_protein:AAF53053.1,REFSEQ:NP_609479,GB_protein:AAF53053; MD5=c0b93970078e4e793b7679439 [fly-100309-contam.fasta]
  • BcDNA.LD08534 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Deoxyuridine triphosphatase CG4584-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG4584-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:11011441..11012007; ID=FBpp0079746; name=dUTPase-PA; parent=FBgn0250837,FBtr0080157; dbxref=FlyBase:FBpp0079746,FlyBase_Annotation_IDs:CG4584-PA,GB_protein:AAF53053.1,REFSEQ:NP_609479,GB_protein:AAF53053; MD5=c0b93970078e4e793b7679439bed9aa2; length=188; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:11011441..11012007; ID=FBpp0079746; name=dUTPase-PA; parent=FBgn0250837,FBtr0080157; dbxref=FlyBase:FBpp0079746,FlyBase_Annotation_IDs:CG4584-PA,GB_protein:AAF53053.1,REFSEQ:NP_609479,GB_protein:AAF53053; MD5=c0b93970078e4e793b7679439bed9aa2; length=188; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • BcDNA.LD08534 OS=Drosophila melanogaster GN=dUTPase PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:11011441..11012007; ID=FBpp0079746; name=dUTPase-PA; parent=FBgn0250837,FBtr0080157; dbxref=FlyBase:FBpp0079746,FlyBase_Annotation_IDs:CG4584-PA,GB_protein:AAF53053.1,REFSEQ:NP_609479,GB_protein:AAF53053,FlyMine:FBpp0079746,modMine:FBpp0079746; MD5=c0b93970078e4e793b7679439bed9aa2; length=188; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:11011441..11012007; ID=FBpp0079746; name=dUTPase-PA; parent=FBgn0250837,FBtr0080157; dbxref=FlyBase:FBpp0079746,FlyBase_Annotation_IDs:CG4584-PA,GB_protein:AAF53053.1,REFSEQ:NP_609479,GB_protein:AAF53053,FlyMine:FBpp0079746,modMine:FBpp0079746; MD5=c0b93970078e4e793b7679439bed9aa2; length=188; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:11011441..11012007; ID=FBpp0079746; name=dUTPase-PA; parent=FBgn0250837,FBtr0080157; dbxref=FlyBase:FBpp0079746,FlyBase_Annotation_IDs:CG4584-PA,GB_protein:AAF53053.1,REFSEQ:NP_609479,GB_protein:AAF53053,FlyMine:FBpp0079746,modMine:FBpp0079746; MD5=c0b93970078e4e793b7679439bed9aa2; length=188; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0079746 type=protein; loc=2L:11011441..11012007; ID=FBpp0079746; name=dUTPase-PA; parent=FBgn0250837,FBtr0080157; dbxref=FlyBase:FBpp0079746,FlyBase_Annotation_IDs:CG4584-PA,GB_protein:AAF53053.1,REFSEQ:NP_609479,GB_protein:AAF53053,FlyMine:FBpp0079746,modMine:FBpp0079746; MD5=c0b93970078e4e793b7679439bed9aa2; length=188; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:11011441..11012007; ID=FBpp0079746; name=dUTPase-PA; parent=FBgn0250837,FBtr0080157; dbxref=FlyBase:FBpp0079746,FlyBase_Annotation_IDs:CG4584-PA,GB_protein:AAF53053.1,REFSEQ:NP_609479,GB_protein:AAF53053,UniProt/TrEMBL:Q9V3I1,FlyMine:FBpp0079746,modMine:FBpp0079746; MD5=c0b93970078e4e793b7679439bed9aa2; length=188; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 188 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: dUTP metabolic process [IEA]
    Molecular Function: dUTP diphosphatase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSTDFADIP AAKKMKIDTC VLRFAKLTEN ALEPVRGSAK AAGVDLRSAY DVVVPARGKA  60
   61 IVKTDLQVQV PEGSYGRVAP RSGLAVKNFI DVGAGVVDED YRGNLGVVLF NHSDVDFEVK 120
  121 HGDRIAQFIC ERIFYPQLVM VDKLEDTERG EAGFGSTGVK DLPAAKAQNG NGEKAAEPEG 180
  181 AAPAPVAT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..188] PSI-BLAST 45.69897 No description for 2hquA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleoside-triphosphate diphosphatase activity
    		•  5.64898078077484 bayes_pls_golite062009
  • dUTP diphosphatase activity
    		•  5.62861923551608 bayes_pls_golite062009
  • hydrolase activity
    		•  1.8120510491809 bayes_pls_golite062009
  • catalytic activity
    		•  1.71668532866244 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.43042083356989 bayes_pls_golite062009
  • binding
    		•  1.21193927389015 bayes_pls_golite062009
  • peroxisome proliferator activated receptor binding
    		•  1.01014631701573 bayes_pls_golite062009
  • pyrimidine deoxyribonucleotide binding
    		•  0.378438138772693 bayes_pls_golite062009
  • pyrimidine nucleotide binding
    		•  0.26077271033521 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle