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View Structure Prediction Details

Protein: dUTPase-PA
Organism: Drosophila melanogaster
Length: 188 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dUTPase-PA.

Description E-value Query
Range
Subject
Range
gi|38047903 - gi|38047903|gb|AAR09854.1| similar to Drosophila melanogaster BcDNA:LD08534 [Drosophila yakuba]
193.0 [0..1] [173..1]
gi|38503762 - gi|38503762|gb|AAR22676.1| pol protein [Small ruminant lentivirus]
191.0 [0..13] [176..1]
gi|418710 - pir||B45345 HIV-1 retropepsin (EC 3.4.23.16) - caprine arthritis-encephalitis virus (strain CO)
POL_CAEVC - Pol polyprotein OS=Caprine arthritis encephalitis virus (strain Cork) GN=pol PE=3 SV=1
191.0 [0..8] [176..675]
gi|9626653, gi|3... - gi|9626653|ref|NP_040939.1| pol protein [Caprine arthritis-encephalitis virus], gi|323296|gb|AAA9182...
191.0 [0..8] [176..671]

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Predicted Domain #1
Region A:
Residues: [1-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSTDFADIP AAKKMKIDTC VLRFAKLTEN ALEPVRGSAK AAGVDLRSAY DVVVPARGKA  60
   61 IVKTDLQVQV PEGSYGRVAP RSGLAVKNFI DVGAGVVDED YRGNLGVVLF NHSDVDFEVK 120
  121 HGDRIAQFIC ERIFYPQLVM VDKLEDTERG EAGFGSTGVK DLPAAKAQNG NGEKAAEPEG 180
  181 AAPAPVAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.69897
Match: 2hquA
Description: No description for 2hquA was found.

Predicted functions:

Term Confidence Notes
nucleoside-triphosphate diphosphatase activity 5.64898078077484 bayes_pls_golite062009
dUTP diphosphatase activity 5.62861923551608 bayes_pls_golite062009
hydrolase activity 1.8120510491809 bayes_pls_golite062009
catalytic activity 1.71668532866244 bayes_pls_golite062009
pyrophosphatase activity 1.43042083356989 bayes_pls_golite062009
binding 1.21193927389015 bayes_pls_golite062009
peroxisome proliferator activated receptor binding 1.01014631701573 bayes_pls_golite062009
pyrimidine deoxyribonucleotide binding 0.378438138772693 bayes_pls_golite062009
pyrimidine nucleotide binding 0.26077271033521 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle